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Volumn 39, Issue 2, 2009, Pages 291-298

Efficient synthesis of olmesartan medoxomil, an antihypertensive drug

Author keywords

Angiotensin receptor antagonist; Anti hypertensive; Olmesartan

Indexed keywords

(5 METHY2 OXO 1,3 DIOXOLEN 4 YL) METHYL 4 (1 HYDROXY 1 METHYLETHYL) 2 PROPYL 1 [4 (2 TRITYLTETRAZOL 5 YL)PHENYL]PHENYLMETHYL IMADAZOLE 5 CARBOXYLIC ACID; 2 PROPYLIMIDAZOLE 4,5 DICARBONITRILE; 2 PROPYLIMIDAZOLE 4,5 DICARBOXYLIC ACID; 4 (1 HYDROXY 1 METHYLETHYL) 2 PROPYL 1 [4 (2 TRITYLTETRAZOL 5 YL)PHENYL]PHENYLMETHYL IMADAZOLE 5 CARBOXYLIC ACID; ANTIHYPERTENSIVE AGENT; DIMETHYL 2 PROPYL 1 [4 (2 TRITYLTETRAZOL 5 YL)PHENYL]PHENYLMETHYL IMADAZOLE 4,5 CARBOXYLATE; DIMETHYL 2 PROPYLIMIDAZOLE 4,5 DICARBOXYLATE; METHYL 4 (1 HYDROXY 1 METHYLETHYL) 2 PROPYL 1 [4 (2 TRITYLTETRAZOL 5 YL)PHENYL]PHENYLMETHYL IMADAZOLE 5 CARBOXYLATE; OLMESARTAN; UNCLASSIFIED DRUG;

EID: 58149109058     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910802372558     Document Type: Article
Times cited : (19)

References (5)
  • 1
    • 39849103415 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blocker, olmesartan, restores nocturnal blood pressure decline by enhancing daytime natriuresis
    • Fukuda, M.; Yamanaka, T.; Mizuno, M.; Motokawa, M.; Shirasawa, Y.; Miyagi, S.; Nishio, T.; Yoshida, A.; Kimura, G. Angiotensin II type 1 receptor blocker, olmesartan, restores nocturnal blood pressure decline by enhancing daytime natriuresis. J. Hypertens. 2008, 26, 583-588.
    • (2008) J. Hypertens , vol.26 , pp. 583-588
    • Fukuda, M.1    Yamanaka, T.2    Mizuno, M.3    Motokawa, M.4    Shirasawa, Y.5    Miyagi, S.6    Nishio, T.7    Yoshida, A.8    Kimura, G.9
  • 2
    • 0030049822 scopus 로고    scopus 로고
    • Nonpeptide angiotensin II receptor antagonists: Synthesis, biological activities, and structure-activity relationships of imidazole-5-carboxylic acids bearing alkyl, alkenyl, and hydroxyalkyl substituents at the 4-position and their related compounds
    • Yanagisawa, H.; Amemiya, Y.; Kanazaki, T.; Shimoji, Y.; Fujimoto, K.; Kitahara, Y.; Sada, T.; Mizuno, M.; Ikeda, M.; Miyamoto, S.; Furukawa, Y.; Koike, H. Nonpeptide angiotensin II receptor antagonists: Synthesis, biological activities, and structure-activity relationships of imidazole-5-carboxylic acids bearing alkyl, alkenyl, and hydroxyalkyl substituents at the 4-position and their related compounds. J. Med. Chem. 1996, 39, 323-338.
    • (1996) J. Med. Chem , vol.39 , pp. 323-338
    • Yanagisawa, H.1    Amemiya, Y.2    Kanazaki, T.3    Shimoji, Y.4    Fujimoto, K.5    Kitahara, Y.6    Sada, T.7    Mizuno, M.8    Ikeda, M.9    Miyamoto, S.10    Furukawa, Y.11    Koike, H.12
  • 3
    • 0037224486 scopus 로고    scopus 로고
    • Gardner, S. F.; Franks, A. M. Olmesartan medoxomil: The seventh angiotensin receptor antagonist. Ann. Pharmacother. 2003, 37, 99-105.
    • Gardner, S. F.; Franks, A. M. Olmesartan medoxomil: The seventh angiotensin receptor antagonist. Ann. Pharmacother. 2003, 37, 99-105.
  • 4
    • 58149128327 scopus 로고    scopus 로고
    • Babu, K. S.; Reddy, M. S.; Tagore, A. R.; Reddy, G. S.; Sebastian, S. Process for preparing olmesartan medoxomil. WO 2007/047838 A2, 2007.
    • Babu, K. S.; Reddy, M. S.; Tagore, A. R.; Reddy, G. S.; Sebastian, S. Process for preparing olmesartan medoxomil. WO 2007/047838 A2, 2007.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.