Role of early-life environmental influences in the development of asthma. How painful is it when you catch a bad cold too early?

Journal of Asthma

Volumn 45, Issue SUPPL. 1, 2008, Pages 25-28

  Piedimonte, Giovanni ^a,b   Perez, Miriam K ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Asthma; Leukotrienes; Mast cell; Neurogenic inflammation; Neurotrophin; Respiratory syncytial virus; Substance P

Indexed keywords

LEUKOTRIENE DERIVATIVE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN;

ASTHMA; COMMON COLD; ENVIRONMENTAL FACTOR; HUMAN; IMMUNE RESPONSE; MAST CELL; NEUROPATHIC PAIN; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVIEW; VIRUS INFECTION;

ASTHMA; ENVIRONMENT; HUMANS; HYGIENE HYPOTHESIS; MAST CELLS; NEUROIMMUNOMODULATION; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS;

EID: 58149086372     PISSN: 02770903     EISSN: 15324303     Source Type: Journal    
DOI: 10.1080/02770900802569991     Document Type: Review

References (23)

1. Piedimonte G, Simoes EA. Respiratory syncytial virus and subsequent asthma: one step closer to unravelling the gordian knot? Eur Respir J 2002; 20:515-517.
2. Piedimonte G. The association between respiratory syncytial virus infection and reactive airway disease. Resp Med 2002; 96(suppl. B):S26-S30.
3. Stein RT, Sherril D, Morgan WJ, Holberg CJ, Halonen M, Taussig LM, et al. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 1999; 354:541-545.
4. Sigurs N, Bjarnason R, Sigurbergsson F, Kjellman B. Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Cell Mol Biol 2000; 161:1501-1507.
5. Lemanske JR. Immunologic mechanisms in RSV-related allergy and aAsthma. In P.W. Hiatt (ed.). RSV and Asthma: Is There a Link? New York: American Thoracic Society, 1998, 11-16.
6. Larsen GL, Colasurdo GN. Neural control mechanisms within airways: disruption by respiratory syncytial virus. J Pediatr 1999; 135:S21-S27.
7. Piedimonte G. Neural mechanisms of respiratory syncytial virus-induced inflammation and prevention of respiratory syncytial virus sequelae. Am J Respir Crit Care Med 2001; 163:S18-S21.
8. Piedimonte G. Tachykinin peptides, receptors, and peptidases in airway disease. Exp Lung Res 1995; 21:809-834.
9. Piedimonte G, Rodriguez MM, King KA, Mclean S, Jiang X. Respiratory syncytial virus upregulates expression of the substance P receptor in rat lungs. Am J Physiol Lung Cell Mol Physiol 1999; 277:L831-L840.
10. King KA, Hu C, Rodriguez MM, Romaguera R, Jiang X, Piedimonte G. Exaggerated neurogenic inflammation and substance P receptor upregulation in RSV-infected weanling rats. Am J Respir Cell Mol Biol 2001; 24:101-107.
11. Auais A, Adkins B, Napchan G, Piedimonte G. Immunomodulatory effects of sensory nerves during respiratory syncytial virus infection in rats. Am J Physiol Lung Cell Mol Physiol 2003; 285:L105-L113.
12. Wedde-Beer K, Hu C, Rodriguez MM, Piedimonte G. Leukotrienes mediate neurogenic inflammation in lungs of young rats infected with respiratory syncytial virus. Am J Physiol Lung Cell Mol Physiol 2002; 282:L1143-L1150.
13. Bauer O, Razin E. Mast cell-nerve interactions. News Physiol Sci 2000; 15:213-218.
14. Van Schaik SM, TristramDA, Nagpal IS, Hintz KM,Welliver RCI,Welliver RC. Increased production of IFN-gamma and cysteinyl leukotrienes in virus-induced wheezing. J Allergy Clin Immunol 1999; 103:630-636.
15. Volovitz B, Welliver RC, De Castro G, Krystofik D, Ogra PL. The release of leukotrienes in the respiratory tract during infection with respiratory syncytial virus: role in obstructive airway disease. Pediatr Res 1988; 24:504-507.
16. Levi-Montalcini R. The nerve growth factor 35 years later. Science 1987; 237:1154-1162.
17. Hu C, Wedde-Beer K, Auais A, Rodriguez MM, Piedimonte G. Nerve growth factor and nerve growth factor receptors in respiratory syncytial virus-infected lungs. Am J Physiol Lung Cell Mol Physiol 2002; 283:L494-L502.
18. Kernie SG, Parada LF. The molecular basis for understanding neurotrophins and their relevance to neurologic disease. Arch Neurol 2000; 57:654-657.
19. Renz H. Neurotrophins in bronchial asthma. Respir Res 2001; 2:265-268.
20. Leon A, Buriani A, Dal Toso R, Fabris M, Romanello S, Aloe L, et al. Mast cells synthesize, store, and release nerve growth factor. Proc Nat Acad Sci USA 1994; 91:3739-3743.
21. Nilsson G, Forsberg-Nilsson K, Xiang Z, Hallbook F, Nilsson K, Metcalfe D. Human mast cells express functional trkA and are a source of nerve growth factor. Eur J Immunol 1997; 27:2295-2301.
22. Ehrhard P, Erb P, Graumann U, Otten U. Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase trk in activated CD4-positive T-cell clones. Proc Nat Acad Sci USA 1993; 90:10984-10988.
23. Braun A, Lommatzsch M, Lewin GR, Virchow JC, Renz H. Neurotrophins: a link between airway inflammation and airway smooth muscle contractility in asthma. Int Arch Allergy Immunol 1999; 118:163-165.