Targeted deletion of α-adducin results in absent β- and γ-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Blood

Volumn 112, Issue 10, 2008, Pages 4298-4307

  Robledo, Raymond F ^a   Ciciotte, Steven L ^a   Gwynn, Babette ^a   Sahr, Kenneth E ^a   Gilligan, Diana M ^b   Mohandas, Narla ^c   Peters, Luanne L ^a  

^a JACKSON LABORATORY   (United States)

^b PUGET SOUND BLOOD CENTER   (United States)

^c NEW YORK BLOOD CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADDUCIN; ALPHA ADDUCIN; BETA ADDUCIN; GAMMA ADDUCIN; SPECTRIN; TETRAMER; UNCLASSIFIED DRUG; ACTIN; ADD2 PROTEIN, HUMAN; CYTOSKELETON PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SURFACE; CONTROLLED STUDY; ERYTHROCYTE DISORDER; FEMALE; GENE DELETION; HEMOLYTIC ANEMIA; HYDROCEPHALUS; IN VIVO STUDY; KNOCKOUT MOUSE; MALE; MEAN CORPUSCULAR VOLUME; MEMBRANE STABILIZATION; MOUSE; NONHUMAN; OSMOTIC FRAGILITY; PRIORITY JOURNAL; PROTEIN FUNCTION; SPHEROCYTOSIS; THROMBOCYTE; THROMBOCYTE SHAPE; ANIMAL; GENETICS; HEREDITARY HEMOLYTIC ANEMIA; HEREDITARY SPHEROCYTOSIS; METABOLISM; MOUSE MUTANT; PATHOLOGY; PROTEIN QUATERNARY STRUCTURE;

ACTINS; ANEMIA, HEMOLYTIC, CONGENITAL; ANIMALS; BLOOD PLATELETS; CYTOSKELETAL PROTEINS; GENE DELETION; HYDROCEPHALUS; MICE; MICE, KNOCKOUT; OSMOTIC FRAGILITY; PROTEIN STRUCTURE, QUATERNARY; SPECTRIN; SPHEROCYTES; SPHEROCYTOSIS, HEREDITARY;

EID: 58149176138     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-05-156000     Document Type: Article

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