The composition of alcohol products from markets in Lithuania and Hungary, and potential health consequences: A pilot study

Alcohol and Alcoholism

Volumn 44, Issue 1, 2009, Pages 93-102

  Lachenmeier, Dirk W ^a   Sarsh, Bart ^b   Rehm, Jürgen ^b,c,d  

^a Chemisches und Veterinäruntersuchungsamt ^*  (Germany)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 BUTANOL; ACETALDEHYDE; ACETIC ACID ETHYL ESTER; ALCOHOL; ALUMINUM; ANION; BENZALDEHYDE; BENZYL ACETATE; BENZYL ALCOHOL; BISMUTH; BORON; BUTANOL; CALCIUM; COBALT; COPPER; COUMARIN; FLAVORING AGENT; HEXANOL; LACTIC ACID ETHYL ESTER; LEAD; MAGNESIUM; METHANOL; NICKEL; NITRATE; PENTANOL; POTASSIUM; PROPANOL; SODIUM; URETHAN;

ALCOHOLIC BEVERAGE; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EUROPE; FOOD ANALYSIS; FOOD QUALITY; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUNGARY; LEGAL ASPECT; LITHUANIA; LIVER TOXICITY; MASS SPECTROMETRY; MEDICAL RESEARCH; MORTALITY; PRIORITY JOURNAL; SCREENING TEST; TANDEM MASS SPECTROMETRY; TAX; TOXICOLOGY;

ALCOHOL DRINKING; ALCOHOLIC BEVERAGES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARINS; DRUG CONTAMINATION; ELECTROCHEMISTRY; ETHANOL; FLAVORING AGENTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUNGARY; LITHUANIA; MASS SPECTROMETRY; METHANOL; PILOT PROJECTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; URETHANE; WATER SUPPLY;

EID: 58149138871     PISSN: 07350414     EISSN: 14643502     Source Type: Journal    
DOI: 10.1093/alcalc/agn095     Document Type: Article

References (47)

1. AFC. (2004) Opinion of the scientific panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the commission related to Coumarin. EFSA J 104 1-36.
2. Battaglia R, Conacher HBS, Page BD. (1990) Ethyl carbamate (urethane) in alcoholic beverages and foods: A review. Food Addit Contam 7 477-96.
3. Codex Alimentarius. (1997) Codex general standard for contaminants and toxins in foods (CODEX STAN 193-1995, Rev. 1-1997). www.codexalimentarius.net (31 July 2008, date last accessed).
4. Codex Alimentarius. (1985) General requirements for natural flavourings (CAC/GL 29.1987). www.codexalimentarius.net (31 July 2008, date last accessed).
5. Conacher HBS, Page BD. (1986) Ethyl carbamate in alcoholic beverages: A Canadian case history. In: Proceedings of Euro Food Tox II, 237-42. European Society of Toxicology, Schwerzenbach, Switzerland.
6. Eurobarometer. (2007) Attitudes towards alcohol. http://ec.europa.eu/ health/ph_determinants/life_style/alcohol/documents/ebs272_en.pdf (31 July 2008, date last accessed).
7. European Commission. (2000) Commission Regulation (EC) no. 2870/2000 laying down community reference methods for the analysis of spirits drinks. Official J Eur Communities L333:20-46.
8. European Council. (1988) Council Directive (EEC) no. 88/388 on the approximation of the laws of the Member States relating to flavourings for use in foodstuffs and to source materials for their production. Official J Eur Communities L184:61-6.
9. European Council. (1989) Council Regulation (EEC) no. 1576/89 laying down general rules on the definition, description and presentation of spirit drinks. Official J Eur Communities L160: 1-17.
10. European Council. (1998) Council Directive 98/83/EC on the quality of water intended for human consumption. Official J Eur Communities L330:32-54.
11. European Parliament and Council. (2008) Regulation (EC) no. 110/2008 of the European Parliament and of the Council of 15 January 2008 on the definition, description, presentation, labelling and the protection of geographical indications of spirit drinks and repealing Council Regulation (EEC) no. 1576/89. Official J Eur Union L39:16-54.
12. Ezzati M, Lopez AD, Rodgers A et al. Comparative Risk Assessment Collaborating Group. (2002) Selected major risk factors and global and regional burden of disease. Lancet 360:1347-60.
13. IARC. (1999) Acetaldehyde. In IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 71, Re-evaluation of SomeOrganicChemicals, Hydrazine and Hydrogen Peroxide. Lyon, France: International Agency for Research on Cancer.
14. IARC. (2000) Coumarin. In IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 77, Some Industrial Chemicals. Lyon, France: International Agency for Research on Cancer.
15. IARC. (2007) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 96, Alcoholic Beverage Consumption and Ethyl Carbamate (Urethane). Lyon, France, in press.
16. JECFA. (1997) Summary of Evaluations Performed by the Joint FAO/WHO Expert Committee on Food Additives. Geneva: World Health Organization.
17. Lachenmeier DW. (2007) Rapid quality control of spirit drinks and beer using multivariate data analysis of Fourier transform infrared spectra. Food Chem 101:825-32.
18. Lachenmeier DW, Attig R, Frank W et al. (2003) The use of ion chromatography to detect adulteration of vodka and rum. Eur Food Res Technol 218:105-10.
19. Lachenmeier DW, Emmert J, Kuballa T et al. (2006a) Thujone - cause of absinthism? Forensic Sci Int 158:1-8.
20. Lachenmeier DW, Frank W, Athanasakis C et al. (2004) Absinthe, a spirit drink - its history and future from a toxicological-analytical and food regulatory point of view. Deutsche Lebensmittel-Rundsch 100:117-29.
21. Lachenmeier DW, Frank W, Kuballa T. (2005a) Application of tandem mass spectrometry combined with gas chromatography to the routine analysis of ethyl carbamate in stone-fruit spirits. Rapid Commun Mass Spectrom 19:108-12.
22. Lachenmeier DW, Musshoff F. (2004) Volatile congeners in alcoholic beverages. Retrospective trends, batch comparisons and current concentration ranges. Rechtsmedizin 14:454-62.
23. Lachenmeier DW, Rehm J, Gmel G. (2007) Surrogate alcohol:wHat do we know and where do we go? Alcohol: Clin Exp Res 31:1613-24.
24. Lachenmeier DW, Schehl B, Kuballa T et al. (2005b) Retrospective trends and current status of ethyl carbamate in German stone-fruit spirits. Food Addit Contam 22:397-5.
25. Lachenmeier DW, Schmidt B, Bretschneider T. (2008a) Rapid and mobile brand authentication of vodka using conductivity measurement. Microchimica Acta 160:283-89.
26. Lachenmeier DW, Sohnius E-M. (2008) The role of acetaldehyde outside ethanol metabolism in the carcinogenicity of alcoholic beverages: Evidence from a large chemical survey. Food Chem Toxicol 46 2903-11.
27. Lachenmeier DW, Sohnius E-M, Attig R et al. (2006b) Quantification of selected volatile constituents and anions in Mexican Agave spirits (Tequila, Mezcal, Sotol, Bacanora). J Agric Food Chem 54 3911-15.
28. Lachenmeier DW, Haupt S, Schulz K. (2008b) Defining maximum levels of higher alcohols in alcoholic beverages and surrogate alcohol products. Regul Toxicol Pharmacol 50:313-21.
29. Lake BG. (1999) Coumarin metabolism, toxicity and carcinogenicity: relevance for human risk assessment. Food Chem Toxicol 37 423-53.
30. Lang K, Vali M, Szücs S et al. (2006) The composition of surrogate and illegal alcohol products in Estonia. Alcohol Alcohol 41:446-50.
31. McKee M, Suzcs S, Sarvary A et al. (2005) The composition of surrogate alcohols consumed in Russia. Alcohol: Clin Exp Res 29 1884-88.
32. Nuzhnyi V. (2004) Chemical composition, toxic, and organoleptic properties of noncommercial alcohol samples. In Haworth A, Simpson R (eds). Moonshine Markets. Issues in Unrecorded Alcohol Beverage Production and Consumption. New York: Brunner-Routledge, 177-99.
33. Paine AJ, Dayan AD. (2001) Defining a tolerable concentration of methanol in alcoholic drinks. Hum Exp Toxicol 20:563-68.
34. Pieper HJ, Rau T, Eller T et al. (1987) A speedy method to determine acetaldehyde, with particular consideration being given to quality inspection in the manufacture of fruit spirits. Deutsche Lebensmittel-Rundsch 83:35-1.
35. Popova S, Rehm J, Patra J et al. (2007) Comparing alcohol consumption in central and eastern Europe to other European countries. Alcohol Alcohol 42:465-73.
36. Rehm J. (2007) Alcohol. In Zatonski, W (ed.). Closing the Health Gap in the European Union, Final Report of the HEM Project (Project no 2003121). Warsaw, Poland: The Maria Sklodowska-Curie Memorial, Cancer Center and Institute of Oncology.
37. Rehm J, Rehn N, Room R et al. (2003a) The global distribution of average volume of alcohol consumption and patterns of drinking. Eur Addict Res 9:147-56.
38. Rehm J, Room R, Graham K et al. (2003b) The relationship of average volume of alcohol consumption and patterns of drinking to burden of disease: An overview. Addiction 98:1209-28.
39. Rehm J, Room R, Monteiro M et al. (2004) Alcohol use. In Ezzati M et al. (eds). Comparative Quantification of Health Risks. Global and Regional Burden of Disease Attributable to Selected Major Risk Factors. Vol. 1. 959-1108. Geneva: World Health Organization.
40. Rehm J, Room R, Monteiro M et al. (2003c) Alcohol as a risk factor for global burden of disease. Eur Addict Res 9:157-64.
41. Rehm J, Sulkowska U, Manczuk M et al. (2007) Alcohol accounts for a high proportion of premature mortality in central and eastern Europe. Int J Epidemiol 36:458-67.
42. Sproll C, Ruge W, Andlauer C et al. (2008) HPLC analysis and safety assessment of coumarin in foods. Food Chem 109:462-69.
43. Stickley A, Leinsalu M, Andreev E et al. (2007) Alcohol poisoning in Russia and the countries in the European part of the former Soviet Union, 1970-2002. Eur J Public Health 17:444-49.
44. Szücs S, Sárváry A, McKee M et al. (2005) Could the high level of cirrhosis in central and eastern Europe be due partly to the quality of alcohol consumed? An exploratory investigation. Addiction 100:536-42.
45. Tomkins S, Saburova L, Kiryanov N et al. (2007) Prevalence and socioeconomic distribution of hazardous patterns of alcohol drinking: study of alcohol consumption in men aged 25-54 years in Izhevsk, Russia. Addiction 102:544-53.
46. WHO. (2006) Guidelines for Drinking-Water Quality. Geneva, Switzerland: World Health Organization.
47. Zimmerli B, Schlatter J. (1991) Ethyl carbamate: Analytical methodology, occurrence, formation, biological activity and risk assessment. Mutat Res 259:325-50.