HCV coinfection associated with slower disease progression in HIV-infected former plasma donors naïve to art

PLoS ONE

Volumn 3, Issue 12, 2008, Pages

  Zhang, Xiaoyan ^a   Xu, Jianqing ^a,b   Peng, Hong ^a   Ma, Yan ^a   Han, Lifeng ^a   Ruan, Yuhua ^a   Su, Bing ^c   Wang, Ning ^a   Shao, Yiming ^a  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b FUDAN UNIVERSITY   (China)

^c Anhui Provincial Center for Disease Control and Prevention   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ADULT; ARTICLE; BLOOD ANALYSIS; BLOOD DONOR; CD4+ T LYMPHOCYTE; CHINA; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FOLLOW UP; HEPATITIS C; HEPATITIS C VIRUS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; PATIENT MONITORING; TOXOPLASMOSIS; VIRUS IDENTIFICATION; VIRUS LOAD; CD4 LYMPHOCYTE COUNT; COMORBIDITY; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY;

HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; TOXOPLASMA;

ADULT; ANTI-HIV AGENTS; BLOOD DONORS; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; COMORBIDITY; DISEASE PROGRESSION; FEMALE; HEPACIVIRUS; HEPATITIS C; HIV; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; VIRAL LOAD;

EID: 58049209823     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003992     Document Type: Article

References (31)

1. Benhamou Y, Bochet M, Di Martino V, Charlotte F, Azria F, et al. (1999) Liver fibrosis progression in human immunodeficiency virus and hepatitis C viru coinfected patients. The ultivirc Group. Hepatology 30: 1054-1058.
2. Bica I, McGovern B, Dhar R, Stone D, McGowan K, et al. (2001) Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection. Clin Infect Dis 32: 492-497.
3. Neau D, Trimoulet P, Winnock M, Le Bail B, Schvoerer E, et al. (2001) Impact of protease inhibitors on intrahepatic hepatitis C virus viral load. AIDS 15: 1736-1738.
4. Trimoulet P, Neau D, Le Bail B, Rullier A, Winnock M, et al. (2002) Intrahepatic HCV RNA loads in 37 HIV-HCV co-infected patients with controlled HIV infection. Journal of Medical Virology 67: 143-151.
5. Greub G, Ledergerber B, Battegay M, Grob P, Perrin L, et al. (2000) Clinical progression, survival and immune recovery during antiretroviral therapy in patients with HIV-1 and hepatitis C virus co-infection. The Swiss HIV Cohort Study. Lancet 356: 1800-1805.
6. Rauch A, Gaudieri S, Evison J, Nolan D, Cavassini M, et al. (2008) Low current and nadir CD4+ T-cell counts are associated with higher hepatitis C virus RNA levels in the Swiss HIV cohort study. Antivir Ther 13: 455-60.
7. Sulkowski S, Moore D, Mehta H, Chaisson E, Thomas L (2002) Hepatitis C and progression of HIV disease. JAMA 288: 199-206.
8. Chung RT, Evans S, Yang Y, Theodore D, Valdez H, et al. (2002) Immune recovery is associated with persistent rise in hepatitis C virus RNA, infrequent liver test flares and is not impaired by HCV in coinfected subjects. AIDS 16: 1915-1923.
9. Zhang L, Chen Z, Cao Y, Yu J, Li G, et al. (2004) Molecular characterization of human immunodeficiency virus type 1 and hepatitis C virus in paid blood donors and injection drug users in china. J Virol 78: 13591-13599.
10. Kaufman J, Jing J (2002) China and AIDS - the time to act is now. Science 296: 2339-2340.
11. Shan H, Wang J, Ren F, Zhang Y, Zhao H, et al. (2002) Blood banking in China. Lancet 360: 1770-1775.
12. Beach MV (2001) "Blood heads" and AIDS haunt China's countryside. Lancet 357: 49.
13. Xu J, Wang J, Han L, Xu C, Ruan Y, et al. (2006) Epidemiology, clinical and laboratory characteristics of currently alive HIV-1 infected former blood donors naive to antiretroviral therapy in Anhui Province, China. Chin Med J (Engl) 119: 1941-1948.
14. Wang S, Xing H, Wang J, Su B, Chen X, et al. (2007) Sequence analysis of gag and enu genes of HIV type 1 circulating in former blood donors of Fuyang city, Anhui province. Zhonghua Yi Xue Za Zhi 87: 1535-1539.
15. Yang Y, Gong J, Pan Q, Liu J, Zhang Z, et al. (2008) The Prevalence of Hepatitis C Virus (HCV) Subtypes and Their Potential Impact on HIV-1 Disease Progression in Chinese HIV-1/HCV co-infected Individuals. Chinese Journal of Microbiology and Immunology; In press.
16. McGovern H (2007) Hepatitis C in the HIV-infected patient. J Acquir Immune Defic Syndr 45: S47-56; Discussion S66-67.
17. Anderson B, Guest L, Rimland D (2004) Hepatitis C virus coinfection increases mortality in HIV-infected patients in the highly active antiretroviral therapy era: data from the HIV Atlanta VA Cohort Study. Clin Infect Dis 39: 1507-1513.
18. Dorrucci M, Valdarchi C, Suligoi B, Zaccarelli M, Sinicco A, et al. (2004) The effect of hepatitis C on progression to AIDS before and after highly active antiretroviral therapy. IDS 18: 2313-2318.
19. Klein MB, Lalonde RG, Suissa S (2003) The impact of hepatitis C virus coinfection on HIV progression before and after highly active antiretroviral therapy. J Acquir Immune Defic Syndr 33: 365-372.
20. Voirin N, Trepo C, Miailhes P, Touraine L, Chidiac C, et al. (2004) Survival in HIV-infected patients is associated with hepatitis C virus infection and injecting drug use since the use of highly active antiretroviral therapy in the Lyon observational database. J Viral Hepat 11: 559-562.
21. Rockstroh J (2006) Influence of viral hepatitis on HIV infection. J Hepatology 44: S25-27.
22. Law P, Duncombe J, Mahanontharit A, Boyd A, Ruxrungtham K, et al. (2004) Impact of viral hepatitis co-infection on response to antiretroviral therapy and HIV disease progression in the HIV-NAT cohort. AIDS 18: 1169-1177.
23. Hershow C, O'Driscoll T, Handelsman E, Pitt J, Hillyer G, Serchuck L, et al. (2005) Hepatitis C virus coinfection and HIV load, CD4+ cell percentage, and clinical progression to AIDS or death among HIV-infected women: Women and Infants Transmission Study. Clin Infect Dis 40: 859-867.
24. Morsica G, Bagaglio S, Ghezzi S, Lodrini C, Vicenzi E, et al. (2007) Hepatitis C virus coinfection in a cohort of HIV positive long-term non-progressors: possible protective effect of infecting HCV genotype on HIV disease proression. J Clin Virol 39: 82-86.
25. Shivraj S, Chattopadhya D, Grover G, Kumar A, Baveja K, et al. (2006) Role of HCV coinfection towards disease progression and survival in HIV-1 infected children: a follow-up study of 10 years. J Trop Pediatr 52: 206-211.
26. Micheloud D, Jensen J, Bellon J, Gurbindo D, de José I, et al. (2007) Slow progression of human immunodeficiency virus and hepatitis C virus disease in a cohort of coinfected children. Pediatr Infect Dis 26: 846-849.
27. Yoo W, Donfield S, Lail A, Lynn S, Daar S (2005) Effect of hepatitis C virus (HCV) genotype on HCV and HIV-1 disease. J Infect Dis 191: 4-10.
28. Morsica G, Bagaglio S, Ghezzi S, Lodrini C, Vicenzi E, et al. (2007) Hepatitis C virus coinfection in a cohort of HIV positive long-term non-progressors: possible protective effect of infecting HCV genotype on HIV disease proression. J Clin Virol 39: 82-86.
29. Bertschy S, Opravil M, Cavassini M, Bernasconi E, Schiffer V, et al. (2006) Swiss HIV Cohort Study. Discontinuation of maintenance therapy against toxoplasma encephalitis in AIDS patients with sustained response to antiretroviral therapy. Clin Microbiol Infect 12: 666-671.
30. Miro M, Lopez C, Podzamczer D, Pena M, Alberdi C, et al. (2006) Discontinuation of primary and secondary Toxoplasma gondii prophylaxis is safe in HIV-infected patients after immunological restoration with highly active antiretroviral therapy: results of an open, randomized, multicenter clinical trial. Clin Infect Dis 43: 79-89.
31. Harcourt GC, Donfield S, Gomperts E, Daar ES, Goulder P Jr, et al. (2005) Longitudinal analysis of CD8 T-cell responses to HIV and hepatitis C virus in a cohort of co-infected haemophiliacs. AIDS 19: 1135-1143.