A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection

Journal of Viral Hepatitis

Volumn 16, Issue 1, 2009, Pages 45-52

  Zhou, J ^a,c   Smith, D K ^a   Lu, L ^a   Poon, V K M ^a   Ng, F ^a   Chen, D Q ^a   Huang, J D ^a   Yuen, K Y ^a   Cao, K Y ^a,b   Zheng, B J ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b SUN YAT SEN UNIVERSITY   (China)

^c NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION   (United States)

Author keywords

HBV infection; IFNAR1; Protein stability; SNP

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; ALPHA BETA INTERFERON RECEPTOR 1; UNCLASSIFIED DRUG;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CHRONIC HEPATITIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; FLOW CYTOMETRY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HEPATITIS B; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN STABILITY; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

AMINO ACID SUBSTITUTION; DISEASE SUSCEPTIBILITY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HEPATITIS B, CHRONIC; HUMANS; MALE; MUTATION, MISSENSE; POINT MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, INTERFERON ALPHA-BETA; SEQUENCE ANALYSIS, DNA;

EID: 58149083528     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2008.01040.x     Document Type: Article

References (21)

1. Lin TM, Chen CJ, Wu MM et al. Hepatitis B virus markers in Chinese twins. Anticancer Res 1989 9 (3 737 741.
2. Thio CL, Thomas DL, Karacki P et al. Comprehensive analysis of class I and class II HLA antigens and chronic hepatitis B virus infection. J Virol 2003 77 (22 12083 12087.
3. Hohler T, Kruger A, Gerken G, Schneider PM, Meyer zum Buschenefelde KH, Rittner C. A tumor necrosis factor-alpha (TNF-alpha) promoter polymorphism is associated with chronic hepatitis B infection. Clin Exp Immunol 1998 111 (3 579 582.
4. Kim YJ, Lee HS, Yoon JH et al. Association of TNF-alpha promoter polymorphisms with the clearance of hepatitis B virus infection. Hum Mol Genet 2003 12 (19 2541 2546.
5. Thio CL, Mosbruger T, Astemborski J et al. Mannose binding lectin genotypes influence recovery from hepatitis B virus infection. J Virol 2005 79 (14 9192 9196.
6. Atabani SF, Thio CL, Divanovic S et al. Association of CTLA4 polymorphism with regulatory T cell frequency. Eur J Immunol 2005 35 (7 2157 2162.
7. Frodsham AJ, Zhang L, Dumpis U et al. Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence. Proc Natl Acad Sci USA 2006 103 (24 9148 9153.
8. Chisari FV, Ferrari C. Hepatitis B virus immunopathogenesis. Annu Rev Immunol 1995 13 : 29 60.
9. Guidotti LG, Chisari FV. Noncytolytic control of viral infections by the innate and adaptive immune response. Annu Rev Immunol 2001 19 : 65 91.
10. Pestka S, Krause CD, Walter MR. Interferons, interferon-like cytokines, and their receptors. Immunol Rev 2004 202 : 8 32.
11. Brierley MM, Fish EN. Review: IFN-alpha/beta receptor interactions to biologic outcomes: understanding the circuitry. J Interferon Cytokine Res 2002 22 (8 835 845.
12. Zhou J, Lu L, Yuen MF et al. Polymorphisms of type I interferon receptor 1 promoter and their effects on chronic hepatitis B virus infection. J Hepatol 2007 46 (2 198 205.
13. Zheng B, Graham FL, Johnson DC, Hanke T, McDermott MR, Prevec L. Immunogenicity in mice of tandem repeats of an epitope from herpes simplex gD protein when expressed by recombinant adenovirus vectors. Vaccine 1993 11 (12 1191 1198.
14. Zheng BJ, Graham FL, Prevec L. Transcription units of E1a, E1b and pIX regions of bovine adenovirus type 3. J Gen Virol 1999 7 : 1735 1742.
15. Cheng J, Randall A, Baldi P. Prediction of protein stability changes for single-site mutations using support vector machines. Proteins 2006 62 (4 1125 1132.
16. Pogue SL, Preston BT, Stalder J, Bebbington CR, Cardarelli PM. The receptor for type I IFNs is highly expressed on peripheral blood B cells and monocytes and mediates a distinct profile of differentiation and activation of these cells. J Interferon Cytokine Res 2004 24 (2 131 139.
17. Domanski P, Colamonici OR. The type-I interferon receptor. The long and short of it. Cytokine Growth Factor Rev 1996 7 (2 143 151.
18. Mogensen KE, Lewerenz M, Reboul J, Lutfalla G, Uze G. The type I interferon receptor: structure, function, and evolution of a family business. J Interferon Cytokine Res 1999 19 (10 1069 1098.
19. Lu J, Chuntharapai A, Beck J et al. Structure-function study of the extracellular domain of the human IFN-alpha receptor (hIFNAR1) using blocking monoclonal antibodies: the role of domains 1 and 2. J Immunol 1998 160 (4 1782 1788.
20. Cutrone EC, Langer JA. Identification of critical residues in bovine IFNAR-1 responsible for interferon binding. J biol chem 2001 276 (20 17140 17148.
21. Clackson T, Wells JA. A hot spot of binding energy in a hormone-receptor interface. Science 1995 267 (5196 383 386.