Pharmacokinetics of buprenorphine after single-dose subcutaneous administration in red-eared sliders (Trachemys scripta elegans)

Journal of Zoo and Wildlife Medicine

Volumn 39, Issue 4, 2008, Pages 590-595

  Kummrow, Maya S ^a,c   Tseng, Florina ^a   Hesse, Leah ^b   Court, Michael ^b  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF GUELPH   (Canada)

Author keywords

Buprenorphine; Pharmacokinetics; Red eared slider; Renal portal system; Trachemys scripta elegans

Indexed keywords

BUPRENORPHINE; NARCOTIC ANALGESIC AGENT;

ANIMAL; ANIMAL DISEASE; AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; BLOOD; CROSSOVER PROCEDURE; DOSE RESPONSE; FEMALE; FORELIMB; HINDLIMB; MALE; METABOLISM; METHODOLOGY; RADIOIMMUNOASSAY; RANDOMIZATION; SUBCUTANEOUS DRUG ADMINISTRATION; TURTLE;

ANALGESICS, OPIOID; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; BUPRENORPHINE; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FORELIMB; HINDLIMB; INJECTIONS, SUBCUTANEOUS; MALE; RADIOIMMUNOASSAY; RANDOM ALLOCATION; TURTLES;

ANIMALIA; REPTILIA; TRACHEMYS SCRIPTA ELEGANS;

EID: 58149125410     PISSN: 10427260     EISSN: None     Source Type: Journal    
DOI: 10.1638/2008-0033.1     Document Type: Article

References (24)

1. Brewster, D., M. J. Humphrey, and M. A. McLeavy. 1981. Biliary excretion, metabolism and enterohepatic circulation of buprenorphine. Xenobiotica 11: 189-196.
2. Carpenter, J. W. 2005. Exotic Animal Formulary. Elsevier Saunders. St. Louis, Missouri.
3. Cone, E. J., C. W. Gorodetzky, D. Yousefnejad, W. F. Buchwald, and R. E. Johnson. 1984. The metabolism and excretion of buprenorphine in humans. Drug Metab. Dispos. 12: 577-581.
4. Evans, E. F., J. D. Proctor, M. J. Fratkin, J. Velandia, and A. J. Wasserman. 1975. Blood flow in muscle groups and drug absorption. Clin. Pharmacol. Ther. 17: 44-47.
5. Greenacre, C., J. Paul-Murphy, K. K. Sladky, and T. Storms. 2005. Reptile and Amphibian Analgesia, Roundtable. J. Herpetol. Med. Surg. 15: 24-30.
6. Holz, P., I. K. Barker, J. P. Burger, G. J. Crawshaw, and P. D. Conlon. 1997. The effect of the renal portal system on pharmacokinetic parameters in the red-eared slider (Trachemys scripta elegans). J. Zoo Wild. Med. 28: 386-393.
7. Holz, P., I. K. Barker, G. J. Crawshaw, and H. Dobson. 1997. The anatomy and perfusion of the renal portal system in the red-eared slider (Trachemys scripta elegans). J. Zoo Wild. Med. 28: 378-385.
8. Johnson, R. E., P. J. Fudala, and R. Payne. 2005. Buprenorphine: considerations for pain management. J. Pain Symptom Manage. 29: 297-326.
9. Kanui, T. L., and K. Hole. 1992. Morphine and pethidine antinociception in the crocodile. J. Vet. Pharmacol. Ther. 15: 101-103.
10. Li, X., and D. E. Keith. 1996. Multiple opioid receptor-like genes are identified in diverse vertebrate phyla. FEBS Lett. 397: 25-29.
11. Lorez, H. P., and M. Kemali. 1981. Substance P, met-enkephalin- and somatostatin-like immunoreactivity distribution in the frog spinal cord. Neurosci. Lett. 26: 119-124.
12. Mauk, M. D., and R. D. Olson. 1981. Tonic immobility produces hyperalgesia and antagonizes morphine analgesia. Science 213: 353-354.
13. Mitchiteru, O., K. Hajime, S. Yasufumi, and I. Tatsuji. 1995. Comparative analysis of buprenorphine- and norbuprenorphine-induced analgesic effects based on pharmacokinetic-pharmacodynamic modeling. J. Pharmacol. Exp. Ther. 272: 505-510.
14. Ng, T. B., and W. K. Hon. 1986. Evidence for the presence of adrenocorticotropic and opiate-like hormones in two sea snakes, Hydrophis cyanocinctus and Lapemis hardwickii. Gen. Comp. Endocrinol. 63: 31-37.
15. Paul-Murphy, J., D. B. Brunson, and V. Miletic. 1999. Analgesic effects of butorphanol and buprenorphine in conscious African grey parrots (Psittacus erithacus erithacus and Psittacus erithacus timneh). Am. J. Vet. Res. 60: 1218-1221.
16. Paul-Murphy, J., J. C. Hess, and J. P. Fialkowski. 2004. Pharmacokinetic properties of a single intramuscular dose of buprenorphine in African grey parrots (Psittacus erithacus erithacus). J. Avian Med. Surg. 18: 224-228.
17. Sladky, K. K., V. Miletic, J. Paul-Murphy, M. E. Kinney, R. Dallwig, and S. M. Johnson. 2007. Analgesic efficacy and respiratory effects of butorphanol and morphine in turtles. J. Am. Vet. Med. Assoc. 230: 1356-1362.
18. Stevens, C. W., A. J. Klopp, and A. Facello. 1994. Analgesic potency of mu and kappa opioids after systemic administration in amphibians. J. Pharmacol. Exp. Ther. 269: 1086-1093.
19. Stevens, C. W., and L. C. Newman. 1999. Spinal administration of selective opioid antagonists in amphibians: evidence for an opioid unireceptor. Life Sci. 64: 125-130.
20. Watson, P. J. Q., H. J. McQuay, R. E. S. Bullingham, M. C. Allen, and R. A. Moore. 1982. Single-dose comparison of buprenorphine 0.3 and 0.6 mg i.v. given after operation: clinical effects and plasma concentrations. Br. J. Anaesth. 54: 37-43.
21. Xia, Y., and G. G. Haddad. 2001. Major difference in the expression of delta- and mu-opioid receptors between turtle and rat brain. J. Comp. Neurol. 436: 202-210.
22. Yassen, A., E. Olofsen, A. Dahan, and M. Danhof. 2005. Pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine and fentanyl in rats: role of receptor equilibration kinetics. J. Pharmacol. Exp. Ther. 313: 1136-1149.
23. Yassen, A., E. Olofsen, J. Kan, A. Dahan, and M. Danhof. 2008. Pharmacokinetic-pharmacodynamic modeling of the effectiveness and safety of buprenorphine and fentanyl in rats. Pharm. Res. 25: 183-193.
24. Yassen, A., E. Olofsen, R. Romberg, E. Sarton, M. Danhof, and A. Dahan. 2006. Mechanism-based pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine in healthy volunteers. Anesthesiology 104: 1232-1242.