메뉴 건너뛰기




Volumn 4, Issue 12, 2008, Pages

Tag-trigger-consolidation: A model of early and late long-term-potentiation and depression

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS;

EID: 58149165031     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000248     Document Type: Article
Times cited : (125)

References (59)
  • 1
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • Bliss TVP, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361: 31-39.
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 2
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: An embarassment of riches
    • Malenka RC, Bear MF (2004) LTP and LTD: an embarassment of riches. Neuron 44: 5-21.
    • (2004) Neuron , vol.44 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 3
    • 0015850798 scopus 로고
    • Long-lasting potentation of synaptic transmission in the dendate area of unanaesthetized rabbit following stimulation of the perforant path
    • Bliss T, Gardner-Medwin A (1973) Long-lasting potentation of synaptic transmission in the dendate area of unanaesthetized rabbit following stimulation of the perforant path. J Physiol 232: 357-374.
    • (1973) J Physiol , vol.232 , pp. 357-374
    • Bliss, T.1    Gardner-Medwin, A.2
  • 4
    • 0026579349 scopus 로고
    • Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade
    • Dudek SM, Bear MF (1992) Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. Proc Natl Acad Sci U S A 89: 4363-4367.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 4363-4367
    • Dudek, S.M.1    Bear, M.F.2
  • 5
    • 0025078744 scopus 로고
    • Different voltage dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex
    • Artola A, Bröcher S, Singer W (1990) Different voltage dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex. Nature 347: 69-72.
    • (1990) Nature , vol.347 , pp. 69-72
    • Artola, A.1    Bröcher, S.2    Singer, W.3
  • 6
    • 0031012615 scopus 로고    scopus 로고
    • Regulation of synaptic efficacy by coincidence of postysnaptic AP and EPSP
    • Markram H, Lübke J, Frotscher M, Sakmann B (1997) Regulation of synaptic efficacy by coincidence of postysnaptic AP and EPSP. Science 275: 213-215.
    • (1997) Science , vol.275 , pp. 213-215
    • Markram, H.1    Lübke, J.2    Frotscher, M.3    Sakmann, B.4
  • 7
    • 22144441670 scopus 로고    scopus 로고
    • Graded bidirectional synaptic plasticity is composed of switch-like unitary events
    • O'Connor D, Wittenberg G, Wang SH (2005) Graded bidirectional synaptic plasticity is composed of switch-like unitary events. Proc Natl Acad Sci USA 102: 9679-9684.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 9679-9684
    • O'Connor, D.1    Wittenberg, G.2    Wang, S.H.3
  • 8
    • 0034928712 scopus 로고    scopus 로고
    • Synaptic modification of correlated activity: Hebb's postulate revisited
    • Bi G, Poo M (2001) Synaptic modification of correlated activity: Hebb's postulate revisited. Annu Rev Neurosci 24: 139-166.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 139-166
    • Bi, G.1    Poo, M.2
  • 9
    • 0037884978 scopus 로고    scopus 로고
    • How long will long-term potentiation last?
    • Abraham W (2003) How long will long-term potentiation last? Philos Trans R Soc Lond B Biol Sci 358: 735-744.
    • (2003) Philos Trans R Soc Lond B Biol Sci , vol.358 , pp. 735-744
    • Abraham, W.1
  • 10
    • 0021222306 scopus 로고
    • Anisomycin blocks the late phase of long-term potentiation in the dentate gyrus of freely moving rats
    • Krug M, Lössner B, Ott T (1984) Anisomycin blocks the late phase of long-term potentiation in the dentate gyrus of freely moving rats. Brain Res Bull 13: 39-42.
    • (1984) Brain Res Bull , vol.13 , pp. 39-42
    • Krug, M.1    Lössner, B.2    Ott, T.3
  • 11
    • 20544460467 scopus 로고    scopus 로고
    • Synaptic tagging and cross-tagging: The role of protein kinase Mf in maintaining long-term potentiation but not long-term depression
    • Sajikumar S, Navakkode S, Sacktor T, Frey J (2005) Synaptic tagging and cross-tagging: the role of protein kinase Mf in maintaining long-term potentiation but not long-term depression. J Neurosci 25: 5750-5756.
    • (2005) J Neurosci , vol.25 , pp. 5750-5756
    • Sajikumar, S.1    Navakkode, S.2    Sacktor, T.3    Frey, J.4
  • 12
    • 0031024891 scopus 로고    scopus 로고
    • Synaptic tagging and long-term potentiation
    • Frey U, Morris R (1997) Synaptic tagging and long-term potentiation. Nature 385: 533-536.
    • (1997) Nature , vol.385 , pp. 533-536
    • Frey, U.1    Morris, R.2
  • 13
    • 33845864415 scopus 로고    scopus 로고
    • The late maintenance of hippocampal ltp: Requirements, phases,synaptic tagging, late associativity and implications
    • Reymann K, Frey J (2007) The late maintenance of hippocampal ltp: requirements, phases,synaptic tagging, late associativity and implications. Neuropharmacology 52: 24-40.
    • (2007) Neuropharmacology , vol.52 , pp. 24-40
    • Reymann, K.1    Frey, J.2
  • 14
    • 33748049463 scopus 로고    scopus 로고
    • Storage of spatial information by the maintenance mechanism of LTP
    • Pastalkova E, Serrano P, Pinkhasova D, Wallace E, Fenton A, et al. (2006) Storage of spatial information by the maintenance mechanism of LTP. Science 313: 1141-1144.
    • (2006) Science , vol.313 , pp. 1141-1144
    • Pastalkova, E.1    Serrano, P.2    Pinkhasova, D.3    Wallace, E.4    Fenton, A.5
  • 15
    • 36849154193 scopus 로고
    • Memory and molecular turnover
    • Crick F (1984) Memory and molecular turnover. Nature 312: 101.
    • (1984) Nature , vol.312 , pp. 101
    • Crick, F.1
  • 16
    • 0010424768 scopus 로고
    • A mechanism for memory storage insensitive to molecular turnover: A bistable autophosphorylating kinase
    • Lisman J (1985) A mechanism for memory storage insensitive to molecular turnover: a bistable autophosphorylating kinase. Proc Natl Acad Sci U S A 82: 3055-3057.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 3055-3057
    • Lisman, J.1
  • 17
    • 43449102784 scopus 로고    scopus 로고
    • Glutamate receptor dynamics in dendritic microdomains
    • Newpher TM, Ehlers MD (2008) Glutamate receptor dynamics in dendritic microdomains. Neuron 58: 472-497.
    • (2008) Neuron , vol.58 , pp. 472-497
    • Newpher, T.M.1    Ehlers, M.D.2
  • 18
    • 0031898898 scopus 로고    scopus 로고
    • Cortical plasticity: From synapses to maps
    • Buonomano D, Merzenich M (1998) Cortical plasticity: from synapses to maps. Annu Rev Neurosci 21: 149-186.
    • (1998) Annu Rev Neurosci , vol.21 , pp. 149-186
    • Buonomano, D.1    Merzenich, M.2
  • 19
    • 84973857317 scopus 로고
    • ART 2: Self-organization of stable category recognition codes for analog input patterns
    • Carpenter G, Grossberg S (1987) ART 2: self-organization of stable category recognition codes for analog input patterns. Appl Opt 26: 4919-4930.
    • (1987) Appl Opt , vol.26 , pp. 4919-4930
    • Carpenter, G.1    Grossberg, S.2
  • 21
    • 0001101723 scopus 로고
    • Learning in neural networks with material synapses
    • Amit D, Fusi S (1994) Learning in neural networks with material synapses. Neural Comput 6: 957-982.
    • (1994) Neural Comput , vol.6 , pp. 957-982
    • Amit, D.1    Fusi, S.2
  • 22
    • 13844266723 scopus 로고    scopus 로고
    • Cascade models of synaptically stored memories
    • Fusi S, Drew P, Abbott L (2005) Cascade models of synaptically stored memories. Neuron 45: 599-611.
    • (2005) Neuron , vol.45 , pp. 599-611
    • Fusi, S.1    Drew, P.2    Abbott, L.3
  • 23
    • 0020118274 scopus 로고
    • Neural networks and physical systems with emergent collective computational abilities
    • Hopfield JJ (1982) Neural networks and physical systems with emergent collective computational abilities. Proc Natl Acad Sci U S A 79: 2554-2558.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 2554-2558
    • Hopfield, J.J.1
  • 24
    • 0029821128 scopus 로고    scopus 로고
    • A neuronal learning rule for sub-millisecond temporal coding
    • Gerstner W, Kempter R, van Hemmen J, Wagner H (1996) A neuronal learning rule for sub-millisecond temporal coding. Nature 383: 76-78.
    • (1996) Nature , vol.383 , pp. 76-78
    • Gerstner, W.1    Kempter, R.2    van Hemmen, J.3    Wagner, H.4
  • 26
    • 0033860923 scopus 로고    scopus 로고
    • Competitive Hebbian learning through spike-time-dependent synaptic plasticity
    • Song S, Miller K, Abbott L (2000) Competitive Hebbian learning through spike-time-dependent synaptic plasticity. Nat Neurosci 3: 919-926.
    • (2000) Nat Neurosci , vol.3 , pp. 919-926
    • Song, S.1    Miller, K.2    Abbott, L.3
  • 27
    • 0024341227 scopus 로고
    • A mechanism for Hebb and anti-Hebb processes underlying learning and memory
    • Lisman J (1989) A mechanism for Hebb and anti-Hebb processes underlying learning and memory. Proc Natl Acad Sci U S A 86: 9574-9578.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 9574-9578
    • Lisman, J.1
  • 28
    • 19344362210 scopus 로고    scopus 로고
    • The stability of s stochastic CaMKII switch: Dependenc on the number of enzyme molecules and protein turnover
    • doi:10.1371/journal.pbio.0030107
    • Miller P, Zhabotinsky A, Lisman J, Wang X (2005) The stability of s stochastic CaMKII switch: dependenc on the number of enzyme molecules and protein turnover. PLoS Biol 3: e107. doi:10.1371/journal.pbio.0030107.
    • (2005) PLoS Biol , vol.3
    • Miller, P.1    Zhabotinsky, A.2    Lisman, J.3    Wang, X.4
  • 29
    • 36949013689 scopus 로고    scopus 로고
    • Stdp in a bistable synapse model based on CaMKII and associate signaling pathways
    • e 221. doi:10.1371/journal.pcbi.0030221
    • Graupner M, Brunel N (2007) Stdp in a bistable synapse model based on CaMKII and associate signaling pathways. PLoS Comput Biol 3: e 221. doi:10.1371/journal.pcbi.0030221.
    • (2007) PLoS Comput Biol , vol.3
    • Graupner, M.1    Brunel, N.2
  • 30
    • 34248363969 scopus 로고    scopus 로고
    • Identification of compartment- and process-specific molecules required for 'synaptic tagging' during long-term potentiation and long-term depression in hippocampal CA1
    • Sajikumar S, Navakkode S, Frey J (2007) Identification of compartment- and process-specific molecules required for 'synaptic tagging' during long-term potentiation and long-term depression in hippocampal CA1. J Neurosci 27: 5068-5080.
    • (2007) J Neurosci , vol.27 , pp. 5068-5080
    • Sajikumar, S.1    Navakkode, S.2    Frey, J.3
  • 31
    • 0030857360 scopus 로고    scopus 로고
    • Postsynaptic inhibitors of calcium/ calmodulin-dependent protein kinase type II block induction but not maintenance of pairing induced long-term potentiation
    • Othmakhov N, Griffith L, Lisman J (1997) Postsynaptic inhibitors of calcium/ calmodulin-dependent protein kinase type II block induction but not maintenance of pairing induced long-term potentiation. J Neurosci 17: 5357-5365.
    • (1997) J Neurosci , vol.17 , pp. 5357-5365
    • Othmakhov, N.1    Griffith, L.2    Lisman, J.3
  • 32
    • 2942528888 scopus 로고    scopus 로고
    • Late-associativity, synaptic tagging, and the role of dopamine during LTP and LTD
    • Sajikumar S, Frey J (2004) Late-associativity, synaptic tagging, and the role of dopamine during LTP and LTD. Neurobiol Learn Mem 82: 12-25.
    • (2004) Neurobiol Learn Mem , vol.82 , pp. 12-25
    • Sajikumar, S.1    Frey, J.2
  • 33
    • 0020074887 scopus 로고
    • Theory of the development of neuron selectivity: Orientation specificity and binocular interaction in visual cortex
    • Bienenstock E, Cooper L, Munroe P (1982) Theory of the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex. J Neurosci 2: 32-48.
    • (1982) J Neurosci , vol.2 , pp. 32-48
    • Bienenstock, E.1    Cooper, L.2    Munroe, P.3
  • 34
    • 0040669525 scopus 로고    scopus 로고
    • Hebbian spike-driven synaptic plasticity for learning patterns of mean firing rates
    • Fusi S (2002) Hebbian spike-driven synaptic plasticity for learning patterns of mean firing rates. Biol Cybern 87: 459-470.
    • (2002) Biol Cybern , vol.87 , pp. 459-470
    • Fusi, S.1
  • 35
    • 33748898872 scopus 로고    scopus 로고
    • Triplets of spikes in a model of spike timing-dependent plasticity
    • Pfister JP, Gerstner W (2006) Triplets of spikes in a model of spike timing-dependent plasticity. J Neurosci 26: 9673-9682.
    • (2006) J Neurosci , vol.26 , pp. 9673-9682
    • Pfister, J.P.1    Gerstner, W.2
  • 38
    • 0027517104 scopus 로고
    • Long-term depression of excitatory synaptic transmission and its relationship to long-term potentiation
    • Artola A, Singer W (1993) Long-term depression of excitatory synaptic transmission and its relationship to long-term potentiation. Trends Neurosci 16: 480-487.
    • (1993) Trends Neurosci , vol.16 , pp. 480-487
    • Artola, A.1    Singer, W.2
  • 39
    • 0034175485 scopus 로고    scopus 로고
    • Synaptic activation modulates the induction of bidirectional synaptic changes in adult mouse hippocamus
    • Ngezahayo A, Schachner M, Artola A (2000) Synaptic activation modulates the induction of bidirectional synaptic changes in adult mouse hippocamus. J Neurosci 20: 2451-2458.
    • (2000) J Neurosci , vol.20 , pp. 2451-2458
    • Ngezahayo, A.1    Schachner, M.2    Artola, A.3
  • 40
    • 0025307507 scopus 로고
    • Dopaminergic antagonists prevent long-term maintenance of posttetanic LTP in the CA1 region of rat hippocampal slices
    • Frey U, Schroeder H, Matthies H (1990) Dopaminergic antagonists prevent long-term maintenance of posttetanic LTP in the CA1 region of rat hippocampal slices. Brain Res 522: 69-75.
    • (1990) Brain Res , vol.522 , pp. 69-75
    • Frey, U.1    Schroeder, H.2    Matthies, H.3
  • 41
    • 33749370872 scopus 로고    scopus 로고
    • Molecular switches at the synapse emerge from receptor and kinase traffic
    • doi:10.1371/journal.pcbi. 0010020
    • Hayer A, Bhalla US (2005) Molecular switches at the synapse emerge from receptor and kinase traffic. PLoS Comput Biol 1: e20. doi:10.1371/journal.pcbi. 0010020.
    • (2005) PLoS Comput Biol , vol.1
    • Hayer, A.1    Bhalla, U.S.2
  • 42
    • 27144498986 scopus 로고    scopus 로고
    • Adaptive exponential integrate-and-fire model as an effective description of neuronal activity
    • Brette R, Gerstner W (2005) Adaptive exponential integrate-and-fire model as an effective description of neuronal activity. J Neurophysiol 94: 3637-3642.
    • (2005) J Neurophysiol , vol.94 , pp. 3637-3642
    • Brette, R.1    Gerstner, W.2
  • 43
    • 23044508086 scopus 로고    scopus 로고
    • Dissection of bidirectional synaptic plasticity into saturable unidirectional processes
    • O'Connor D, Wittenberg G, Wang S (2005) Dissection of bidirectional synaptic plasticity into saturable unidirectional processes. J Neurophysiol 94: 1565-1573.
    • (2005) J Neurophysiol , vol.94 , pp. 1565-1573
    • O'Connor, D.1    Wittenberg, G.2    Wang, S.3
  • 44
    • 0032574789 scopus 로고    scopus 로고
    • Differential signaling via the same axon of neocortical pyramidal neurons
    • Markram H, Wu Y, Tosdyks M (1998) Differential signaling via the same axon of neocortical pyramidal neurons. Proc Natl Acad Sci U S A 95: 5323-5328.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5323-5328
    • Markram, H.1    Wu, Y.2    Tosdyks, M.3
  • 45
    • 33646171899 scopus 로고    scopus 로고
    • A model of the roles of essential kinases in the induction and expression of late long-term potentiation
    • Smolen P, Baxter D, Byrne J (2006) A model of the roles of essential kinases in the induction and expression of late long-term potentiation. Biophys J 90: 2760-2775.
    • (2006) Biophys J , vol.90 , pp. 2760-2775
    • Smolen, P.1    Baxter, D.2    Byrne, J.3
  • 46
    • 0036513485 scopus 로고    scopus 로고
    • The molecular basis of CaMKII function in synaptic and behavioural memory
    • Lisman J, Schulman H, Cline H (2002) The molecular basis of CaMKII function in synaptic and behavioural memory. Nat Rev Neurosci 3: 175-190.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 175-190
    • Lisman, J.1    Schulman, H.2    Cline, H.3
  • 47
    • 33745597062 scopus 로고    scopus 로고
    • A clustered plasticity model of long-term memory engrams
    • Govindarajan A, Kelleher R, Tonegawa S (2006) A clustered plasticity model of long-term memory engrams. Nat Rev Neurosci 7: 575-583.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 575-583
    • Govindarajan, A.1    Kelleher, R.2    Tonegawa, S.3
  • 48
    • 33847632899 scopus 로고    scopus 로고
    • Optimality model of unsupervised spike-timing dependent plasticity: Synaptic memory and weight distribution
    • Toyoizumi T, Pfister JP, Aihara K, Gerstner W (2007) Optimality model of unsupervised spike-timing dependent plasticity: synaptic memory and weight distribution. Neural Comput 19: 639-671.
    • (2007) Neural Comput , vol.19 , pp. 639-671
    • Toyoizumi, T.1    Pfister, J.P.2    Aihara, K.3    Gerstner, W.4
  • 49
    • 0038561173 scopus 로고    scopus 로고
    • Long-term potentiation: Outstanding questions and attempted synthesis
    • Lisman J (2003) Long-term potentiation: outstanding questions and attempted synthesis. Phil Trans R Soc Lond B: Biol Sci 358: 829-842.
    • (2003) Phil Trans R Soc Lond B: Biol Sci , vol.358 , pp. 829-842
    • Lisman, J.1
  • 50
    • 33645334456 scopus 로고    scopus 로고
    • Neuronal activity determines the protein synthesis dependence of long-term potentiation
    • Fonseca R, Nägerl U, Morris R, Bonhoeffer T (2003) Neuronal activity determines the protein synthesis dependence of long-term potentiation. Nat Neurosci 9: 478-480.
    • (2003) Nat Neurosci , vol.9 , pp. 478-480
    • Fonseca, R.1    Nägerl, U.2    Morris, R.3    Bonhoeffer, T.4
  • 51
    • 6344223400 scopus 로고    scopus 로고
    • Resetting of 'synaptic tags' is time- and activity-dependent in rat hippocampal CA1 in vitro
    • Sajikumar S, Frey J (2004) Resetting of 'synaptic tags' is time- and activity-dependent in rat hippocampal CA1 in vitro. Neuroscience 129: 503-507.
    • (2004) Neuroscience , vol.129 , pp. 503-507
    • Sajikumar, S.1    Frey, J.2
  • 53
    • 0034276719 scopus 로고    scopus 로고
    • Spatial cognition and neuro-mimetic navigation: A model of hippocampal place cell activity
    • Arleo A, Gerstner W (2000) Spatial cognition and neuro-mimetic navigation: a model of hippocampal place cell activity. Biol Cybern 83: 287-299.
    • (2000) Biol Cybern , vol.83 , pp. 287-299
    • Arleo, A.1    Gerstner, W.2
  • 54
    • 33646801243 scopus 로고    scopus 로고
    • Optimal spike-timing dependent plasticity for precise action potential firing in supervised learning
    • Pfister JP, Toyoizumi T, Barber D, Gerstner W (2006) Optimal spike-timing dependent plasticity for precise action potential firing in supervised learning. Neural Comput 18: 1309-1339.
    • (2006) Neural Comput , vol.18 , pp. 1309-1339
    • Pfister, J.P.1    Toyoizumi, T.2    Barber, D.3    Gerstner, W.4
  • 55
    • 34948906745 scopus 로고    scopus 로고
    • Solving the distal reward problem through linkage of STDP and dopamine signaling
    • Izhikevich E (2007) Solving the distal reward problem through linkage of STDP and dopamine signaling. Cereb Cortex 17: 2443-2452.
    • (2007) Cereb Cortex , vol.17 , pp. 2443-2452
    • Izhikevich, E.1
  • 56
    • 55449121121 scopus 로고    scopus 로고
    • Legenstein R, Pecevski D, Maass W (2008) A learning theory for reward-modulated spike-timing-dependent plasticity with application to biofeedback. PLoS Comput Biol 4: e1000180. doi:10.1371/journal.pcbi.1000180.
    • Legenstein R, Pecevski D, Maass W (2008) A learning theory for reward-modulated spike-timing-dependent plasticity with application to biofeedback. PLoS Comput Biol 4: e1000180. doi:10.1371/journal.pcbi.1000180.
  • 57
    • 0030896968 scopus 로고    scopus 로고
    • A neural substrate for prediction and reward
    • Schultz W, Dayan P, Montague R (1997) A neural substrate for prediction and reward. Science 275: 1593-1599.
    • (1997) Science , vol.275 , pp. 1593-1599
    • Schultz, W.1    Dayan, P.2    Montague, R.3
  • 58
    • 34247590346 scopus 로고    scopus 로고
    • (1007) Synergistic requirements for the induction of dopaminergic D1/D5-receptor-mediated LTP in hippocampal slices of rat CA1 in vitro
    • Navakkode S, Sajikumar S, Frey J (1007) Synergistic requirements for the induction of dopaminergic D1/D5-receptor-mediated LTP in hippocampal slices of rat CA1 in vitro. Neuropharmacology 52: 1547-1554.
    • Neuropharmacology , vol.52 , pp. 1547-1554
    • Navakkode, S.1    Sajikumar, S.2    Frey, J.3
  • 59
    • 39149096545 scopus 로고    scopus 로고
    • Dynamic I-V curves are reliable predictors of naturalistic pyramidal-neuron voltage traces
    • Badel L, Lefort S, Brette R, Petersen C, Gerstner W, et al. (2008) Dynamic I-V curves are reliable predictors of naturalistic pyramidal-neuron voltage traces. J Neurophysiol 99: 656-666.
    • (2008) J Neurophysiol , vol.99 , pp. 656-666
    • Badel, L.1    Lefort, S.2    Brette, R.3    Petersen, C.4    Gerstner, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.