The evaluation of effect of alpha-lipoic acid and vitamin E on the lipid peroxidation, gamma-amino butyric acid and serotonin level in the brain of mice (Mus musculus) acutely intoxicated with lindane

Journal of the Neurological Sciences

Volumn 276, Issue 1-2, 2009, Pages 99-102

  Bist, Renu ^a,b   Bhatt, Devendra Kumar ^b  

^a BANASTHALI UNIVERSITY   (India)

^b University College of Science   (India)

Author keywords

Alpha lipoic acid; Gamma amino butyric acid; Lindane; Lipid peroxidation; Serotonin; Vitamin E

Indexed keywords

4 AMINOBUTYRIC ACID; ALPHA TOCOPHEROL; GLUTATHIONE; LINDANE; SEROTONIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOCTIC ACID;

4 AMINOBUTYRIC ACID BRAIN LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN REGION; CEREBELLUM; CHEMICAL ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; HIPPOCAMPUS; HYPOTHALAMUS; LIPID PEROXIDATION; MALE; MEDULLA OBLONGATA; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OLFACTORY CORTEX; OUTCOME ASSESSMENT; PONS; PRIORITY JOURNAL; SEROTONIN BRAIN LEVEL; SWISS WEBSTER MOUSE;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; GAMMA-AMINOBUTYRIC ACID; INSECTICIDES; LINDANE; LIPID PEROXIDATION; MALE; MICE; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; SEROTONIN; THIOCTIC ACID; VITAMIN E;

EID: 58149174089     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2008.09.008     Document Type: Article

References (32)

1. Reigart R.J., and Roberts J.R. Recognition and management of pesticide poisonings. 5th edition (1999), Medical University of South Carolina
2. Pages N., Martin-Pierre S., Suzanne B., and Francoise G.P. Different aspects of lindane toxicity-effect on reproduction. J Soc Biol 196 (2002) 325-338
3. Aldegunde M., Parafita M., and Fernández M.P. Effect of γ-hexachlorocyclohexane on serotonin metabolism in rat brain. Gen Pharmacol 14 (1983) 303-305
4. Budavari S., O'Neil M.J., and Smith A. The Merck Index (1989), Merck and Co. Inc, Rahway NJ 866-867
5. Bagchi D., Hassoun E.A., Bagchi M., and Stohs S. Protective effects of antioxidants against eldrin-induced hepatic lipid peroxidation, membrane microviscosity DNA damage and excretion of urinary lipid metabolites. Free Radic Biol Med 15 (1993) 217-222
6. Khanna R.N., Das M., and Anand M. Influence of phenobarbitol and CCl4 on the modulation of tissue retention profile of hexachlorocyclohexane in rats. Biomed Environ Sci 15 (2002) 119-129
7. Srinivasan K., and Radhakrishnamurty R. Studies on the distribution of beta and gammaisomers of hexachlorocyclohexane in rat tissues. Environ Sci Health B 18 (1983) 401-418
8. Cotman C.W., and Peterson C. Aging in the nervous system. In: Fleischer S., and Packer L. (Eds). Basic neurochemistry (1989), Academic Press, New York 382-389
9. Solomon L.M., Fahrner L., and West D.P. Gamma benzene hexachloride toxicity. A review. Arch Dermatol 113 (1977) 353-357
10. Baker S.T., and Wilkinson C.F. The effects of pesticides on human health, advances in modern environmental toxicology (1990), Princeton Scientific Publishing Co, Princeton, USA, NJ 18
11. Raps S.P., Lai J.C.K., Hertz L., and Cooper J.L. Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons. Brain Res 493 (1989) 398-401
12. Narahashi T. Neuronal ion channels as the target site of insecticides. Pharmacol Toxicol 78 (1996) 1-14
13. Joy R.M. Mode of action of lindane, dieldrin and related insecticides in the central nervous system. Neurobehav Toxicol Teratol 4 (1982) 813-823
14. Lee S.L., Wang W.W., and Fanburg B. Superoxide as an intermediate signal for serotonin-induced mitogenesis. Free Radic Biol Med 24 (1998) 855-858
15. Aviram M., Cogan U., and Modaky S. Excessive dietary tryptophan enhances plasma lipid peroxidation in rats. Atherosclerosis 88 (1991) 29-34
16. Handelman G.J., Han D., Tritschler H., and Packer L. Alpha-lipoic acid reduction by mammalian cells to the dithiol form, and release into the culture medium. Biochem Pharmacol 47 (1994) 1725-1730
17. Burton G.W., Joyce A., and Ingold K.V. Is vitamin E the only lipid soluble, chain breaking antioxidant in human blood plasma and erythrocyte membrane. Arch Biochem Biophys 221 (1983) 281-290
18. Ellman G.L. Tissue sulfhydryl groups. Arch Biochem Biophys 82 (1959) 70-77
19. Ohkawa H., Ohshi N., and Yagi K. Assay or lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95 (1979) 351-358
20. Graham L.T., and Aprison M.H. Fluorometric determination of aspartate, glutamate, and gamma-aminobutyrate in nerve tissue using enzymic methods. Anal Biochem 15 (1966) 487-497
21. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. The original method for protein estimation. Biol Chem 193 (1951) 265
22. Udenfriend S., Weissbach H., and Clark C.T. The estimation of 5-hydroxytryptamine (serotonin) in biological tissues. J Biol Chem 215 (1955) 337
23. Federer W.T. Experimental design. Theory and application (1977), Oxford and IBH Publishing Company
24. Vohland H.W., Portig J., and Stein K. Neuropharamcological effects of isomers of hexachlorocyclohexane. 1. Protection against pentylenetetrazol-induced convulsions. Toxicol Appl Pharmacol 57 (1981) 425-438
25. Junquiera V.B., Simizu K., Halsema L.V., Koch O.R., Barros S.B., and Videla L.A. Lindane induced oxidative stress. Ι. Time course of changes in hepatic microsomal parameters, antioxidant enzyme, lipid peroxidation indices and morphological characteristics. Xenobiotica 18 (1988) 1297-1304
26. Alsharif N.Z., and Stohs S.J. Oxidative stress induced by TCDD is mediated by the AH receptor complex. The Toxicologist 11 (1991) 1000
27. Halliwell B., and Gutteridge J.M.C. Free Rad Biol Med (1985), Clarendon Press, Oxford
28. Halliwell B., and Gutteridge J.M.C. Lipid peroxidation: a radical chain reaction. Free Rad Biol Med (1989), Clarendon Press, Oxford 188-276
29. Baker M.T., Nelson R.M., and Van Dyke R.A. The formation of chlorobenzene and benzene by reductive metabolism of lindane in rat liver microsomes. Arch Biochem Biophys 236 (1985) 506-514
30. Suñol C., Tussell J.M., Gelpi E., and Rodriguez-Farre E. Regional concentrations of GABA, serotonin and noradrenaline in brain at onset of seizures induces by lindane. Neuropharmacology 27 (1988) 677-681
31. Zisterer D.M., Suñol C., Moynagh P.M., Williams D.C., and Rodriguez-Farre E. PK-11195 reduces the brain availability of lindane in rats and the convulsions induced by this neurotoxic agent. Life Sci 57 (1995) 2359-2364
32. Pilot M.A., Thompson H.H., and Zara G.P. Effect of hydroxytryptamine on canine intestinal motility during fasting. J Physiol 343 (1983) 88-99