Quantitative determination of ophiopogonin D by liquid chromatography/ electrospray ionization mass spectrometry and its pharmacokinetics in rat

Planta Medica

Volumn 74, Issue 15, 2008, Pages 1832-1836

  Xia, Chun Hua ^a,b   Sun, Jian Guo ^a   Hao, Hai Ping ^a   Wang, Guang Ji ^a   Yan, Bei ^a   Gu, Sheng Hua ^a   Zheng, Chao Nan ^a   Shang, Li Li ^a   Roberts, Michael S ^c  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANCHANG UNIVERSITY   (China)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

'SHENMAI' injection; LC ESI MS; Liliaceae; Method validation; Ophiopogon japonicus Ker Gawl.; Ophiopogonin D; Pharmacokinetics; Radix ophiopogonis

Indexed keywords

DIGOXIN; OPHIOPOGON ROOT; OPHIOPOGONIN D; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; COMPARTMENT MODEL; CONCENTRATION RESPONSE; DRUG CLEARANCE; DRUG DETERMINATION; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; GINSENG; INJECTION; ION MONITORING; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PARAMETER; PLASMA CONCENTRATION-TIME CURVE; QUANTITATIVE ASSAY; RAT; SENSITIVITY AND SPECIFICITY;

ANIMALS; CHROMATOGRAPHY, LIQUID; OPHIOPOGON; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPIROSTANS;

LILIACEAE; OPHIOPOGON JAPONICUS; RATTUS;

EID: 58049199479     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1088339     Document Type: Article

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