Somatic mutation of pro-cell death Bif-1 gene is rare in common human cancers

APMIS

Volumn 116, Issue 10, 2008, Pages 939-940

  Kim, Min Sung ^a   Yoo, Nam Jin ^a   Lee, Sug Hyung ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Apoptosis; Bif 1; Cancer; Mutation

Indexed keywords

GENOMIC DNA;

BAX INTERACTING FACTOR 1 GENE; BREAST CARCINOMA; CANCER TISSUE; CELL DEATH; COLORECTAL CARCINOMA; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LETTER; LEUKEMIA; LIVER CELL CARCINOMA; LUNG CARCINOMA; MISSENSE MUTATION; ONCOGENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOMACH CARCINOMA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BREAST NEOPLASMS; CARCINOMA; CARCINOMA, LARGE CELL; COLORECTAL NEOPLASMS; HUMANS; LEUKEMIA, LYMPHOID; LUNG NEOPLASMS; MUTATION; NEOPLASMS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; STOMACH NEOPLASMS;

EID: 58149089453     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2008.01091.x     Document Type: Letter

References (5)

1. Takahashi Y, Karbowski M, Yamaguchi H, Kazi A, Wu Z, Sebti SM, et al. Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis. Mol Cell Biol 2005 25 : 9369 82.
2. Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, et al. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol 2007 9 : 1142 51.
3. Lee SH, Shin MS, Park WS, Kim SY, Kim HS, Han JY, et al. Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer. Oncogene 1999 18 : 3754 60.
4. Kim HS, Lee JW, Soung YH, Park WS, Kim SY, Lee JH, et al. Inactivating mutations of caspase-8 gene in colorectal carcinomas. Gastroenterology 2003 125 : 708 15.
5. Lee JW, Jeong EG, Soung YH, Nam SW, Lee JY, Yoo NJ, et al. Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas. Pathology 2006 38 : 312 5.