Defining and Reporting Erectile Function Outcomes After Radical Prostatectomy: Challenges and Misconceptions

Journal of Urology

Volumn 181, Issue 2, 2009, Pages 462-471

  Mulhall, John P ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

erectile dysfunction; phosphodiesterase inhibitors; prostatectomy; questionnaires; research design

Indexed keywords

PHOSPHODIESTERASE V INHIBITOR; PLACEBO; SILDENAFIL;

CLINICAL TRIAL; DEMOGRAPHY; DISEASE ASSOCIATION; ERECTILE DYSFUNCTION; FUNCTIONAL STATUS; HUMAN; INCIDENCE; PENIS ERECTION; POPULATION RESEARCH; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSTATECTOMY; QUESTIONNAIRE; REVIEW;

AGED; ERECTILE DYSFUNCTION; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PROSTATECTOMY; PROSTATIC NEOPLASMS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

EID: 58149178533     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2008.10.047     Document Type: Review

References (56)

1. Fowler Jr. F.J., Barry M.J., Lu-Yao G., Roman A., Wasson J., and Wennberg J.E. Patient-reported complications and follow-up treatment after radical prostatectomy. The National Medicare Experience: 1988-1990 (updated June 1993). Urology 42 (1993) 622
2. Kundu S.D., Roehl K.A., Eggener S.E., Antenor J.A., Han M., and Catalona W.J. Potency, continence and complications in 3,477 consecutive radical retropubic prostatectomies. J Urol 172 (2004) 2227
3. Litwin M.S., Flanders S.C., Pasta D.J., Stoddard M.L., Lubeck D.P., and Henning J.M. Sexual function and bother after radical prostatectomy or radiation for prostate cancer: multivariate quality-of-life analysis from CaPSURE. Cancer of the Prostate Strategic Urologic Research Endeavor. Urology 54 (1999) 503
4. Rabbani F., Stapleton A.M., Kattan M.W., Wheeler T.M., and Scardino P.T. Factors predicting recovery of erections after radical prostatectomy. J Urol 164 (2000) 1929
5. Rozet F., Galiano M., Cathelineau X., Barret E., Cathala N., and Vallancien G. Extraperitoneal laparoscopic radical prostatectomy: a prospective evaluation of 600 cases. J Urol 174 (2005) 908
6. Stanford J.L., Feng Z., Hamilton A.S., Gilliland F.D., Stephenson R.A., Eley J.W., et al. Urinary and sexual function after radical prostatectomy for clinically localized prostate cancer: the Prostate Cancer Outcomes Study. JAMA 283 (2000) 354
7. Walsh P.C., Marschke P., Ricker D., and Burnett A.L. Patient-reported urinary continence and sexual function after anatomic radical prostatectomy. Urology 55 (2000) 58
8. Hoffman R.M., Barry M.J., Stanford J.L., Hamilton A.S., Hunt W.C., and Collins M.M. Health outcomes in older men with localized prostate cancer: results from the Prostate Cancer Outcomes Study. Am J Med 119 (2006) 418
9. Menon M., Tewari A., Baize B., Guillonneau B., and Vallancien G. Prospective comparison of radical retropubic prostatectomy and robot-assisted anatomic prostatectomy: the Vattikuti Urology Institute experience. Urology 60 (2002) 864
10. Rojas-Cruz C., and Mulhall J.P. Sexual health misinformation on robotic prostatectomy websites. J Urol 177 suppl. (2007) 342 abstract 1034
11. Goeman L., Salomon L., La DeTaille A., Vordos D., Hoznek A., Yiou R., et al. Long-term functional and oncological results after retroperitoneal laparoscopic prostatectomy according to a prospective evaluation of 550 patients. World J Urol 24 (2006) 281
12. Menon M., Shrivastava A., Kaul S., Badani K.K., Fumo M., Bhandari M., et al. Vattikuti Institute prostatectomy: contemporary technique and analysis of results. Eur Urol 51 (2007) 648
13. Anastasiadis A.G., Salomon L., Katz R., Hoznek A., Chopin D., and Abbou C.C. Radical retropubic versus laparoscopic prostatectomy: a prospective comparison of functional outcome. Urology 62 (2003) 292
14. Ball A.J., Gambill B., Fabrizio M.D., Davis J.W., Given R.W., Lynch D.F., et al. Prospective longitudinal comparative study of early health-related quality-of-life outcomes in patients undergoing surgical treatment for localized prostate cancer: a short-term evaluation of five approaches from a single institution. J Endourol 20 (2006) 723
15. Begg C.B., Riedel E.R., Bach P.B., Kattan M.W., Schrag D., Warren J.L., et al. Variations in morbidity after radical prostatectomy. N Engl J Med 346 (2002) 1138
16. Bianco Jr. F.J., Kattan M.W., Eastham J.A., Guillonneau B., Scardino P.T., and Mulhall J. Role of surgeon and surgeon volume in erectile function recovery after radical prostatectomy. J Urol 175 suppl. (2006) 70 abstract 212
17. Bianco Jr. F.J., Riedel E.R., Begg C.B., Kattan M.W., and Scardino P.T. Variations among high volume surgeons in the rate of complications after radical prostatectomy: further evidence that technique matters. J Urol 173 (2005) 2099
18. Mulhall J.P., and Morgentaler A. Penile rehabilitation should become the norm for radical prostatectomy patients. J Sex Med 4 (2007) 538
19. Montorsi F., and McCullough A. Efficacy of sildenafil citrate in men with erectile dysfunction following radical prostatectomy: a systematic review of clinical data. J Sex Med 2 (2005) 658
20. Nelson C.J., Choi J.M., Mulhall J.P., and Roth A.J. Determinants of sexual satisfaction in men with prostate cancer. J Sex Med 4 (2007) 1422
21. Kubler H.R., Tseng T.Y., Sun L., Vieweg J., Harris M.J., and Dahm P. Impact of nerve sparing technique on patient self-assessed outcomes after radical perineal prostatectomy. J Urol 178 (2007) 488
22. Kaul S., Savera A., Badani K., Fumo M., Bhandari A., and Menon M. Functional outcomes and oncological efficacy of Vattikuti Institute prostatectomy with Veil of Aphrodite nerve-sparing: an analysis of 154 consecutive patients. BJU Int 97 (2006) 467
23. Ficarra V., Novara G., Galfano A., Stringari C., Baldassarre R., Cavalleri S., et al. Twelve-month self-reported quality of life after retropubic radical prostatectomy: a prospective study with Rand 36-Item Health Survey (Short Form-36). BJU Int 97 (2006) 274
24. Dalkin B.L., Christopher B.A., and Shawler D. Health related quality of life outcomes after radical prostatectomy: attention to study design and the patient-based importance of single-surgeon studies. Urol Oncol 24 (2006) 28
25. Mulhall J., Land S., Parker M., Waters W.B., and Flanigan R.C. The use of an erectogenic pharmacotherapy regimen following radical prostatectomy improves recovery of spontaneous erectile function. J Sex Med 2 (2005) 532
26. Montorsi F., Salonia A., Suardi N., Gallina A., Zanni G., Briganti A., et al. Improving the preservation of the urethral sphincter and neurovascular bundles during open radical retropubic prostatectomy. Eur Urol 48 (2005) 938
27. Gallo L., Perdona S., Autorino R., Celentano E., Menna L., Di Lorenzo G., et al. Recovery of erection after pelvic urologic surgery: our experience. Int J Impot Res 17 (2005) 484
28. Chien G.W., Mikhail A.A., Orvieto M.A., Zagaja G.P., Sokoloff M.H., Brendler C.B., et al. Modified clipless antegrade nerve preservation in robotic-assisted laparoscopic radical prostatectomy with validated sexual function evaluation. Urology 66 (2005) 419
29. Ahlering T.E., Skarecky D., and Borin J. Impact of cautery versus cautery-free preservation of neurovascular bundles on early return of potency. J Endourol 20 (2006) 586
30. Shimizu T., Hisasue S., Sato Y., Kato R., Kobayashi K., and Tsukamoto T. Erectile dysfunction following nerve-sparing radical retropubic prostatectomy and its treatment with sildenafil. Int J Urol 12 (2005) 552
31. Saranchuk J.W., Kattan M.W., Elkin E., Touijer A.K., Scardino P.T., and Eastham J.A. Achieving optimal outcomes after radical prostatectomy. J Clin Oncol 23 (2005) 4146
32. Korfage I.J., Essink-Bot M.L., Borsboom G.J., Madalinska J.B., Kirkels W.J., Habbema J.D., et al. Five-year follow-up of health-related quality of life after primary treatment of localized prostate cancer. Int J Cancer 116 (2005) 291
33. Penson D.F., McLerran D., Feng Z., Li L., Albertsen P.C., Gilliland F.D., et al. 5-Year urinary and sexual outcomes after radical prostatectomy: results from the prostate cancer outcomes study. J Urol 173 (2005) 1701
34. Karakiewicz P.I., Tanguay S., Kattan M.W., Elhilali M.M., and Aprikian A.G. Erectile and urinary dysfunction after radical prostatectomy for prostate cancer in Quebec: a population-based study of 2415 men. Eur Urol 46 (2004) 188
35. Steineck G., Helgesen F., Adolfsson J., Dickman P.W., Johansson J.E., Norlen B.J., et al. Quality of life after radical prostatectomy or watchful waiting. N Engl J Med 347 (2002) 790
36. Noldus J., Michl U., Graefen M., Haese A., Hammerer P., and Huland H. Patient-reported sexual function after nerve-sparing radical retropubic prostatectomy. Eur Urol 42 (2002) 118
37. Katz R., Salomon L., Hoznek A., de la Taille A., Vordos D., Cicco A., et al. Patient reported sexual function following laparoscopic radical prostatectomy. J Urol 168 (2002) 2078
38. Benoit R.M., Naslund M.J., and Cohen J.K. Complications after radical retropubic prostatectomy in the medicare population. Urology 56 (2000) 116
39. Eastham J.A., Kattan M.W., Riedel E., Begg C.B., Wheeler T.M., Gerigk C., et al. Variations among individual surgeons in the rate of positive surgical margins in radical prostatectomy specimens. J Urol 170 (2003) 2292
40. Rosen R.C., Riley A., Wagner G., Osterloh I.H., Kirkpatrick J., and Mishra A. The International Index of Erectile Function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology 49 (1997) 822
41. Cappelleri J.C., and Rosen R.C. The Sexual Health Inventory for Men (SHIM): a 5-year review of research and clinical experience. Int J Impot Res 17 (2005) 307
42. Catania J.A., Binson D., Canchola J., Pollack L.M., Hauck W., and Coates T.J. Effects of interviewer gender, interviewer choice, and item wording on responses to questions concerning sexual behavior. Public Opin Q 60 (1996) 345
43. Althof S.E., Corty E.W., Levine S.B., Levine F., Burnett A.L., McVary K., et al. EDITS: development of questionnaires for evaluating satisfaction with treatments for erectile dysfunction. Urology 53 (1999) 793
44. Litwin M.S., Hays R.D., Fink A., Ganz P.A., Leake B., and Brook R.H. The UCLA Prostate Cancer Index: development, reliability, and validity of a health-related quality of life measure. Med Care 36 (1998) 1002
45. Wei J.T., Dunn R.L., Litwin M.S., Sandler H.M., and Sanda M.G. Development and validation of the expanded prostate cancer index composite (EPIC) for comprehensive assessment of health-related quality of life in men with prostate cancer. Urology 56 (2000) 899
46. Bennett Jr. N.E., Stasi J., Eastham J.A., Guillonneau B., Scardino P.T., and Mulhall J. The chronology of erectile function loss after radical prostatectomy. J Urol 177 suppl (2007) 285 abstract 856
47. Lindau S.T., Schumm L.P., Laumann E.O., Levinson W., O'Muircheartaigh C.A., and Waite L.J. A study of sexuality and health among older adults in the United States. N Engl J Med 357 (2007) 762
48. Mulhall J. Can penile size be preserved after radical prostatectomy?. Eur Urol 52 (2007) 626
49. NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA 270 (1993) 83
50. Padma-Nathan H., McCullough A., Giuliano F., Bicetre L.K., Toler S.M., Wohlhuter C., et al. Postoperative nightly administration of sildenafil citrate significantly improves the return of normal spontaneous erectile function after bilateral nerve-sparing radical prostatectomy. J Urol 169 suppl. (2003) 375 abstract 1402
51. Montorsi F., Salonia A., Gallina A., Zanni G., Dehò F., Briganti A., et al. There is no significant difference between on-demand PDE5-i vs PDE5-i as rehabilitative treatment in patients treated by bilateral nerve-sparing radical retropubic prostatectomy. J Urol 175 suppl. (2006) 225 abstract 695
52. Montorsi F., Guazzoni G., Strambi L.F., Da Pozzo L.F., Nava L., Barbieri L., et al. Recovery of spontaneous erectile function after nerve-sparing radical retropubic prostatectomy with and without early intracavernous injections of alprostadil: results of a prospective, randomized trial. J Urol 158 (1997) 1408
53. Teloken P., Valenzuela R., Parker M., and Mulhall J. The correlation between erectile function and patient satisfaction. J Sex Med 4 (2007) 472
54. Mulhall J.P., Levine L.A., and Junemann K.P. Erection hardness: a unifying factor for defining response in the treatment of erectile dysfunction. Urology 68 (2006) 17
55. Lowy M., Collins S., Bloch M., Gillman M., Lording D., Sutherland P., et al. Quality of erection questionnaire correlates: change in erection quality with erectile function, hardness, and psychosocial measures in men treated with sildenafil for erectile dysfunction. J Sex Med 4 (2007) 83
56. Goldstein I., Mulhall J.P., Bushmakin A.G., Cappelleri J.C., Hvidsten K., and Symonds T. The Erection Hardness Score and its relationship to successful sexual intercourse. J Sex Med (2008) Epub ahead of print