Stereological and biochemical analysis of muscular and connective tissue components in the penile corpus cavernosum adjacent to the fibrous plaque of Peyronie's disease

BJU International

Volumn 103, Issue 2, 2009, Pages 212-216

  Costa, Waldemar S ^a   Rebello, Sabrina B ^a   Cardoso, Luiz E M ^a   Cavalcanti, Andre G ^a   Sampaio, Francisco J B ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Collagen; Elastic system fibres; Extracellular matrix; Penis; Peyronie's disease; Smooth muscle

Indexed keywords

COLLAGEN; HYDROXYPROLINE;

ADULT; ARTICLE; AUTOPSY; CHEMICAL ANALYSIS; CLINICAL ARTICLE; CONNECTIVE TISSUE; CONTROLLED STUDY; CORPUS CAVERNOSUM; ERECTILE DYSFUNCTION; HUMAN; HUMAN TISSUE; MALE; MICROPHOTOGRAPHY; PEYRONIE DISEASE; PRIORITY JOURNAL; STEREOMETRY; TUMOR BIOPSY; TUNICA ALBUGINEA;

ADULT; AGED; BIOPSY; CASE-CONTROL STUDIES; COLLAGEN; CONNECTIVE TISSUE; ELASTIC TISSUE; EXTRACELLULAR MATRIX; HUMANS; IMPOTENCE, VASCULOGENIC; MALE; MIDDLE AGED; MUSCLE, SMOOTH; PENILE INDURATION; PENIS;

EID: 58149154802     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2008.08023.x     Document Type: Article

References (30)

1. Smith CJ, McMahon C, Shabsigh R. Peyronie's disease: the epidemiology, aetiology and clinical evaluation of deformity. BJU Int 2005 95 : 729 32
2. Kendirci M, Trost L, Sikka SC, Hellstrom WJ. Diabetes mellitus is associated with severe Peyronie's disease. BJU Int 2007 99 : 383 6
3. Schwarzer U, Sommer F, Klotz T, Braun M, Reifenrath B, Engelmann U. The prevalence of Peyronie's disease: results of a large survey. BJU Int 2001 88 : 727 30
4. El-Sakka AI. Prevalence of Peyronie's disease among patients with erectile dysfunction. Eur Urol 2006 49 : 564 9
5. Gholami SS, Gonzalez-Cadavid NF, Lin CS, Rajfer J, Lue TF. Peyronie's disease: a review. J Urol 2003 169 : 1234 41
6. Somers KD, Dawson DM. Fibrin deposition in Peyronie's disease plaque. J Urol 1997 157 : 311 5
7. Devine CJ Jr, Somers KD, Jordan SG, Schlossberg SM. Proposal: trauma as the cause of the Peyronie's lesion. J Urol 1997 157 : 285 90
8. Akkus E, Carrier S, Baba K et al. Structural alterations in the tunica albuginea of the penis: impact of Peyronie's disease, ageing and impotence. Br J Urol 1997 79 : 47 53
9. El-Sakka AI, Hassan MU, Nunes L, Bhatnagar RS, Yen TS, Lue TF. Histological and ultrastructural alterations in an animal model of Peyronie's disease. Br J Urol 1998 81 : 445 52
10. El-Sakka AI, Hassoba HM, Pillarisetty RJ, Dahiya R, Lue TF. Peyronie's disease is associated with an increase in transforming growth factor-β protein expression. J Urol 1997 158 : 1391 4
11. Haag SM, Hauck EW, Szardening-Kirchner C et al. Alterations in the transforming growth factor (TGF)-β pathway as a potential factor in the pathogenesis of Peyronie's disease. Eur Urol 2007 51 : 255 61
12. Lopez JA, Jarow JP. Penile vascular evaluation of men with Peyronie's disease. J Urol 1993 149 : 53 5
13. Montorsi F, Guazzoni G, Bergamaschi F et al. Vascular abnormalities in Peyronie's disease: the role of color Doppler sonography. J Urol 1994 151 : 373 5
14. Kadioglu A, Oktar T, Kandirali E, Kendirci M, Sanli O, Ozsoy C. Incidentally diagnosed Peyronie's disease in men presenting with erectile dysfunction. Int J Impot Res 2004 16 : 540 3
15. Brant WO, Bella AJ, Garcia MM, Tantiwongse K, Lue TF. Surgical Atlas. Correction of Peyronie's disease: plaque incision and grafting. BJU Int 2006 97 : 1353 60
16. Gundersen HJ, Bagger P, Bendtsen TF et al. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 1988 96 : 857 81
17. Cabral CA, Sampaio FJ, Cardoso LE. Analysis of the modifications in the composition of bladder glycosaminoglycan and collagen as a consequence of changes in sex hormones associated with puberty or oophorectomy in female rats. J Urol 2003 170 : 2512 6
18. Bergman I, Loxley R. The determination of hydroxyproline in urine hydrolysates. Clin Chim Acta 1970 27 : 347 9
19. Sokal RR, Rohlf FJ. Biometry, 3rd edn. New York : W.H. Freeman, 1995 : 887
20. Kadioglu A, Tefekli A, Erol B, Oktar T, Tunc M, Tellaloglu S. A retrospective review of 307 men with Peyronie's disease. J Urol 2002 168 : 1075 9
21. Weidner W, Schroeder-Printzen I, Weiske WH, Vosshenrich R. Sexual dysfunction in Peyronie's disease: an analysis of 222 patients without previous local plaque therapy. J Urol 1997 157 : 325 8
22. Kadioglu A, Tefekli A, Erol H, Cayan S, Kandirali E. Color Doppler ultrasound assessment of penile vascular system in men with Peyronie's disease. Int J Impot Res 2000 12 : 263 7
23. Wespes E, Goes PM, Schiffmann S, Depierreux M, Vanderhaeghen JJ, Schulman CC. Computerized analysis of smooth muscle fibers in potent and impotent patients. J Urol 1991 146 : 1015 7
24. Sattar AA, Merckx LA, Wespes E. Penile electromyography and its smooth muscle content: interpretation of 25 impotent patients. J Urol 1996 155 : 909 12
25. Luangkhot R, Rutchik S, Agarwal V, Puglia K, Bhargava G, Melman A. Collagen alterations in the corpus cavernosum of men with sexual dysfunction. J Urol 1992 148 : 467 71
26. a edn. Rio de Janeiro : Guanabara Koogan, 2004
27. Sattar AA, Wespes E, Schulman CC. Computerized measurement of penile elastic fibres in potent and impotent men. Eur Urol 1994 25 : 142 4
28. Costa WS, Carrerete FB, Horta WG, Sampaio FJ. Comparative analysis of the penis corpora cavernosa in controls and patients with erectile dysfunction. BJU Int 2006 97 : 567 9
29. Iacono F, Barra S, de Rosa G, Boscaino A, Lotti T. Microstructural disorders of tunica albuginea in patients affected by impotence. Eur Urol 1994 26 : 233 9
30. Jevtich MJ, Khawand NY, Vidic B. Clinical significance of ultrastructural findings in the corpora cavernosa of normal and impotent men. J Urol 1990 143 : 289 93