The role of animal models in evaluating reasonable safety and efficacy for human trials of cell-based interventions for neurologic conditions

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 1, 2009, Pages 1-9

  Regenberg, Alan ^a   Mathews, Debra J H ^a   Blass, David M ^b,c,r   Bok, Hilary ^a   Coyle, Joseph T ^d   Duggan, Patrick ^a   Faden, Ruth ^a   Finkel, Julia ^a   Gearhart, John D ^a   Hillis, Argye ^e   Hoke, Ahmet ^e   Johnson, Richard ^a   Johnston, Michael ^f   Kahn, Jeffrey ^g   Kerr, Douglas ^a   King, Patricia ^h   Kurtzberg, Joanne ⁱ   Liao, S Matthew ^a,j   McDonald, John W ^f   McKhann, Guy ^a   Nelson, Karin B ^k   Rao, Mahendra ^k   Siegel, Andrew W ^a   Smith, Kirby ^l   Solter, Davor ^m   Song, Hongjun ^a   Sugarman, Jeremy ^a   Vescovi, Angelo ⁿ   Young, Wise ^o   Greely, Henry T ^p   Traystman, Richard J ^q   more..

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c ABARBANEL MENTAL HEALTH CENTER   (Israel)

^d HARVARD MEDICAL SCHOOL   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f KENNEDY KRIEGER INSTITUTE   (United States)

^g UNIVERSITY OF MINNESOTA   (United States)

^h GEORGETOWN UNIVERSITY LAW CENTER   (United States)

ⁱ DUKE UNIVERSITY MEDICAL CENTER   (United States)

^j UNIVERSITY OF OXFORD   (United Kingdom)

^k NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^l INVITROGEN CORPORATION   (United States)

^m NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

ⁿ UNIVERSITY OF MILAN   (Italy)

^o RUTGERS UNIVERSITY   (United States)

^p STANFORD LAW SCHOOL   (United States)

^q UNIVERSITY OF COLORADO   (United States)

^r TEL AVIV UNIVERSITY   (Israel)

more..

Author keywords

Clinical trials; Modeling; Neurologic conditions; Stem and progenitor cells

Indexed keywords

CELL THERAPY; CEREBROVASCULAR ACCIDENT; CLINICAL FEATURE; CLINICAL TRIAL; FOLLOW UP; FOOD AND DRUG ADMINISTRATION; HUMAN; MENTAL DISEASE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; REVIEW; RISK FACTOR; STEM CELL TRANSPLANTATION; STROKE; TREATMENT OUTCOME; TREATMENT RESPONSE; XENOTRANSPLANTATION;

ANIMALS; CLINICAL TRIALS AS TOPIC; HUMANS; MODELS, ANIMAL; MODELS, NEUROLOGICAL; RISK FACTORS; SAFETY MANAGEMENT;

EID: 58149143142     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2008.98     Document Type: Review

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