Nanoaggregates of a random amphiphilic polyanion to carry water-insoluble clofazimine in neutral aqueous media

European Journal of Pharmaceutical Sciences

Volumn 36, Issue 2-3, 2009, Pages 345-351

  Hernandez Valdepeña, Israel ^a   Domurado, Martine ^a   Coudane, Jean ^a   Braud, Christian ^a   Baussard, Jean François ^a   Vert, Michel ^a   Domurado, Dominique ^a,b  

^a UNIV MONTPELLIER   (France)

^b INSERM   (France)

Author keywords

Clofazimine; Electrostatic interaction; Lipophilic microdomain; Molecular microencapsulation; Polymeric carrier; Random amphiphilic polyanion; Tuberculosis; Water insoluble drug

Indexed keywords

CLOFAZIMINE; DRUG CARRIER; GANTREZ COPOLYMER; LAURYL ALCOHOL; MANNOSE; MANNOSE RECEPTOR; NANOAGGREGATE; NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; BOVINE TUBERCULOSIS; DRUG SOLUBILITY; LEPROSY; MICROENCAPSULATION; MOUSE; MYCOBACTERIUM BOVIS; NONHUMAN; PRIORITY JOURNAL;

AZO COMPOUNDS; CLOFAZIMINE; DODECANOL; DRUG CARRIERS; HYDROGEN-ION CONCENTRATION; HYDROPHOBICITY; MALEATES; MANNOSE; POLYETHYLENES; POLYMERS; POTENTIOMETRY; SOLUBILITY; STATIC ELECTRICITY; SURFACE-ACTIVE AGENTS; WATER;

EID: 58149151084     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2008.10.008     Document Type: Article

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