Dimeric proanthocyanidins from the roots of Ephedra sinica

Planta Medica

Volumn 74, Issue 15, 2008, Pages 1823-1825

  Tao, Huaming ^a,b   Wang, Lishu ^c,d   Cui, Zhanchen ^a   Zhao, Daqing ^c   Liu, Yonghong ^b  

^a JILIN UNIVERSITY   (China)

^b SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY   (China)

^c CHANGCHUN UNIVERSITY OF CHINESE MEDICINE   (China)

^d Jilin Provincial Academy of Chinese Medicine Sciences   (China)

Author keywords

Cytotoxicity; Ephedra sinica Stapf; Ephedraceae; Ephedrannin B; Mahuannin E; Proanthocyanidins

Indexed keywords

5,7,4' TRIHYDROXYFLAVAN EPIAFZELECHIN; 5,7,4' TRIHYDROXYFLAVAN KAEMPFEROL; ANTINEOPLASTIC AGENT; DIMER; EPHEDRA SINICA EXTRACT; EPHEDRANNIN A; EPHEDRANNIN B; MAHUANNIN D; MAHUANNIN E; PROANTHOCYANIDIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; EPHEDRA SINICA; HELA CELL; HUMAN; HUMAN CELL; IC 50; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; STRUCTURE ANALYSIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CYTOTOXINS; DRUG SCREENING ASSAYS, ANTITUMOR; EPHEDRA SINICA; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PLANT EXTRACTS; PLANT ROOTS; PROANTHOCYANIDINS;

EPHEDRA SINICA; EPHEDRACEAE;

EID: 58049216303     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1088321     Document Type: Article

References (14)

1. Ding L, Shi S, Cui J, Wang S, Wang Z. Advances in research of chemical constituents and pharmacological activities of Ephedra. Zhong Guo Zhong Yao Za Zhi 2006; 31: 1661-4
2. Hikino H, Takahashi M, Konno C. Structure of ephedrannin A, a hypotensive principle of Ephedra roots. Tetrahedron Lett 1982; 23: 673-6
3. Tamada M, Endo K, Hikino H, Kabuto C. Structure of ephedradine A, a hypotensive principle of Ephedra roots. Tetrahedron Lett; 1979: 873-6
4. Tamada M, Endo K, Hikino H. Structure of ephedradine B, a hypotensive principle of Ephedra roots. Heterocycles 1979; 12: 783-9
5. Konno C, Tamada M, Endo K, Hikino H. Structure of ephedradine C, a hypotensive principle of Ephedra roots. Heterocycles 1980; 14: 295-8
6. Hikino H, Ogata M, Konno C. Structure of ephedradine D, a hypotensive principle of Ephedra roots. Heterocycles 1982; 17: 155-8
7. Hikino H, Ogata K, Konno C, Sato S. Hypotensive actions of ephedradines, macrocyclic spermine alkaloids of Ephedra roots. Planta Med 1983; 48: 290-3
8. Hikino H, Ogata M, Konno C. Structure of feruloylhistamine, a hypotensive principle of Ephedra roots. Planta Med 1983; 48: 108-10
9. Hikino H, Koso Y, Ogata M, Konno C, Aisaka K, Kubota H et al. Pharmacological actions of analogues of feruloylhistamine, an imidazole alkaloid of Ephedra roots. Planta Med 1984; 50: 478-80
10. Tamada M, Endo K, Hikino H. Maokonine, hypertensive principle of Ephedra roots. Planta Med 1978; 34: 291-3
11. Hikino H, Shimoyama N, Kasahara Y, Takahashi M, Konno C. Structures of mahuannin A and B, hypotensive principles of Ephedra roots. Heterocycles 1982; 19: 1381-4
12. Kasahara Y, Shinomiya N, Konno C, Hikino H. Structure of mahuannin C, a hypotensive principle of Ephedra roots. Heterocycles 1983; 20: 1741-4
13. Kasahara Y, Hikino H. Structure of mahuannin D, a hypotensive principle of Ephedra roots. Heterocycles 1983; 20: 1953-6
14. Rawat MSM, Prasad D, Joshi RK, Pant G. Proanthocyanidins from Prunus armeniaca roots. Phytochemistry 1999; 50: 321-4