Plasmodium vivax and the importance of the subtelomeric multigene vir superfamily

Trends in Parasitology

Volumn 25, Issue 1, 2009, Pages 44-51

  Fernandez Becerra, Carmen ^a   Yamamoto, Marcio M ^b   Vêncio, Ricardo Z N ^b,c   Lacerda, Marcus ^d   Rosanas Urgell, Anna ^a   del Portillo, Hernando A ^a,e  

^a HOSPITAL CLÍNIC   (Spain)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^d FUNDAÇÃO DE MEDICINA TROPICAL DR HEITOR VIEIRA DOURADO   (Brazil)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE;

AMINO ACID SEQUENCE; CELLULAR DISTRIBUTION; GENE EXPRESSION; GENE SEQUENCE; HUMAN; MALARIA FALCIPARUM; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMODIUM VIVAX; PLASMODIUM VIVAX MALARIA; PREVALENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTOZOAL GENETICS; REVIEW; SPLEEN; SYMPTOM; VIR GENE;

ANIMALS; GENES, PROTOZOAN; HUMANS; MALARIA, VIVAX; MULTIGENE FAMILY; PLASMODIUM VIVAX;

PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; VIR;

EID: 58149204121     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2008.09.012     Document Type: Review

References (75)

1. Mendis K., et al. The neglected burden of Plasmodium vivax malaria. Am. J. Trop. Med. Hyg. 64 (2001) 97-106
2. Guerra C.A., et al. Mapping the global extent of malaria in 2005. Trends Parasitol. 22 (2006) 353-358
3. Price R.N., et al. Vivax malaria: neglected and not benign. Am. J. Trop. Med. Hyg. 77 (2007) 79-87
4. Baird J.K. Chloroquine resistance in Plasmodium vivax. Antimicrob. Agents Chemother. 48 (2004) 4075-4083
5. Kochar D.K., et al. Plasmodium vivax malaria. Emerg. Infect. Dis. 11 (2005) 132-134
6. Snounou G., and White N.J. The co-existence of Plasmodium: sidelights from falciparum and vivax malaria in Thailand. Trends Parasitol. 20 (2004) 333-339
7. Collins W.E., and Jeffery G.M. A retrospective examination of secondary sporozoite-and trophozoite-induced infections with Plasmodium falciparum: development of parasitologic and clinical immunity following secondary infection. Am. J. Trop. Med. Hyg. 61 (1999) 20-35
8. Herrera S., et al. An update on the search for a Plasmodium vivax vaccine. Trends Parasitol. 23 (2007) 122-128
9. Vekemans J., and Ballou W.R. Plasmodium falciparum malaria vaccines in development. Expert Rev. Vaccines 7 (2008) 223-240
10. Miller L.H., et al. The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy. N. Engl. J. Med. 5 (1976) 302-304
11. Ryan J.R., et al. Evidence for transmission of Plasmodium vivax among a duffy antigen negative population in Western Kenya. Am. J. Trop. Med. Hyg. 75 (2006) 575-581
12. Cavasini C.E., et al. Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?. Trans. R. Soc. Trop. Med. Hyg. 101 (2007) 1042-1044
13. Fang X.D., et al. Cloning of the Plasmodium vivax Duffy receptor. Mol. Biochem. Parasitol. 44 (1991) 125-132
14. Chitnis C.E., et al. Identification of the erythrocyte binding domains of Plasmodium vivax and Plasmodium knowlesi proteins involved in erythrocyte invasion. J. Exp. Med. 1 (1994) 497-506
15. Singh S., et al. Biochemical, biophysical, and functional characterization of bacterially expressed and refolded receptor binding domain of Plasmodium vivax duffy-binding protein. J. Biol. Chem. 276 (2001) 17111-17116
16. Arévalo-Herrera M., et al. Immunogenicity and protective efficacy of recombinant vaccine based on the receptor-binding domain of the Plasmodium vivax Duffy binding protein in Aotus monkeys. Am. J. Trop. Med. Hyg. 73 (2005) 25-31
17. Singh S.K., et al. Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain. Nature 439 (2005) 741-744
18. del Portillo H.A., et al. A superfamily of variant genes encoded in the subtelomeric region of Plasmodium vivax. Nature 12 (2001) 839-842
19. Fernandez-Becerra C., et al. Variant proteins of Plasmodium vivax are not clonally expressed in natural infections. Mol. Microbiol. 58 (2005) 648-658
20. Oliveira T.R., et al. Evaluation of the acquired immune responses to Plasmodium vivax VIR variant antigens in individuals living in malaria-endemic areas of Brazil. Malar. J. 6 (2006) 83-93
21. del Portillo H.A., et al. Variant genes and the spleen in Plasmodium vivax malaria. Int. J. Parasitol. 34 (2004) 1547-1554
22. Carlton J., et al. Comparative genomics of the neglected human parasite Plasmodium vivax. Nature 455 (2008) 757-763
23. Janssen C.S., et al. A large gene family for putative variant antigens shared by human and rodent malaria parasites. Proc. Biol. Sci 269 (2002) 431-436
24. Janssen C.S., et al. Plasmodium interspersed repeats: the major multigene superfamily of malaria parasites. Nucleic Acids Res. 26 (2004) 5712-5720
25. Merino E.F., et al. Multi-character population study of the vir subtelomeric multigene superfamily of Plasmodium vivax, a major human malaria parasite. Mol. Biochem. Parasitol. 149 (2006) 10-16
26. Fonager J., et al. Transcription and alternative splicing in the yir multigene family of the malaria parasite Plasmodium y. yoelii: identification of motifs suggesting epigenetic and post-transcriptional control of RNA expression. Mol. Biochem. Parasitol. 156 (2007) 1-11
27. Cunningham D.A., et al. Host immunity modulates transcriptional changes in a multigene family (yir) of rodent malaria. Mol. Microbiol. 58 (2005) 636-647
28. Pain, A. et al. The genome sequence of Plasmodium knowlesi: the fifth human malaria parasite. Nature. (in press)
29. Hall N., et al. A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses. Science 307 (2005) 82-86
30. Hiller N.L., et al. A host-targeting signal in virulence proteins reveals a secretome in malarial infection. Science 10 (2004) 1934-1937
31. Marti M., et al. Targeting malaria virulence and remodeling proteins to the host erythrocyte. Science 10 (2004) 1930-1933
32. Joannin N., et al. Sub-grouping and sub-functionalization of the RIFIN multi-copy protein family. BMC Genomics 9 (2008) 19-33
33. Petter M., et al. Variant proteins of the Plasmodium falciparum RIFIN family show distinct subcellular localization and developmental expression patterns. Mol. Biochem. Parasitol. 156 (2007) 51-61
34. Winter G., et al. SURFIN is a polymorphic antigen expressed on Plasmodium falciparum merozoites and infected erythrocytes. J. Exp. Med. 201 (2005) 1853-1863
35. Sam-Yellowe T.Y., et al. A Plasmodium gene family encoding Maurer's cleft membrane proteins: structural properties and expression profiling. Genome Res. 14 (2004) 1052-1059
36. Su X.Z., et al. The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes. Cell 82 (1995) 89-100
37. Anstey N.M., et al. Lung injury in vivax malaria: pathophysiological evidence for pulmonary vascular sequestration and posttreatment alveolar-capillary inflammation. J. Infect. Dis. 195 (2007) 589-596
38. Barnwell J.W., et al. Splenic requirement for antigenic variation and expression of the variant antigen on the erythrocyte membrane in cloned Plasmodium knowlesi malaria. Infect. Immun. 40 (1983) 985-994
39. Hommel M., et al. Surface alterations of erythrocytes in Plasmodium falciparum malaria. Antigenic variation, antigenic diversity, and the role of the spleen. J. Exp. Med. 157 (1983) 1137-1148
40. David P.H., et al. Parasite sequestration in Plasmodium falciparum malaria: spleen and antibody modulation of cytoadherence of infected erythrocytes. Proc. Natl. Acad. Sci. U. S. A. 80 (1983) 5075-5079
41. Handunnetti S.M., et al. Antigenic variation of cloned Plasmodium fragile in its natural host Macaca sinica. Sequential appearance of successive variant antigenic types. J. Exp. Med. 165 (1987) 1269-1283
42. Gilks C.F., et al. Relationships between sequestration, antigenic variation and chronic parasitism in Plasmodium chabaudi chabaudi - a rodent malaria model. Parasite Immunol. 12 (1990) 45-64
43. Demar M., et al. Plasmodium falciparum malaria in splenectomized patients: two case reports in French Guiana and a literature review. Am. J. Trop. Med. Hyg. 71 (2004) 290-293
44. Tablin F., et al. The microanatomy of the mammalian spleen: mechanisms of splenic clearance. In: Bowdler A.J. (Ed). The Complete Spleen. (2002), Humana Press 11-22
45. Suwanarusk R., et al. The deformability of red blood cells parasitized by Plasmodium falciparum and P. vivax. J. Infect. Dis. 189 (2004) 190-194
46. Schaecher K., et al. Genome-wide expression profiling in malaria infection reveals transcriptional changes associated with lethal and nonlethal outcomes. Infect. Immun. 73 (2005) 6091-6100
47. Shi Q., et al. Expression, localization, and erythrocyte binding activity of Plasmodium yoelii merozoite surface protein-8. Mol. Biochem. Parasitol. 149 (2006) 231-241
48. Rosanas-Urgell A., et al. Molecular basis for the establishment of chronic infections in reticulocyte-prone non-lethal Plasmodium vivax malaria. Int. J. Parasitol. 38 (2008) S27
49. Buffet P.A., et al. Ex vivo perfusion of human spleens maintains clearing and processing functions. Blood 1 (2006) 3745-3752
50. Yazdani S.S., et al. Immune responses to asexual blood-stages of malaria parasites. Curr. Mol. Med. 6 (2006) 187-203
51. Nogueira P.A., et al. A reduced risk of infection with Plasmodium vivax and clinical protection against malaria are associated with antibodies against the N terminus but not the C terminus of merozoite surface protein 1. Infect. Immun. 74 (2006) 2726-2733
52. King C.L., et al. Naturally acquired Duffy-binding protein-specific binding inhibitory antibodies confer protection from blood-stage Plasmodium vivax infection. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 8363-8368
53. Tsuboi T., et al. Wheat germ cell-free system-based production of malaria proteins for discovery of novel vaccine candidates. Infect. Immun. 76 (2008) 1702-1708
54. Gray J.C. Profiling the antibody immune response against blood stage malaria vaccine candidates. Clin. Chem. 53 (2007) 1244-1253
55. Mok B.W., et al. Comparative transcriptomal analysis of isogenic Plasmodium falciparum clones of distinct antigenic and adhesive phenotypes. Mol. Biochem. Parasitol. 151 (2007) 184-192
56. Daily J.P., et al. Distinct physiological states of Plasmodium falciparum in malaria-infected patients. Nature 450 (2007) 1091-1095
57. Lovegrove F.E., et al. Simultaneous host and parasite expression profiling identifies tissue-specific transcriptional programs associated with susceptibility or resistance to experimental cerebral malaria. BMC Genomics 22 (2006) 295-311
58. Delahaye N.F., et al. Gene-expression profiling discriminates between cerebral malaria (CM)-susceptible mice and CM-resistant mice. J. Infect. Dis. 15 (2005) 312-321
59. Makobongo M.O., et al. Immunization of Aotus monkeys with recombinant cysteine-rich interdomain region 1α protects against severe disease during Plasmodium falciparum reinfection. J. Infect. Dis. 1 (2006) 731-740
60. Chen Q., et al. Immunization with PfEMP1-DBL1α generates antibodies that disrupt rosettes and protect against the sequestration of Plasmodium falciparum-infected erythrocytes. Vaccine 29 (2004) 2701-2712
61. Rogerson S.J., et al. Malaria in pregnancy: pathogenesis and immunity. Lancet Infect. Dis. 7 (2007) 105-117
62. Udomsangpetch R., et al. Cultivation of Plasmodium vivax. Trends Parasitol. 24 (2008) 85-88
63. Trager W., and Jensen J.B. Human malaria parasites in continuous culture. Science 193 (1976) 673-675
64. Kitchen S.K. The infection of reticulocytes by Plasmodium vivax. Am. J. Trop. Med. Hyg. 18 (1938) 347
65. Cowman A.F., and Crabb B.S. Invasion of red blood cells by malaria parasites. Cell 124 (2006) 755-766
66. Nomura T., et al. Evidence for different mechanisms of chloroquine resistance in two Plasmodium species that cause human malaria. J. Infect. Dis. 183 (2001) 1653-1661
67. Fidock D.A., et al. Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Mol. Cell 6 (2000) 861-871
68. Aikawa M. Morphological changes in erythrocytes induced by malarial parasites. Biol. Cell 64 (1988) 173-181
69. Kilejian A. Characterization of a protein correlated with the production of knob-like protrusions on membranes of erythrocytes infected with Plasmodium falciparum. Proc. Natl. Acad. Sci. U. S. A. 76 (1979) 4650-4653
70. Krotoski W.A. The hypnozoite and malarial relapse. Prog. Clin. Parasitol. 1 (1989) 1-19
71. McCutchan T.F., et al. Evolutionary relatedness of Plasmodium species as determined by the structure of DNA. Science 225 (1984) 808-811
72. Gardner M.J., et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419 (2002) 498-511
73. Carlton J.M., et al. Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii. Nature 419 (2002) 512-519
74. Hu G., et al. Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy. BMC Bioinformatics 8 (2007) 350-363
75. Bozdech Z., et al. The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 16290-16295