Parameters of a dose-response model are on the boundary: What happens with BMDL?

Risk Analysis

Volumn 29, Issue 1, 2009, Pages 18-25

  Kopylev, Leonid ^a   Fox, John ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b NONE

Author keywords

Coverage of BMDL; Log logistic model; Multistage model; One sided confidence intervals; Profile likelihood

Indexed keywords

ANIMALS; BIOASSAY; DISTRIBUTION FUNCTIONS; ENVIRONMENTAL PROTECTION AGENCY; LARGE SCALE SYSTEMS; MAXIMUM LIKELIHOOD ESTIMATION;

COVERAGE OF BMDL; LOG-LOGISTIC MODEL; MULTISTAGE MODEL; ONE-SIDED CONFIDENCE INTERVALS; PROFILE LIKELIHOOD;

ASYMPTOTIC ANALYSIS;

ANIMAL; BENCHMARKING; BIOASSAY; CANCER; DOSE-RESPONSE RELATIONSHIP; MODELING; SPATIAL DISTRIBUTION;

ARTICLE; COMPUTER MODEL; COMPUTER PROGRAM; COMPUTER SIMULATION; CONFIDENCE INTERVAL; GEOGRAPHIC DISTRIBUTION; QUALITY CONTROL; RISK ASSESSMENT; STATISTICAL MODEL;

ALGORITHMS; ANIMALS; BIOLOGICAL ASSAY; CARCINOGENS; COMPUTER SIMULATION; CONFIDENCE INTERVALS; HUMANS; MODELS, STATISTICAL; MONTE CARLO METHOD; NEOPLASMS; REGRESSION ANALYSIS; RISK ASSESSMENT; SOFTWARE;

ANIMALIA;

EID: 58149203688     PISSN: 02724332     EISSN: 15396924     Source Type: Journal    
DOI: 10.1111/j.1539-6924.2008.01125.x     Document Type: Article

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