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Volumn 33, Issue 5, 2008, Pages 1065-1071

PAX4 has the potential to function as a tumor suppressor in human melanoma

Author keywords

Melanoma; PAX4; Tumor suppressor

Indexed keywords

AZACITIDINE; TRANSCRIPTION FACTOR PAX4; TRANSCRIPTION FACTOR PAX9; ENZYME INHIBITOR; HOMEODOMAIN PROTEIN; MESSENGER RNA; PAIRED BOX TRANSCRIPTION FACTOR; PAX4 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 58149184588     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000095     Document Type: Article
Times cited : (19)

References (36)
  • 1
    • 0027170576 scopus 로고
    • Evolution and role of Pax genes
    • Noll M: Evolution and role of Pax genes. Curr Opin Genet Dev 3: 595-605, 1993.
    • (1993) Curr Opin Genet Dev , vol.3 , pp. 595-605
    • Noll, M.1
  • 2
    • 0031239122 scopus 로고    scopus 로고
    • Pax genes and organogenesis
    • Dahl E, Koseki H and Balling R: Pax genes and organogenesis. Bioessays 19: 755-765, 1997.
    • (1997) Bioessays , vol.19 , pp. 755-765
    • Dahl, E.1    Koseki, H.2    Balling, R.3
  • 3
    • 0036139494 scopus 로고    scopus 로고
    • Getting your Pax straight: Pax proteins in development and disease
    • Chi N and Epstein JA: Getting your Pax straight: pax proteins in development and disease. Trends Genet 18: 41-47, 2002.
    • (2002) Trends Genet , vol.18 , pp. 41-47
    • Chi, N.1    Epstein, J.A.2
  • 5
    • 0027393598 scopus 로고
    • A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNAtranscripts in the splotch (Sp) mouse mutant
    • Epstein DJ, Vogan KJ, Trasler DG and Gros P: A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNAtranscripts in the splotch (Sp) mouse mutant. Proc Natl Acad Sci USA 90: 532-536, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 532-536
    • Epstein, D.J.1    Vogan, K.J.2    Trasler, D.G.3    Gros, P.4
  • 6
    • 0028966947 scopus 로고
    • Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux
    • Sanyanusin P, Schimmenti LA, McNoe LA, et al: Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux. Nat Genet 9: 358-364, 1995.
    • (1995) Nat Genet , vol.9 , pp. 358-364
    • Sanyanusin, P.1    Schimmenti, L.A.2    McNoe, L.A.3
  • 7
    • 0028074973 scopus 로고
    • PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects
    • Glaser T, Jepeal L, Edwards JG, Young SR, Favor J and Maas RL: PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects. Nat Genet 7: 463-471, 1994.
    • (1994) Nat Genet , vol.7 , pp. 463-471
    • Glaser, T.1    Jepeal, L.2    Edwards, J.G.3    Young, S.R.4    Favor, J.5    Maas, R.L.6
  • 8
    • 0027521658 scopus 로고
    • Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma
    • Galili N, Davis RJ, Fredericks WJ, et al: Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nat Genet 5: 230-235, 1993.
    • (1993) Nat Genet , vol.5 , pp. 230-235
    • Galili, N.1    Davis, R.J.2    Fredericks, W.J.3
  • 9
    • 0027366917 scopus 로고
    • Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma
    • Shapiro DN, Sublett JE, Li B, Downing JR and Naeve CW: Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma. Cancer Res 53: 5108-5112, 1993.
    • (1993) Cancer Res , vol.53 , pp. 5108-5112
    • Shapiro, D.N.1    Sublett, J.E.2    Li, B.3    Downing, J.R.4    Naeve, C.W.5
  • 11
    • 0035875036 scopus 로고    scopus 로고
    • The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case
    • Cazzaniga G, Daniotti M, Tosi S, et al: The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case. Cancer Res 61: 4666-4670, 2001.
    • (2001) Cancer Res , vol.61 , pp. 4666-4670
    • Cazzaniga, G.1    Daniotti, M.2    Tosi, S.3
  • 15
    • 0028123016 scopus 로고
    • Expression of thyroid-specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms
    • Fabbro D, Di Loreto C, Beltrami CA, Belfiore A, Di Lauro R and Damante G: Expression of thyroid-specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms. Cancer Res 54: 4744-4749, 1994.
    • (1994) Cancer Res , vol.54 , pp. 4744-4749
    • Fabbro, D.1    Di Loreto, C.2    Beltrami, C.A.3    Belfiore, A.4    Di Lauro, R.5    Damante, G.6
  • 16
    • 0027252649 scopus 로고
    • The oncogenic potential of Pax genes
    • Maulbecker CC and Gruss P: The oncogenic potential of Pax genes. EMBO J 12: 2361-2367, 1993.
    • (1993) EMBO J , vol.12 , pp. 2361-2367
    • Maulbecker, C.C.1    Gruss, P.2
  • 17
    • 0344255673 scopus 로고    scopus 로고
    • Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival
    • Muratovska A, Zhou C, He S, Goodyer P and Eccles MR: Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival. Oncogene 22: 7989-7997, 2003.
    • (2003) Oncogene , vol.22 , pp. 7989-7997
    • Muratovska, A.1    Zhou, C.2    He, S.3    Goodyer, P.4    Eccles, M.R.5
  • 19
    • 0029834212 scopus 로고    scopus 로고
    • The paired-box transcription factor, PAX2, positively modulates expression of the Wilms' tumor suppressor gene (WT1)
    • Dehbi M, Ghahremani M, Lechner M, Dressler G and Pelletier J: The paired-box transcription factor, PAX2, positively modulates expression of the Wilms' tumor suppressor gene (WT1). Oncogene 13: 447-453, 1996.
    • (1996) Oncogene , vol.13 , pp. 447-453
    • Dehbi, M.1    Ghahremani, M.2    Lechner, M.3    Dressler, G.4    Pelletier, J.5
  • 20
    • 0030661647 scopus 로고    scopus 로고
    • PAX 8 regulates human WT1 transcription through a novel DNA binding site
    • Fraizer GC, Shimamura R, Zhang X and Saunders GF: PAX 8 regulates human WT1 transcription through a novel DNA binding site. J Biol Chem 272: 30678-30687, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 30678-30687
    • Fraizer, G.C.1    Shimamura, R.2    Zhang, X.3    Saunders, G.F.4
  • 21
    • 0028809870 scopus 로고
    • Loss of p53 function through PAX-mediated transcriptional repression
    • Stuart ET, Haffner R, Oren M and Gruss P: Loss of p53 function through PAX-mediated transcriptional repression. EMBO J 14: 5638-5645, 1995.
    • (1995) EMBO J , vol.14 , pp. 5638-5645
    • Stuart, E.T.1    Haffner, R.2    Oren, M.3    Gruss, P.4
  • 22
    • 0036398147 scopus 로고    scopus 로고
    • Transduction of HOXD3-antisense into human melanoma cells results in decreased invasive and motile activities
    • Okubo Y, Hamada J, Takahashi Y, et al: Transduction of HOXD3-antisense into human melanoma cells results in decreased invasive and motile activities. Clin Exp Metastasis 19: 503-511, 2002.
    • (2002) Clin Exp Metastasis , vol.19 , pp. 503-511
    • Okubo, Y.1    Hamada, J.2    Takahashi, Y.3
  • 24
    • 9144236859 scopus 로고    scopus 로고
    • Expression profiles of 39 HOX genes in normal human adult organs and anaplastic thyroid cancer cell lines by quantitative real-time RT-PCR system
    • Takahashi Y, Hamada J, Murakawa K, et al: Expression profiles of 39 HOX genes in normal human adult organs and anaplastic thyroid cancer cell lines by quantitative real-time RT-PCR system. Exp Cell Res 293: 144-153, 2004.
    • (2004) Exp Cell Res , vol.293 , pp. 144-153
    • Takahashi, Y.1    Hamada, J.2    Murakawa, K.3
  • 25
    • 30144439616 scopus 로고    scopus 로고
    • A PANorama of PAX genes in cancer and development
    • Robson EJ, He SJ and Eccles MR: A PANorama of PAX genes in cancer and development. Nat Rev Cancer 6: 52-62, 2006.
    • (2006) Nat Rev Cancer , vol.6 , pp. 52-62
    • Robson, E.J.1    He, S.J.2    Eccles, M.R.3
  • 26
  • 28
    • 0029082823 scopus 로고
    • Expression of Pax-2 in human renal cell carcinoma and growth inhibition by antisense oligonucleotides
    • Gnarra JR and Dressler GR: Expression of Pax-2 in human renal cell carcinoma and growth inhibition by antisense oligonucleotides. Cancer Res 55: 4092-4098, 1995.
    • (1995) Cancer Res , vol.55 , pp. 4092-4098
    • Gnarra, J.R.1    Dressler, G.R.2
  • 29
    • 0029756801 scopus 로고    scopus 로고
    • PAX8-mediated activation of the wt1 tumor suppressor gene
    • Dehbi M and Pelletier J: PAX8-mediated activation of the wt1 tumor suppressor gene. EMBO J 15: 4297-4306, 1996.
    • (1996) EMBO J , vol.15 , pp. 4297-4306
    • Dehbi, M.1    Pelletier, J.2
  • 30
    • 0041333109 scopus 로고    scopus 로고
    • The expression PAX6, PTEN, vascular endothelial growth factor, and epidermal growth factor receptor in gliomas: Relationship to tumor grade and survival
    • Zhou YH, Tan F, Hess KR and Yung WK: The expression PAX6, PTEN, vascular endothelial growth factor, and epidermal growth factor receptor in gliomas: relationship to tumor grade and survival. Clin Cancer Res 9: 3369-3375, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 3369-3375
    • Zhou, Y.H.1    Tan, F.2    Hess, K.R.3    Yung, W.K.4
  • 31
    • 20144379648 scopus 로고    scopus 로고
    • PAX6 suppresses growth human glioblastoma cells
    • Zhou YH, Wu X, Tan F, et al: PAX6 suppresses growth human glioblastoma cells. J Neurooncol 71: 223-229, 2005.
    • (2005) J Neurooncol , vol.71 , pp. 223-229
    • Zhou, Y.H.1    Wu, X.2    Tan, F.3
  • 32
    • 0034003392 scopus 로고    scopus 로고
    • Pax genes and the differentiation of hormone-producing endocrine cells in the pancreas
    • Dohrmann C, Gruss P and Lemaire L: Pax genes and the differentiation of hormone-producing endocrine cells in the pancreas. Mech Dev 92: 47-54, 2000.
    • (2000) Mech Dev , vol.92 , pp. 47-54
    • Dohrmann, C.1    Gruss, P.2    Lemaire, L.3
  • 33
    • 0030897629 scopus 로고    scopus 로고
    • Sosa-Pineda B, Chowdhury K, Torres M, Oliver G and Gruss The Pax4 gene is essential for differentiation of insulin-producing α-cells in the mammalian pancreas. Nature 386: 399-402, 1997.
    • Sosa-Pineda B, Chowdhury K, Torres M, Oliver G and Gruss The Pax4 gene is essential for differentiation of insulin-producing α-cells in the mammalian pancreas. Nature 386: 399-402, 1997.
  • 34
    • 0030914931 scopus 로고    scopus 로고
    • Pax6 is required for differentiation of glucagons-producing α-cells in mouse pancreas
    • St-Onge L, Sosa-Pineda B, Chowdhury K, Mansouri A and Gruss P: Pax6 is required for differentiation of glucagons-producing α-cells in mouse pancreas. Nature 387: 406-409, 1997.
    • (1997) Nature , vol.387 , pp. 406-409
    • St-Onge, L.1    Sosa-Pineda, B.2    Chowdhury, K.3    Mansouri, A.4    Gruss, P.5
  • 35
    • 0032457472 scopus 로고    scopus 로고
    • Comparison of genetic profiles between primary melanomas and their metastases reveals genetic alterations and clonal evolution during progression
    • Morita R, Fujimoto A, Hatta N, Takehara K and Takata M: Comparison of genetic profiles between primary melanomas and their metastases reveals genetic alterations and clonal evolution during progression. J Invest Dermatol 111: 919-924, 1998.
    • (1998) J Invest Dermatol , vol.111 , pp. 919-924
    • Morita, R.1    Fujimoto, A.2    Hatta, N.3    Takehara, K.4    Takata, M.5
  • 36
    • 0027980907 scopus 로고
    • Comparative genomic hybridization in the detection of DNA copy number abnormalities in uveal melanoma
    • Gordon KB, Thompson CT, Char DH, O'Brien JM, Kroll S, Ghazvini S and Gray JW: Comparative genomic hybridization in the detection of DNA copy number abnormalities in uveal melanoma. Cancer Res 54: 4764-4768, 1994.
    • (1994) Cancer Res , vol.54 , pp. 4764-4768
    • Gordon, K.B.1    Thompson, C.T.2    Char, D.H.3    O'Brien, J.M.4    Kroll, S.5    Ghazvini, S.6    Gray, J.W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.