Intranodular blood supply correlates well with biological malignancy grade determined by tumor growth rate in pathologically proven hepatocellular carcinoma

Oncology

Volumn 75, Issue SUPPL. 1, 2008, Pages 55-64

  Kudo, Masatoshi ^a   Tochio, Hitoshi ^b  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KOBE CITY MEDICAL CENTER GENERAL HOSPITAL   (Japan)

Author keywords

Computed tomography during arterial portography; Intranodular blood supply; Malignancy grade; Multistep hepatocarcinogenesis; Tumor volume doubling time; Ultrasound angiography

Indexed keywords

BIOLOGICAL MARKER; CARBON DIOXIDE;

ADULT; AGED; ANGIOGRAPHY; CANCER GRADING; CELL DIFFERENTIATION; COMPUTER ASSISTED TOMOGRAPHY; CONFERENCE PAPER; CONTROLLED STUDY; ECHOGRAPHY; FOLLOW UP; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MICROBUBBLE; PORTAL PHLEBOGRAPHY; PORTAL VEIN BLOOD; PORTAL VEIN BLOOD FLOW; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR VOLUME; ULTRASOUND; VASCULARIZATION;

AGED; ANGIOGRAPHY; BLOOD FLOW VELOCITY; CARBON DIOXIDE; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CONTRAST MEDIA; HUMANS; LIVER; LIVER CIRCULATION; LIVER NEOPLASMS; MICROBUBBLES; MIDDLE AGED; TOMOGRAPHY, X-RAY COMPUTED; ULTRASONOGRAPHY;

EID: 58149085349     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000173425     Document Type: Conference Paper

References (15)

1. Kudo M, Tomita S, Tochio H, Kashida H, Hirasa M, Todo A: Hepatic focal nodular hyperplasia: specific findings at dynamic contrast-enhanced US with carbon dioxide microbubbles. Radiology 1991;179:377-382.
2. Kudo M, Tomita S, Tochio H, Mimura J, Okabe Y, Kashida H, Hirasa M, Ibuki Y, Todo A: Sonography with intraarterial infusion of carbon dioxide microbubbles (sonographic angiography): value in differential diagnosis of hepatic tumors. AJR Am J Roentgenol 1992;158:65-74.
3. 2 microbubbles. Radiology 1992;182:155-160.
4. Matsui O, Kadoya M, Kameyama T, Yoshikawa J, Takashima T, Nakanuma Y, Unoura M, Kobayashi K, Izumi R, Ida M, et al: Benign and malignant nodules in cirrhotic livers: distinction based on blood supply. Radiology 1991;178:493-497.
5. Majima Y: Growth rate of heptocellular carcinoma by ultrasonography and its clinical significance (in Japanese). Acta Hepatol Jpn 1984;25:754-765.
6. Kudo M, Okanoue T; Japan Society of Hepatology: Management of hepatocellular carcinoma in Japan: consensus-based clinical practice manual proposed by the Japan Society of Hepatology. Oncology 2007;72(suppl 1):2-15.
7. Tochio H, Tomita S, Kudo M, Mimura J, Hamada M, Minowa K, Kashida H, Okabe Y, Hirasa M, Ibuki Y, Komori H, Orino A, Todo A: Growth speed of hepatocellular carcinoma - relationship with arterial vascularity evaluated by US angiography (in Japanese). Acta Hepatol Jpn (Jpn J Hepatology) 1992;33:758-765.
8. Tochio H, Tomita S, Kudo M, Okabe Y, Kashida H, Hamada M, Yamamoto K, Terai Y, Itani T, Mimura J, Hirasa M, Ibuki Y, Komori H, Orino A, Todo A: Clinical tracing of small hypovacular hepatic nodules associated with chronic liver disease (in Japanese). Acta Hepatol Jpn (Jpn J Hepatology) 1994;35:333-346.
9. Tochio H, Tomita S, Kudo M, Hirasa M, Kashida H, Okabe Y, Mimura J, Onoue K, Minowa K, Hamada M, Shimada K, Morimoto Y, Ibuki Y, Komori H, Orino A, Todo A: Hypovascular hepatocellular carcinomas and hepatic borderline lesions on ultrasound angiography - relationship between tumor growth speed and portal perfusion (in Japanese). J Med Ultrasonics 1991;18:742-748.
10. Fukunaga T, Kudo M, Tochio H, Okabe Y, Orino A: Natural course of small nodular lesions with intranodular preserved portal supply in cirrhotic liver. Oncology 2007;72(suppl 1):24-29.
11. Kudo M: Imaging diagnosis of hepatocellular carcinoma and premalignant/borderline lesions. Semin Liver Dis 1999;19:297-309.
12. Kudo M: Multistep human hepatocarcinogenesis: correlation of imaging with pathology. J Gastroenterol 2008, in press.
13. Kudo M: Early detection and characterization of hepatocellular carcinoma: value of imaging multistep human hepatocarcinogenesis. Intervirology 2006;49:64-69.
14. Kudo M: Atypical large well-differentiated hepatocellular carcinoma with benign nature: a new clinical entity. Intervirology 2004;47:227-237.
15. Zheng RQ, Zhou P, Kudo M: Hepatocellular carcinoma with nodule-in-nodule appearance: demonstration by contrast-enhanced coded phase inversion harmonic imaging. Intervirology 2004;47:184-190.