Successful treatment of refractory polymyositis with the immunosuppressant mizoribine: Case report

Clinical Rheumatology

Volumn 28, Issue 2, 2009, Pages 227-229

  Suwa, A ^a   Hirakata, M ^b   Kaneko, Y ^b   Sato, S ^b   Suzuki, Y ^a   Kuwana, M ^b  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Glucocorticoid; Immunosuppression; Mizoribine; Polymyositis; Therapy

Indexed keywords

ACETYLSALICYLIC ACID; ANTINUCLEAR ANTIBODY; CREATINE KINASE MB; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLYCEROL; HEPARIN; INSULIN; JO 1 ANTIBODY; MIZORIBINE; MUSCLE ENZYME; OZAGREL; PREDNISOLONE; RHEUMATOID FACTOR; SALAZOSULFAPYRIDINE; STEROID;

ACUTE HEART INFARCTION; ADULT; ANGIOCARDIOGRAPHY; ARTICLE; BRAIN INFARCTION; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DIABETES MELLITUS; DIFFUSION WEIGHTED IMAGING; DISEASE EXACERBATION; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG MEGADOSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSARTHRIA; ELECTROCARDIOGRAPHY; ELECTROMYOGRAPHY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GLUCOSE BLOOD LEVEL; HEART EJECTION FRACTION; HEMIPLEGIA; HUMAN; INTERSTITIAL PNEUMONIA; JAPANESE; LYMPHOCYTIC INFILTRATION; MUSCLE BIOPSY; MUSCLE WEAKNESS; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; POLYMYOSITIS; PRIORITY JOURNAL; RAYNAUD PHENOMENON; RHEUMATOID ARTHRITIS; ST SEGMENT ELEVATION; T WAVE INVERSION; THORAX PAIN; THORAX RADIOGRAPHY;

CEREBRAL INFARCTION; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMYOSITIS; RIBONUCLEOSIDES; STEROIDS; TREATMENT OUTCOME;

EID: 58149185084     PISSN: 07703198     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10067-008-1050-6     Document Type: Article

References (15)

1. Bohan A, Peter JB (1975) Polymyositis and dermatomyositis. N Engl J Med 292:344-347
2. Plotz PH, Dalakas M, Leff RL et al (1989) Current concepts in the idiopathic inflammatory myopathies: Polymyositis, dermatomyositis, and related disorders. Ann Intern Med 111:143-157
3. Bunch TW (1981) Prednisone and azathioprine for polymyositis: Long-term follow-up. Arth Rheum 24:45-48
4. Amato AA, Griggs RC (2003) Treatment of inflammatory myopathies. Curr Opin Neurol 16:569-575
5. Joffe MM, Love LA, Leff RL (1993) Drug therapy of idiopathic inflammatory myopathies: Predictors of response to prednisolone, azathioprine, and methotrexate and a comparison of their efficacy. Am J Med 94:379-387
6. Leroy JP, Drosos AA, Yannopoulos DI et al (1990) Intravenous pulse cyclophosphamide therapy in myositis and Sjogren's syndrome. Arth Rheum 33:1579-1581
7. Cushmag KA, Chaimers A, Esdaile JM (2000) Cyclosporine A in the treatment of refractory adult polymyositis/dermatomyositis; population based experience in 6 patients and literature review. J Rheumatol 27:2855-2859
8. Oddis CV, Sciurba FC, Elmagd KA et al (1999) Tacrolimus in refractory polymyositis with interstitial lung disease. Lancet 353:1211-1217
9. Schneider C, Gold R, Schafers M et al (2002) Mycophenolate mofetil in the therapy of refractory polymyositis. Muscle Nerve 25:286-288
10. Mizuno K, Tsujino M, Takada M et al (1974) Studies on bredinin. 1. Isolation, characterization and biological properties. J Antibiot 27:775-782
11. Inou T, Kusaba R, Takahashi I et al (1980) Clinical trial of Bredinin in renal transplantation. Transplant Proc 12:526-528
12. Okamoto K, Ito M, Suzuki Y (1983) Studies on antinephritic effect of mizoribine (p-INN, Bredinin), a new immunosuppressive agent, and azathioprine effect on the nephritic type of anti-GBM nephritis in rats. Japan J Pharmacol 33:541-548
13. Yumura W, Suganuma S, Uchida K et al (2005) Effects of long-term treatment with mizoribine in patients with proliferative lupus nephritis. Clin Nephrol 64(1):28-34
14. Takahashi S, Wakui H, Gustafsson JA et al (2000) Functional interaction of the immunosuppressant mizoribine with 14-3-3 protein. Biochem Biophys Res Com 274:87-92
15. Wada Y, Kubo M (2000) Trials of mizoribine combination therapy for childhood onset autoimmune disorders. Clin Rheumatol Relat Res 12:23-33, in Japanese and English abstract