Pharmacists' interventions for optimization of medication use in nursing homes: A systematic review

Drugs and Aging

Volumn 26, Issue 1, 2009, Pages 37-49

  Verrue, Charlotte L R ^a   Petrovic, Mirko ^b,c   Mehuys, Els ^a   Remon, Jean Paul ^a   Vander Stichele, Robert ^b  

^a GHENT UNIVERSITY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Drug utilisation; Elderly; Pharmaceutical services

Indexed keywords

ACETYLSALICYLIC ACID; ANALGESIC AGENT; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; NEUROLEPTIC AGENT; PSYCHOTROPIC AGENT; WARFARIN;

ACCIDENT PREVENTION; AGED; CASE MANAGEMENT; CLINICAL TRIAL; COST CONTROL; DRUG USE; ELDERLY CARE; FALLING; HEALTH CARE QUALITY; HEART ATRIUM FIBRILLATION; HUMAN; NURSING HOME; OUTCOME ASSESSMENT; PAIN; PATIENT CARE; PHARMACEUTICAL CARE; PHARMACIST; PRESCRIPTION; PRIORITY JOURNAL; REVIEW; ROLE PLAYING; STROKE; SYSTEMATIC REVIEW; TREATMENT PLANNING;

AGED; CONTROLLED CLINICAL TRIALS AS TOPIC; DRUG THERAPY; HEALTH SERVICES FOR THE AGED; HUMANS; NURSING HOMES; PHARMACEUTICAL SERVICES; PHARMACISTS; PROFESSIONAL ROLE;

EID: 58149125234     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/0002512-200926010-00003     Document Type: Review

References (56)

1. Jones D, Poole C. Medicine taking by elderly people: an overview. In: George CF, Woodhouse KW, editors. Drug therapy in old age. Chichester, UK: Wiley and Sons, 1998: 1-22
2. Walley T, Scott AK. Prescribing in the elderly. Postgrad Med J 1995; 71 (838): 466-71
3. Lau DT, Kasper JD, Potter DE, et al. Hospitalisation and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents. Arch Intern Med 2005; 165: 68-74
4. Perri M, Menon AM, Deshpande AD, et al. Adverse outcomes associated with inappropriate drug use in nursing homes. Ann Pharmacother 2005; 39 (3): 405-11
5. Beers MH, Ouslander JG, Fingold SF, et al. Inappropriate medication prescribing in skilled-nursing facilities. Ann Intern Med 1992; 117 (8): 684-9
6. Schmader KE, Hanlon JT, Weinberger M, et al. Appropriateness of medication prescribing in ambulatory elderly patients. J Am Geriatr Soc 1994; 42 (12): 1241-7
7. Gupta S, Rappaport HM, Bennett LT. Inappropriate drug prescribing and related outcomes for elderly Medicaid benefi- ciaries residing in nursing homes. Clin Ther 1996; 18 (1): 183-96
8. Willcox SM, Himmelstein DU, Woolhandler S. Inappropriate drug prescribing for the community-dwelling elderly. JAMA 1994; 272 (4): 292-6
9. Aparasu RR, Sitzman SJ. Inappropriate prescribing for the elderly in the outpatient department setting. Am J Health-Syst Pharm 1999; 56 (5): 433-9
10. Levenson SA, Saffel DA. The consultant pharmacist and the physician in the nursing home: roles, relationships, and a recipe for success. J Med Dir 2007; 8 (1): 55-64
11. Furniss L, Craig SKL, Burns A. Medication use in nursing homes for elderly people. Int J Geriatr Psychiatr 1998; 13 (7): 433-9
12. Simonson W, Feinberg JL. Medication-related problems in the elderly: defining the issues and identifying solutions. Drugs Aging 2005; 22 (7): 559-69
13. Stoudemire A, Smith DA. OBRA regulations and the use of psychotropic drugs in long-term care facilities: impact and implications for geropsychiatric care. Gen Hosp Psychiatry 1996; 18 (2): 77-94
14. Gurwitz JH, Soumerai SB, Avorn J. Improving medication prescribing and utilization in the nursing home. J Am Geriatr Soc 1990; 38 (5): 542-52
15. Kaldy J. Teacher, teacher: when pharmacists embrace their role as educators. Consult Pharm 2008; 23 (2): 100-102, 105-106, 109-10
16. Linnebur SA, O'Connell MB, Wessell AM, et al. Pharmacy practice, research, education, and advocacy for older adults. Pharmacotherapy 2005; 25 (10): 1396-430
17. Cameron KA. Preventing medication-related problems among older Americans. Manag Care Interface 1998; 11 (10): 74-76, 78, 83-5
18. Harjivan C, Lyles A. Improved medication use in long-term care: building on the consultant pharmacist's drug regimen review. Am J Manag Care 2002; 8 (4): 318-26
19. Bootman JL, Harrison DL, Cox ER. The health care cost of drug-related morbidity and mortality in nursing facilities. Arch Intern Med 1997; 157 (18): 2089-96
20. Daschner M, Brownstein S, Cameron KA, et al. Fleetwood phase II tests a new model of long-term care pharmacy. Consult Pharm 2000; 15 (10): 989-1005
21. Christian JB, van Haaren A, Cameron KA, et al. Alternatives for potentially inappropriate medications in the elderly population: treatment algorithms for use in the Fleetwood Phase III study. Consult Pharm 2004; 19 (11): 1011-28
22. Lapane KL, Hiris J, Hughes CM, et al. Development and implementation of pharmaceutical care planning software for nursing homes based on the Fleetwood Model. Am J Health-Syst Pharm 2006; 63 (24): 2483-7
23. Roughead EE, Semple SJ, Gilbert AL. Quality use of medicines in aged-care facilities in Australia. Drugs Aging 2003; 20 (9): 643-53
24. Klepping G. Medication review in elderly care homes. Prim Care Pharm 2000; 1 (4): 105-8
25. Schmidt I, Claesson CB, Westerholm B, et al. The impact of regular multidisciplinary team interventions on psychotropic prescribing in Swedish nursing homes. J Am Geriatr Soc 1998; 46 (1): 77-82
26. Schmidt IK, Claesson CB, Westerholm B, et al. Physician and staff assessments of drug interventions and outcomes in Swedish nursing homes. Ann Pharmacother 1998; 32 (1): 27-32
27. Furniss L, Burns A, Craig SKL, et al. Effects of a pharmacist's medication review in nursing homes: randomised controlled trial. Br J Psychiatry 2000; 176: 563-7
28. Roberts MS, Stokes JA, King MA, et al. Outcomes of a randomized controlled trial of a clinical pharmacy intervention in 52 nursing homes. Br J Clin Pharmacol 2001; 51 (3): 257-65
29. Crotty M, Whitehead C, Rowett D, et al. An outreach intervention to implement evidence based practice in residential care: a randomized controlled trial [ISRCTN67855475]. BMC Health Serv Res 2004; 4 (1): 6
30. Crotty M, Halbert J, Rowett D, et al. An outreach geriatric medication advisory service in residential aged care: a randomised controlled trial of case conferencing. Age Ageing 2004; 33 (6): 612-7
31. Crotty M, Rowett D, Spurling L, et al. Does the addition of a pharmacist transition coordinator improve evidence-based medication management and health outcomes in older adults moving from the hospital to a long-term care facility? Results of a randomized, controlled trial. Am J Geriatr Pharmacother 2004; 2 (4): 257-64
32. Zermansky AG, Alldred DP, Petty DR, et al. Clinical medication review by a pharmacist of elderly people living in care homes: randomised controlled trial. Age Ageing 2006; 35 (6): 586-91
33. King MA, Roberts MS. Multidisciplinary case conference reviews: improving outcomes for nursing home residents, carers and health professionals. Pharm World Sci 2001; 23 (2): 41-5
34. Majumdar SR, Soumerai SB. Why most interventions to improve physician prescribing do not seem to work. Can Med Assoc J 2003; 169 (1): 30-1
35. Handler SM, Wright RM, Ruby CM, et al. Epidemiology of medication-related adverse events in nursing homes. Am J Geriatr Pharmacother 2006; 4 (3): 264-72
36. Nester TM, Hale LS. Effectiveness of a pharmacist-acquired medication history in promoting patient safety. Am J Health-Syst Pharm 2002; 59 (22): 2221-5
37. Bond CA, Raehl CL, Franke T. Clinical pharmacy services, hospital pharmacy staffing, and medication errors in United States hospitals. Pharmacotherapy 2002; 22 (2): 134-47
38. Al-Rashed SA, Wright DJ, Roebuck N, et al. The value of inpatient pharmaceutical counselling to elderly patients prior to discharge. Br J Clin Pharmacol 2002; 54 (6): 657-64
39. Boddy C. Pharmacist involvement with warfarin dosing for inpatients. Pharm World Sci 2001; 23 (1): 31-5
40. Scarsi KK, Fotis MA, Noskin GA. Pharmacist participation in medical rounds reduces medication errors. Am J Health-Syst Pharm 2002; 59 (21): 2089-92
41. Kucukarslan SN, Peters M, Mlynarek M, et al. Pharmacists on rounding teams reduce preventable adverse drug events in hospital general medicine units. Arch Intern Med 2003; 163 (17): 2014-8
42. Bond CA, Raehl CL, Franke T. Clinical pharmacy services and hospital mortality rates. Pharmacotherapy 1999; 19 (5): 556-64
43. Mol PGM, Wieringa JE, NannanPanday PV, et al. Improving compliance with hospital antibiotic guidelines: a time-series intervention analysis. J Antimicrob Chemother 2005; 55 (4): 550-7
44. Schiller DS. Identification, management, and prevention of adverse effects associated with highly active antiretroviral therapy. Am J Health-Syst Pharm 2004; 61 (23): 2507-22
45. Krishnan HS, Schaefer M. Evaluation of the impact of pharmacist's advice giving on the outcomes of self-medication in patients suffering from dyspepsia. Pharm World Sci 2000; 22 (3): 102-8
46. Buurma H, De Smet P, Leufkens HGM, et al. Evaluation of the clinical value of pharmacists' modifications of prescription errors. Br J Clin Pharmacol 2004; 58 (5): 503-11
47. Hawksworth GM, Corlett AJ, Wright DJ, et al. Clinical pharmacy interventions by community pharmacists during the dispensing process. Br J Clin Pharmacol 1999; 47 (6): 695-700
48. Chabot I, Moisan J, Gregoire JP, et al. Pharmacist intervention program for control of hypertension. Ann Pharmacother 2003; 37 (9): 1186-93
49. Saini B, Krass I, Armour C. Development, implementation, and evaluation of a community pharmacy-based asthma care model. Ann Pharmacother 2004; 38 (11): 1954-60
50. MacLaughlin EJ, MacLaughlin AA, Snella KA, et al. Osteoporosis screening and education in community pharmacies using a team approach. Pharmacotherapy 2005; 25 (3): 379-86
51. Jaber LA, Halapy H, Fernet M, et al. Evaluation of a pharmaceutical care model on diabetes management. Ann Pharmacother 1996; 30 (3): 238-43
52. Carter BL, Barnette DJ, Chrischilles E, et al. Evaluation of hypertensive patients after care provided by community pharmacists in a rural setting. Pharmacotherapy 1997; 17 (6): 1274-85
53. Erickson SR, Slaughter R, Halapy H. Pharmacists' ability to influence outcomes of hypertension therapy. Pharmacotherapy 1997; 17 (1): 140-7
54. Solomon DK, Portner TS, Bass GE, et al. Clinical and economic outcomes in the hypertension and COPD arms of a multicenter outcomes study. J Am Pharm Assoc 1998; 38 (5): 574-85
55. Cowper PA, Weinberger M, Hanlon JT, et al. The cost-effectiveness of a clinical pharmacist intervention among elderly outpatients. Pharmacotherapy 1998; 18 (2): 327-32
56. Ellis SL, Carter BL, Malone DC, et al. Clinical and economic impact of ambulatory care clinical pharmacists in management of dyslipidemia in older adults: the IMPROVE study. Pharmacotherapy 2000; 20 (12): 1508-16