Oxidative stress in children on hemodialysis: Value of autoantibodies against oxidized low-density lipoprotein

Pediatric Nephrology

Volumn 24, Issue 2, 2009, Pages 387-393

  Cengiz, Nurcan ^a   Baskin, Esra ^a   Sezgin, Nurzen ^a   Agras, Pinar ^a   Haberal, Mehmet ^a  

^a BASKENT UNIVERSITY   (Turkey)

Author keywords

Cardiovascular disease; Children; Hemodialysis; Inflammation; Oxidative stress

Indexed keywords

ALBUMIN; APOLIPOPROTEIN A1; AUTOANTIBODY; C REACTIVE PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROPOIETIN; FERRITIN; HIGH DENSITY LIPOPROTEIN; IRON; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; PREALBUMIN; TRANSFERRIN;

ADOLESCENT; ANEMIA; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHRONIC DISEASE; CHRONIC KIDNEY FAILURE; CLINICAL ARTICLE; CONTROLLED STUDY; DYSLIPIDEMIA; FEMALE; HEMATOCRIT; HEMODIALYSIS; HUMAN; HYPERTENSION; INFLAMMATION; LABORATORY TEST; LIPID ANALYSIS; MALE; MALNUTRITION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DETERMINATION; RISK ASSESSMENT; RISK FACTOR;

ADOLESCENT; AUTOANTIBODIES; CHILD; FEMALE; HUMANS; INFLAMMATION; KIDNEY FAILURE, CHRONIC; LIPOPROTEINS, LDL; MALE; OXIDATIVE STRESS; PREDICTIVE VALUE OF TESTS; RENAL DIALYSIS; RISK FACTORS;

EID: 58149088190     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-008-1004-x     Document Type: Article

References (54)

1. Gruppen MP, Groothoff JW, Prins M (2003) Cardiac disease in young adult patients with end-stage renal disease since childhood: A Dutch cohort study. Kidney Int 63:1058-1065
2. Parekh RS, Carroll CE, Wolfe RA (2000) Cardiovascular mortality in children and young adults with end-stage kidney disease. J Pediatr 141:191-197
3. Mitsnefes MM (2002) Pediatric end-stage renal disease: Heart as a target. J Pediatr 141:162-164
4. Scharer K, Schmidt KG, Soergel M (1999) Cardiac function and structure in patients with chronic renal failure. Pediatr Nephrol 13:951-965
5. Mitsnefes MM (2008) Cardiovascular complications of pediatric chronic kidney disease. Pediatr Nephrol 23:27-39
6. Stenvinkel P, Heimburger O, Paulture F (1999) Strong association between malnutrition, inflammation and atherosclerosis in chronic renal failure. Kidney Int 55:1899-1911
7. Stenvinkel P (2003) Interactions between inflammation, oxidative stress and endothelial dysfunction in end-stage renal disease. J Ren Nutr 13:144-148
8. Oberg BP, McMenamin E, Lucas FL (2004) Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. Kidney Int 65:1009-1016
9. Spittle MA, Hoenich NA, Handelman GJ (2001) Oxidative stress and inflammation in hemodialysis patients. Am J Kidney Dis 38:1408-1413
10. Dasgupta A, Hussain S, Ahmad S (1992) Increased lipid peroxidation in patients on maintenance hemodialysis. Nephron 60:56-59
11. Toborek M, Wasik T, Drozdz M (1992) Effect of hemodialysis on lipid peroxidation and antioxidant system in patients with chronic renal failure. Metabolism 41:1229-1232
12. Nguyen-Khoa T, Massy ZA, De Bandt JP (2001) Oxidative stress and hemodialysis: Role of inflammation and duration of dialysis treatment. Nephrol Dial Transplant 16:335-340
13. Panichi V, Migliori M, De Pietro S (2000) The link of biocompatibility to cytokine production. Kidney Int 58:96-103
14. Kaysen GA, Eiserich JP (2003) Characteristics and effects of inflammation in end-stage renal disease. Semin Dial 16:438-446
15. Maroti Z, Nemeth I, Turi S (2004) Heme oxygenase 1 expression in young uremic patients on hemodialysis. Pediatr Nephrol 19:426-431
16. Ece A, Gurkan F, Kervancioglu M, Kocamaz H, Gunes A, Atamer Y, Selek S (2006) Oxidative stress, inflammation and early cardiovascular damage in children with chronic renal failure. Pediatr Nephrol 21:545-552
17. Berliner JA, Navab M, Fogelman AM (1995) Atherosclerosis: Basic mechanisms and oxidation, inflammation and genetics. Circulation 91:2488-2496
18. Ross R (1993) The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 362:801-809
19. Steinbrecher UP, Zhang HF, Lougheed M (1990) Role of oxidatively modified LDL in atherosclerosis. Free Radic Biol Med 9:155-168
20. Steinberg D, Parathasarathy S, Carew TE (1989) Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 320:915-924
21. Witztum JL (1993) Role of oxidized low-density lipoprotein in atherogenesis. Br Heart J 69:12-13
22. Brown MS, Goldstein J (1983) Lipoprotein metabolism in the macrophage. Ann Rev Biochem 52:223-261
23. Yl-Herttuala S, Palinski W, Rosenfeld ME, Parthasarathy S, Carew TE, Butler S, Witztum JL, Steinberg D (1989) Evidence for the presence of oxidatively modified LDL in atherosclerotic lesions of rabbit and man. J Clin Invest 284:1086-1095
24. Maggi E, Bellazzi R, Falaschi F (1994) Enhanced LDL oxidation in uremic patients: An additional mechanism for accelerated atherosclerosis? Kidney Int 45:876-883
25. Loughrey CM, Young IS, Lighbody JH (1994) Oxidative stress in hemodialysis. Q J Med 87:679-683
26. Nemeth I, Turi S, Haszon I (2000) Vitamin E alleviates the oxidative stress of erythropoietin in uremic children on hemodialysis. Pediatr Nephrol 14:13-17
27. Shoji T, Nishizawa Y, Fukumoto M (2000) Inverse relationship between circulating oxidized low density lipoprotein and anti-oxLDL antibody levels in healthy subjects. Atherosclerosis 148:171-177
28. Fukumoto M, Shoji T, Emoto M (2000) Antibodies against oxidized LDL and carotid intima media thickness in a healthy population. Atheroscler Thromb Vasc Biol 20:703-707
29. American Academy of Pediatrics, National Cholesterol Education Program (1992) Report of the expert panel on blood cholesterol levels in children and adolescents. Pediatrics 89:525-564
30. Tinahones FJ, Gomez-Zumaquero JM, Garrido-Sanchez L, Garcia-Fuentes E, Rojo-Martinez G, Esteva I, Adana MS, Cardona F, Soriguer F (2005) Influence of age and sex on levels of anti-oxidized LDL antibodies and anti-LDL immune complexes in the general population. J Lipid Res 46:452-457
31. Salonen JT, Yla Herttula S, Yamamoto R, Butler S, Korpela H, Salonen R, Nyyssönen K, Palinski W, Witztum JL (1992) Autoantibodies against oxidized LDL and progression of carotid atherosclerosis. Lancet 339:883-887
32. Maggi E, Bellazzi R, Gazo A (1994) Autoantibodies against oxidatively modified LDL in uremic patients undergoing dialysis. Kidney Int 46:869-876
33. Bergesio F, Monzani G, Ciuti R (2001) Autoantibodies against oxidized LDL in chronic renal failure: Role of renal function, diet and lipids. Nephron 87:127-133
34. Palinsky W, Miller E, Witztum JL (1995) Immunization of low-density lipoprotein receptor deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis. Proc Natl Acad Sci U S A 92:821-825
35. Rosealar SE, Schonfeld G, Daugherty A (1995) Enhanced development of atherosclerosis in cholesterol-fed rabbits by suppression of cell-mediated immunity. J Clin Invest 96:1389-1394
36. Horkko S, Binder JC, Shaw PX (2000) Immunological responses to oxidized LDL. Free Radic Biol Med 28:1771-1779
37. Khoschsorur G, Tatzber F, Freigassner M (1996) Inverse correlation of MDA and anti-oxLDL IgG antibodies in transplantation patients. Med Sci Res 24:851-856
38. Shoji T, Fukumoto M, Emoto M (2002) Antibody to oxidized low-density lipoprotein and cardiovascular mortality in end-stage renal disease. Kidney Int 62:2230-2237
39. Shoji T, Kimoto E, Shinohara K (2003) The association of antibodies against low-density lipoprotein with atherosclerosis in hemodialysis patients. Kidney Int 84:128-130
40. Festa A, Kopp H, Schernthaner G (1998) Autoantibodies to oxidized low-density lipoproteins in IDDM are inversely related to metabolic control and microvascular complications. Diabetologia 41:350-356
41. Panichi V, Migliori M, De Pietro S (2001) C reactive protein in patients with chronic renal failure. Ren Fail 23:551-562
42. Besbas N, Ozdemir S, Saatci U (1998) Nutritional assessment of children on hemodialysis: Value of IGF-I, TNF-alpha and IL-Ibeta. Nephrol Dial Transplant 13:1484-1488
43. Ekim M, Ikinciogullari A, Ulukol B (2003) Evaluation of nutritional status and factors related to malnutrition in children on CAPD. Perit Dial Int 23:557-562
44. Kaysen G, Rathore V, Shearer GC (1995) Mechanisms of hypoalbuminemia in hemodialysis patients. Kidney Int 48:510-516
45. Sezer S, Ozdemir FN, Arat Z (2002) Triad of malnutrition, inflammation, and atherosclerosis in hemodialysis patients. Nephron 91:456-462
46. Kaysen GA, Dublin JA, Müller HG (2000) The acute phase response varies with time and predicts serum albumin levels in hemodialysis patients. Kidney Int 58:346-352
47. Berenson GS, Srinivasan SR, Bao W, Newman WP 3rd (1998) Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med 338:1650-1656
48. Goodman WG, Goldin J, Kuizon BD (2000) Coronary artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med 342:1478-1483
49. Querfeld U (2002) Is atherosclerosis accelerated in young patients with end-stage renal disease? The contribution of paediatric nephrology. Nephrol Dial Transplant 17:719-722
50. Samuelson O, Attman PO, Knight-Gibson C (1994) Lipoprotein abnormalities without hyperlipidemia in moderate renal insufficiency. Nephrol Dial Transplant 9:1580-1585
51. Attman PO, Alaupovic P, Tavella M (1996) Abnormal lipid and apolipoprotein composition of major lipoprotein density classes in patients with chronic renal failure. Nephrol Dial Transplant 11:63-69
52. Zacchello G, Pagnan A, Sidran MP (1987) Further definition of lipid-lipoprotein abnormalities in children with various degrees of chronic renal insufficiency. Pediatr Res 21:462-465
53. Turi S, Nemeth I, Vargha I (1991) Erythrocyte defense mechanisms against free oxygen radicals in haemodialysed uraemic children. Pediatr Nephrol 5:179-183
54. Gunnel J, Yeun JY, Depner TA (1999) Acute-phase response predicts erythropoietin resistance in hemodialysis and peritoneal dialysis patients. Am J Kidney Dis 33:63-72