Embryo biopsy: The fate of abnormal pronuclear embryos

Reproductive BioMedicine Online

Volumn 17, Issue 6, 2008, Pages 782-788

  Noyes, Nicole ^a   Fino, M Elizabeth ^a   Krey, Lewis ^a   McCaffrey, Caroline ^a   Adler, Alexis ^a   Grifo, James ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chromosomes; Embryo biopsy; Embryo morphology; Fertilization; Preimplantation genetic screening; Pronuclear

Indexed keywords

ADULT; ANEUPLOIDY; ARTICLE; BIOPSY TECHNIQUE; BLASTOCYST; CHROMOSOME ANALYSIS; CONTROLLED STUDY; EMBRYO; EMBRYO BIOPSY; EMBRYO TRANSFER; FEMALE; FERTILIZATION; GENETIC SCREENING; HUMAN; HUMAN TISSUE; KARYOTYPE; MEIOSIS; MORPHOLOGY; NIDATION; PREIMPLANTATION EMBRYO; PRONUCLEUS; Y CHROMOSOME; ZYGOTE;

EID: 58149087567     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-6483(10)60405-1     Document Type: Article

References (35)

1. Abbott AL, Ducibella T 2001 Calcium and the control of mammalian cortical granule exocytosis. Frontiers in Bioscience 6, D792-D806.
2. Bahçe M, Cohen J, Munné S 1999 Preimplantation genetic diagnosis of aneuploidy: were we looking at the wrong chromosomes? Journal of Assisted Reproduction and Genetics 16, 176-181.
3. Balaban B, Kayban Y, Bulent U et al. 2004 Pronuclear morphology predicts embryo development and chromosome constitution. Reproductive BioMedicine Online 8, 695-700.
4. Balakier H, MacLusky N, Casper R 1993 Characterization of the first cell cycle in human zygotes implications for cryopreservation. Fertility and Sterility 59, 359-365.
5. Bleil JD, Wassarman PM 1981 Mammalian sperm-egg interaction: Fertilization of mouse eggs triggers modifications of the major zona pellucida glycoprotein, ZP2. Developmental Biology 86, 189-197.
6. Capmany G, Taylor A, Braude P et al. 1996 Cell cycle regulations: The timing of pronuclear formation, DNA synthesis and cleavage in the human 1-cell embryo. Molecular Human Reproduction 2, 299-306.
7. Collas P, Poccia D 1998 Remodeling the sperm nucleus into a male pronucleus at fertilization. Theriogenology 43, 129-140.
8. Evans JP, Florman HM 2002 The state of the union: the cell biology of fertilization. Nature Cell Biology 4, S57-S63.
9. Feenan K, Herbert M 2006 Can 'abnormally' fertilized zygotes give rise to viable embryos? Human Fertility (Cambridge) 9, 157-169.
10. Flaherty SP, Payne D, Swann NJ et al. 1995 Aetiology of failed and abnormal fertilization after intracytoplasmic sperm injection. Human Reproduction 10, 2623-2629.
11. Grifo JA 1992 Preconception and preimplantation genetic diagnosis: Polar body, blastomere, and trophectoderm biopsy. In: Cohen J, Malter HE, Talansky BE, Grifo J (eds) Micromanipulation of Gametes and Embryos. Raven Press, New York, pp. 223-249.
12. Kaufman M 1983 Early Mammalian Development: Parthenogenetic Studies. Cambridge University Press, Cambridge, UK.
13. Keefe D, Liu L, Wang W et al. 2003 Imaging meiotic spindles by polarization light microscopy: principles and applications to IVF. Reproductive BioMedicine Online 7, 24-29.
14. Konc J, Kanyó K, Cseh S 2004 Visualization and examination of the meiotic spindle in human oocytes with PolScope. Journal of Assisted Reproduction and Genetics 21, 349-353.
15. Levron J, Munné S, Willadsen S et al. 1995 Male and female genomes associated in a single pronucleus in human zygotes. Biology of Reproduction 52, 653-657.
16. Manor D, Kol S, Lewit N et al. 1996 Undocumented embryos: do not trash them, FISH them. Human Reproduction 11, 2502-2506.
17. Marieb E 2001 Human Anatomy and Physiology 5th edn. Benjamin Cummings, San Francisco, pp. 1119-1122.
18. Moore K, Persaud TVN 2003 The Developing Human: Clinically Oriented Embryology 7th edn. Saunders, Philadelphia.
19. Munné S, Cohen J 1998 Chromosome abnormalities in human embryos. Human Reproduction Update 4, 842-855.
20. Munné S, Weier U 1996 Simultaneous enumeration of chromosomes 13, 18, 21, X and Y in interphase cells for preimplantation genetic diagnosis of aneuploidy. Cytogenetics and Cell Genetics 75, 263-270.
21. Munné S, Tang Y, Grifo J et al. 1993 Origin of single pronucleated zygotes. Journal of Assisted Reproduction and Genetics 10, 276-279.
22. Munné S, Magli C, Bahçe M et al. 1998 Preimplantation diagnosis of the aneuploidies most commonly found in spontaneous abortions and live births: XY, 13, 14, 15, 16, 18, 21, 22. Prenatal Diagnosis 18, 1459-1466.
23. Nagy Z, Janssenswillen C, Janssens R et al. 1998 Timing of oocyte activation, pronucleus formation and cleavage in humans after intracytoplasmic sperm injection (ICSI) with testicular spermatozoa and after ICSI or in-vitro fertilization on sibling oocytes with ejaculated spermatozoa. Human Reproduction 13, 1606-1612.
24. Payne D, Flaherty S, Barry M et al. 1997 Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography. Human Reproduction 12, 532-541.
25. Plachot M 1991 Chromosome analysis of oocytes and embryos. In: Verlinsky Y, Kuliev A (eds) Preimplantation Genetics Plenum Press, New York, pp. 103-112.
26. Rienzi L, Ubaldi F, Iacobelli M et al. 2005 Significance of morphological attributes of the early embryo. Reproductive BioMedicine Online 10, 669-681.
27. Sathananthan A, Ratnam S, Ng S et al. 1996 The sperm centriole: its inheritance, replication and perpetuation in early human embryos. Human Reproduction 11, 345-356.
28. Simerly C, Wu GJ, Zoran S et al., 1995 The paternal inheritance of the centrosome, the cell's microtubule-organizing center, in humans, and the implications for infertility. Nature Medicine 1, 47-52.
29. Staessen C, Van Steirteghem A 1997 The chromosomal constitution of embryos developing from abnormally fertilized oocytes after intracytoplasmic sperm injection and conventional in-vitro fertilization. Human Reproduction 12, 321-327.
30. Staessen C, Janssenwillen C, Devroey P et al. 1993 Cytogenetic and morphological observations of single pronucleated human oocytes after in-vitro fertilization. Human Reproduction 8, 221-223.
31. Sultan K, Munné S, Palermo G et al. 1995 Chromosomal status of uni-pronuclear human zygotes following IVF and intracytoplasmic sperm injection. Human Reproduction 10, 132-136.
32. Tesarik J, Greco E 1999 The probability of abnormal preimplantation development can be predicted by a single static observation on pronuclear stage morphology. Human Reproduction 14, 1318-1323.
33. Tesarik J, Mendoza C 1996 Spermatid injection into human oocytes. I. Laboratory techniques and s ecial features of zygote development. Human Reproduction 11, 772-779.
34. Williams CJ 2002 Signalling mechanisms of mammalian oocyte activation. Human Reproduction Update 8, 313-321.
35. Xu Y, Zhang J, Grifo J et al. 2005 DNA methylation patterns in human tripronucleate zygotes. Molecular Human Reproduction 11, 167-171.