Artificial vaginocervical stimulation induces a conditioned place preference in female rats

Hormones and Behavior

Volumn 55, Issue 1, 2009, Pages 128-132

  Meerts, Sarah H ^a   Clark, Ann S ^a  

^a Dartmouth College   (United States)

Author keywords

Conditioned place preference; Mating; Sexual behavior; Vaginocervical

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; LONG EVANS RAT; MATING; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; SEXUAL BEHAVIOR; SOCIAL INTERACTION; STIMULATION; UTERINE CERVIX; VAGINA;

ANALYSIS OF VARIANCE; ANIMALS; CERVIX UTERI; CONDITIONING (PSYCHOLOGY); COPULATION; FEMALE; MALE; PHYSICAL STIMULATION; RATS; RATS, LONG-EVANS; SOCIAL BEHAVIOR; SPATIAL BEHAVIOR; VAGINA;

EID: 58149188052     PISSN: 0018506X     EISSN: 10956867     Source Type: Journal    
DOI: 10.1016/j.yhbeh.2008.09.003     Document Type: Article

References (41)

1. Bardo M.T., and Bevins R.A. Conditioned place preference: what does it add to our preclinical understanding of drug reward?. Psychopharmacology (Berl), 153 1 (2000) 31-43
2. Bennett A.L., Blasberg M.E., and Blaustein J.D. Sensory cues mediating mating-induced potentiation of sexual receptivity in female rats. Horm. Behav. 40 1 (2001) 77-83
3. Berkley K.J., Robbins A., and Sato Y. Afferent fibers supplying the uterus in the rat. J. Neurophysiol. 59 1 (1988) 142-163
4. Berkley K.J., Robbins A., and Sato Y. Functional differences between afferent fibers in the hypogastric and pelvic nerves innervating female reproductive organs in the rat. J. Neurophysiol. 69 2 (1993) 533-544
5. Carlezon Jr. W.A. Place conditioning to study drug reward and aversion. Methods Mol. Med. 84 (2003) 243-249
6. Chadha H.K., and Hubscher C.H. Convergence of nociceptive information in the forebrain of female rats: reproductive organ response variations with stage of estrus. Exp. Neurol. 210 2 (2008) 375-387
7. Coopersmith C., Candurra C., and Erskine M.S. Effects of paced mating and intromissive stimulation on feminine sexual behavior and estrus termination in the cycling rat. J. Comp. Psychol. 110 2 (1996) 176-186
8. Coria-Avila G.A., Ouimet A.J., Pacheco P., Manzo J., and Pfaus J.G. Olfactory conditioned partner preference in the female rat. Behav. Neurosci. 119 3 (2005) 716-725
9. Coria-Avila G.A., Gavrila A.M., Boulard B., Charron N., Stanley G., and Pfaus J.G. Neurochemical basis of conditioned partner preference in the female rat: II. Disruption by flupenthixol. Behav. Neurosci. 122 2 (2008) 396-406
10. Coria-Avila G.A., Solomon C.E., Vargas E.B., Lemme I., Ryan R., Menard S., Gavrila A.M., and Pfaus J.G. Neurochemical basis of conditioned partner preference in the female rat: I. Disruption by naloxone. Behav. Neurosci. 122 2 (2008) 385-395
11. Dominguez-Salazar E., Camacho F.J., and Paredes R.G. Prenatal blockade of androgen receptors reduces the number of intromissions needed to induce conditioned place preference after paced mating in female rats. Pharmacol. Biochem. Behav. 81 4 (2005) 871-878
12. Douglas L.A., Varlinskaya E.I., and Spear L.P. Rewarding properties of social interactions in adolescent and adult male and female rats: impact of social versus isolate housing of subjects and partners. Dev. Psychobiol. 45 3 (2004) 153-162
13. Frye C.A., Bayon L.E., Pursnani N.K., and Purdy R.H. The neurosteroids, progesterone and 3alpha, 5alpha-THP, enhance sexual motivation, receptivity, and proceptivity in female rats. Brain Res. 808 1 (1998) 72-83
14. Gans S., and Erskine M.S. Effects of neonatal testosterone treatment on pacing behaviors and development of a conditioned place preference. Horm. Behav. 44 4 (2003) 354-364
15. Garcia Horsman P., and Paredes R.G. Dopamine antagonists do not block conditioned place preference induced by paced mating behavior in female rats. Behav. Neurosci. 118 2 (2004) 356-364
16. Guarraci F.A., and Clark A.S. Ibotenic acid lesions of the medial preoptic area disrupt the expression of partner preference in sexually receptive female rats. Brain Res. 1076 1 (2006) 163-170
17. Hardy D.F., and Debold J.F. Effects of mounts without intromission upon the behavior of female rats during the onset of estrogen-induced heat. Physiol. Behav. 7 4 (1971) 643-645
18. Hubscher C.H. Estradiol-associated variation in responses of rostral medullary neurons to somatovisceral stimulation. Exp. Neurol. 200 1 (2006) 227-239
19. Jenkins W.J., and Becker J.B. Female rats develop conditioned place preferences for sex at their preferred interval. Horm. Behav. 43 4 (2003) 503-507
20. Kohlert J.G., and Cappellini C. Female Syrian Hamsters Failed to Condition a Place Preference to the Sight and Smell of a Male Hamster. Program No. 938.3. Neuroscience Meeting Planner (2007), Society for Neuroscience, San Diego, CA Online
21. Kohlert J.G., and Olexa N. The role of vaginal stimulation for the acquisition of conditioned place preference in female Syrian hamsters. Physiol. Behav. 84 1 (2005) 135-139
22. Komisaruk B.R., Adler N.T., and Hutchison J. Genital sensory field: enlargement by estrogen treatment in female rats. Science 178 67 (1972) 1295-1298
23. Madlafousek J., and Hlinak Z. Sexual behavior of the female laboratory rat: inventory, patterning and measurement. Behavior 63 (1977) 129-174
24. Martinez I., and Paredes R.G. Only self-paced mating is rewarding in rats of both sexes. Horm. Behav. 40 4 (2001) 510-517
25. Meerts S.H., and Clark A.S. Female rats exhibit a conditioned place preference for nonpaced mating. Horm. Behav. 51 1 (2007) 89-94
26. Meisel R.L., and Joppa M.A. Conditioned place preference in female hamsters following aggressive or sexual encounters. Physiol. Behav. 56 5 (1994) 1115-1118
27. Meisel R.L., Joppa M.A., and Rowe R.K. Dopamine receptor antagonists attenuate conditioned place preference following sexual behavior in female Syrian hamsters. Eur. J. Pharmacol. 309 1 (1996) 21-24
28. Oldenburger W.P., Everitt B.J., and de Jonge F.H. Conditioned place preference induced by sexual interaction in female rats. Horm. Behav. 26 2 (1992) 214-228
29. Paredes R.G., and Alonso A. Sexual behavior regulated (paced) by the female induces conditioned place preference. Behav. Neurosci. 111 1 (1997) 123-128
30. Paredes R.G., and Agmo A. Has dopamine a physiological role in the control of sexual behavior? A critical review of the evidence. Prog. Neurobiol. 73 3 (2004) 179-226
31. Paredes R.G., and Martinez I. Naloxone blocks place preference conditioning after paced mating in female rats. Behav. Neurosci. 115 6 (2001) 1363-1367
32. Paredes R.G., and Vazquez B. What do female rats like about sex? Paced mating. Behav. Brain Res. 105 1 (1999) 117-127
33. Peters L.C., Kristal M.B., and Komisaruk B.R. Sensory innervation of the external and internal genitalia of the female rat. Brain Res. 408 1-2 (1987) 199-204
34. Pfaus J.G., Kleopoulos S.P., Mobbs C.V., Gibbs R.B., and Pfaff D.W. Sexual stimulation activates c-fos within estrogen-concentrating regions of the female rat forebrain. Brain Res. 624 1-2 (1993) 253-267
35. Pfaus J.G., Manitt C., and Coopersmith C.B. Effects of pelvic, pudendal, or hypogastric nerve cuts on Fos induction in the rat brain following vaginocervical stimulation. Physiol. Behav. 89 5 (2006) 627-636
36. Quysner A., and Blaustein J.D. A dopamine antagonist blocks vaginocervical stimulation-induced neuronal responses in the rat forebrain. Brain Res. 921 1-2 (2001) 173-182
37. Ross E.L., Komisaruk B.R., and O'Donnell D. Evidence that probing the vaginal cervix is analgesic in rats, using an operant paradigm. J. Comp. Physiol. Psychol. 93 2 (1979) 330-336
38. Rowe D.W., and Erskine M.S. c-Fos proto-oncogene activity induced by mating in the preoptic area, hypothalamus and amygdala in the female rat: role of afferent input via the pelvic nerve. Brain Res. 621 1 (1993) 25-34
39. Tetel M.J., Getzinger M.J., and Blaustein J.D. Fos expression in the rat brain following vaginal-cervical stimulation by mating and manual probing. J. Neuroendocrinol. 5 4 (1993) 397-404
40. Walker Q.D., Nelson C.J., Smith D., and Kuhn C.M. Vaginal lavage attenuates cocaine-stimulated activity and establishes place preference in rats. Pharmacol. Biochem. Behav. 73 4 (2002) 743-752
41. Wersinger S.R., Baum M.J., and Erskine M.S. Mating-induced FOS-like immunoreactivity in the rat forebrain: a sex comparison and a dimorphic effect of pelvic nerve transection. J. Neuroendocrinol. 5 5 (1993) 557-568