Mechanical strain increases cytokine and chemokine production in bronchial fibroblasts from asthmatic patients

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 64, Issue 1, 2009, Pages 32-39

  Le Bellego, F ^a   Perera, H ^a   Plante, S ^b   Chakir, J ^b   Hamid, Q ^a   Ludwig, M S ^a  

^a MCGILL UNIVERSITY   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Airway remodeling; Interleukin 6; Interleukin 8; Monocyte chemotactic protein 1; Versican

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; VERSICAN;

ADULT; ARTICLE; ASTHMA; BRONCHUS; CELL GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MECHANICAL STRESS; NOSE POLYP; PRIORITY JOURNAL; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

ADOLESCENT; ADULT; ASTHMA; BIOMECHANICS; BRONCHI; CASE-CONTROL STUDIES; CHEMOKINES; CYTOKINES; EXTRACELLULAR MATRIX PROTEINS; FEMALE; FIBROBLASTS; HUMANS; INTERLEUKIN-6; MALE; UP-REGULATION; YOUNG ADULT;

EID: 58149105923     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2008.01814.x     Document Type: Article

References (32)

1. Barnes PJ, Chung KF, Page CP. Inflammatory mediators and asthma. Pharmacol Rev 1988 40 : 49 84.
2. O'Hara KA, Kedda MA, Thompson PJ, Knight DA. Oncostatin M: an interleukin-6-like cytokine relevant to airway remodelling and the pathogenesis of asthma. Clin Exp Allergy 2003 33 : 1026 1032.
3. Knight DA, Ernst M, Anderson GP, Moodley YP, Mutsaers SE. The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression? Pharmacol Ther 2003 99 : 327 338.
4. Chu HW, Halliday JL, Martin RJ, Leung DY, Szefler SJ, Wenzel SE. Collagen deposition in large airways may not differentiate severe asthma from milder forms of the disease. Am J Respir Crit Care Med 1998 158 : 1936 1944.
5. Huang J, Olivenstein R, Taha R, Hamid Q, Ludwig MS. Enhanced proteoglycan deposition in the airway wall of atopic asthmatics. Am J Respir Crit Care Med 1999 160 : 725 729.
6. Jeffery PK. Remodeling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med 2001 164 : S28 S38.
7. Roche WR, Beasley R, Williams JH, Holgate ST. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1989 1 : 520 524.
8. Gizycki MJ, Adelroth E, Rogers AV, O'Byrne PM, Jeffery PK. Myofibroblast involvement in the allergen-induced late response in mild atopic asthma. Am J Respir Cell Mol Biol 1997 16 : 664 673.
9. Molet S, Hamid Q, Davoine F, Nutku E, Taha R, Page N et al. IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 2001 108 : 430 438.
10. Teran LM, Mochizuki M, Bartels J, Valencia EL, Nakajima T, Hirai K et al. Th1- and Th2-type cytokines regulate the expression and production of eotaxin and RANTES by human lung fibroblasts. Am J Respir Cell Mol Biol 1999 20 : 777 786.
11. Tschumperlin DJ, Drazen JM. Mechanical stimuli to airway remodeling. Am J Respir Crit Care Med 2001 164 : S90 S94.
12. Breen EC. Mechanical strain increases type I collagen expression in pulmonary fibroblasts in vitro. J Appl Physiol 2000 88 : 203 209.
13. Swartz MA, Tschumperlin DJ, Kamm RD, Drazen JM. Mechanical stress is communicated between different cell types to elicit matrix remodeling. Proc Natl Acad Sci USA 2001 98 : 6180 6185.
14. Ludwig MS, Ftouhi-Paquin N, Huang W, Page N, Chakir J, Hamid Q. Mechanical strain enhances proteoglycan message in fibroblasts from asthmatic subjects. Clin Exp Allergy 2004 34 : 926 930.
15. Le Bellego F, Plante S, Chakir J, Hamid Q, Ludwig MS. Differences in MAP kinase phosphorylation in response to mechanical strain in asthmatic fibroblasts. Respir Res 2006 7 : 68.
16. Vlahakis NE, Schroeder MA, Limper AH, Hubmayr RD. Stretch induces cytokine release by alveolar epithelial cells in vitro. Am J Physiol 1999 277 : L167 L173.
17. Jiang MJ, Yu YJ, Chen YL, Lee YM, Hung LS. Cyclic strain stimulates monocyte chemotactic protein-1 mRNA expression in smooth muscle cells. J Cell Biochem 1999 76 : 303 310.
18. Oudin S, Pugin J. Role of MAP kinase activation in interleukin-8 production by human BEAS-2B bronchial epithelial cells submitted to cyclic stretch. Am J Respir Cell Mol Biol 2002 27 : 107 114.
19. Kumar A, Knox AJ, Boriek AM. CCAAT/enhancer-binding protein and activator protein-1 transcription factors regulate the expression of interleukin-8 through the mitogen-activated protein kinase pathways in response to mechanical stretch of human airway smooth muscle cells. J Biol Chem 2003 278 : 18868 18876.
20. Dube J, Chakir J, Laviolette M, Saint MS, Boutet M, Desrochers C et al. In vitro procollagen synthesis and proliferative phenotype of bronchial fibroblasts from normal and asthmatic subjects. Lab Invest 1998 78 : 297 307.
21. Goulet F, Boulet LP, Chakir J, Tremblay N, Dube J, Laviolette M et al. Morphologic and functional properties of bronchial cells isolated from normal and asthmatic subjects. Am J Respir Cell Mol Biol 1996 15 : 312 318.
22. Laliberte R, Rouabhia M, Bosse M, Chakir J. Decreased capacity of asthmatic bronchial fibroblasts to degrade collagen. Matrix Biol 2001 19 : 743 753.
23. Kotaru C, Schoonover KJ, Trudeau JB, Huynh ML, Zhou X, Hu H et al. Regional fibroblast heterogeneity in the lung: implications for remodeling 2. Am J Respir Crit Care Med 2006 173 : 1208 1215.
24. Jafari B, Ouyang B, Li LF, Hales CA, Quinn DA. Intracellular glutathione in stretch-induced cytokine release from alveolar type-2 like cells 1. Respirology 2004 9 : 43 53.
25. Chiquet M, Sarasa-Renedo A, Tunc-Civelek V. Induction of tenascin-C by cyclic tensile strain versus growth factors: distinct contributions by Rho/ROCK and MAPK signaling pathways. Biochim Biophys Acta 2004 1693 : 193 204.
26. MacKenna DA, Dolfi F, Vuori K, Ruoslahti E. Extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts. J Clin Invest 1998 101 : 301 310.
27. Choe MM, Sporn PH, Swartz MA. Extracellular matrix remodeling by dynamic strain in a three-dimensional tissue-engineered human airway wall model. Am J Respir Cell Mol Biol 2006 35 : 306 313.
28. Pease JE, Sabroe I. The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy. Am J Respir Med 2002 1 : 19 25.
29. Kuhn C, III., Homer RJ, Zhu Z, Ward N, Flavell RA, Geba GP et al. Airway hyperresponsiveness and airway obstruction in transgenic mice. Morphologic correlates in mice overexpressing interleukin (IL-11 and IL-6 in the lung. Am J Respir Cell Mol Biol 2000 22 : 289 295.
30. Ammit AJ, Moir LM, Oliver BG, Hughes JM, Alkhouri H, Ge Q et al. Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle 1. Am J Physiol Lung Cell Mol Physiol 2007 292 : L199 L206.
31. Iozzo RV. Matrix proteoglycans: from molecular design to cellular function. Annu Rev Biochem 1998 67 : 609 652.
32. Bensadoun ES, Burke AK, Hogg JC, Roberts CR. Proteoglycan deposition in pulmonary fibrosis. Am J Respir Crit Care Med 1996 154 : 1819 1828.