Abnormal endothelium-dependent microvascular dilator reactivity in pregnancies complicated by normotensive intrauterine growth restriction

American Journal of Obstetrics and Gynecology

Volumn 200, Issue 1, 2009, Pages 66.e1-66.e6

  Koopmans, Corine M ^a   Blaauw, Judith ^a   van Pampus, Maria G ^a   Rakhorst, Gerhard ^a   Aarnoudse, Jan G ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

abnormal endothelial function; acetylcholine; iontophoresis; microcirculation; normotensive intrauterine growth restriction

Indexed keywords

ACETYLCHOLINE; ENDOTHELIUM DERIVED RELAXING FACTOR; NITROPRUSSIDE SODIUM;

ADULT; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; FEMALE; HUMAN; INTRAUTERINE GROWTH RESTRICTION; IONTOPHORESIS; LASER DOPPLER FLOWMETRY; PRENATAL DISORDER; PRENATAL GROWTH; PREPREGNANCY CARE; PRIORITY JOURNAL; THIRD TRIMESTER PREGNANCY; VASODILATATION;

EID: 58049135502     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2008.07.022     Document Type: Article

References (42)

1. McIntire D.D., Bloom S.L., Casey B.M., and Leveno K.J. Birth weight in relation to morbidity among newborn infants. N Engl J Med 340 (1999) 1234-1238
2. Garite T.J., Clark R., and Thorp J.A. Intrauterine growth restriction increases morbidity and mortality among premature neonates. Am J Obstet Gynecol 191 (2004) 481-487
3. Lubchenco L.O., Hansman C., and Boyd E. Intrauterine growth as estimated from live born birth-weight data at 24-42 weeks of gestation. Pediatrics 32 (1963) 793-800
4. Resnik R. Intrauterine growth restriction. Obstet Gynecol 99 (2002) 490-496
5. Wollmann H.A. Intrauterine growth restriction: definition and etiology. Horm Res 49 (1998) 1-6
6. Aardema M.W., Oosterhof H., Timmer A., van Rooy I., and Aarnoudse J.G. Uterine artery Doppler flow and uteroplacental vascular pathology in normal pregnancies and pregnancies complicated by preeclampsia and small for gestational age fetuses. Placenta 22 (2001) 405-411
7. Ness R.B., and Sibai B.M. Shared and disparate components of the pathophysiologies of fetal growth restriction and preeclampsia. Am J Obstet Gynecol 195 (2006) 40-49
8. Villar J., Carroli G., Wojdyla D., et al. Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions?. Am J Obstet Gynecol 194 (2006) 921-931
9. Goswami D., Tannetta D.S., Magee L.A., et al. Excess syncytiotrophoblast microparticle shedding is a feature of early-onset pre-eclampsia but not normotensive intrauterine growth restriction. Placenta 27 (2006) 56-61
10. Mayhew T.M., Ohadike C., Baker P.N., Crocker I.P., Mitchell C., and Ong S.S. Stereological investigation of placental morphology in pregnancies complicated by pre-eclampsia with and without intrauterine growth restriction. Placenta 24 (2003) 219-226
11. Khong T.Y., de Wolf F., Robertson W.B., and Brosens I. Inadequate maternal vascular response to placentation in pregnancies complicated by preeclampsia and by small-for gestational age infants. Br J Obstet Gynaecol 93 (1986) 1049-1059
12. Sheppard B.L., and Bonnar J. An ultrastructural study of utero-placental spiral arteries in hypertensive and normotensive pregnancy and fetal growth retardation. Br J Obstet Gynaecol 88 (1981) 695-705
13. Roberts J.M., and Cooper D.W. Pathogenesis and genetics of pre-eclampsia. Lancet 357 (2001) 53-56
14. Sibai B., Dekker G., and Kupferminc M. Pre-eclampsia. Lancet 365 (2005) 785-799
15. Corretti M.C., Anderson T.J., Benjamin E.J., et al. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 39 (2002) 257-265
16. Raitakari O.T., and Celermajer D.S. Flow-mediated dilatation. Br J Clin Pharmacol 50 (2000) 397-404
17. Savvidou M.D., Hingorani A.D., Tsikas D., Frölich J.C., Vallance P., and Nicolaides K.H. Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia. Lancet 361 (2003) 1511-1517
18. Yoshida A., Nakao S., Kobayashi M., and Kobayashi H. Flow-mediated vasodilation and plasma fibronectin levels in preeclampsia. Hypertension 36 (2000) 400-404
19. Chambers J.C., Fusi L., Malik I.S., Haskard D.O., de Swiet M., and Kooner J.S. Association of maternal endothelial dysfunction with preclampsia. JAMA 285 (2001) 1607-1612
20. Khan F., Belch J.J., Macleod M., and Mires G. Changes in endothelial function precede the clinical disease in women in whom preeclampsia develops. Hypertension 46 (2005) 1123-1128
21. Blaauw J., Graaff R., van Pampus M.G., et al. Abnormal endothelium-dependent microvascular reactivity in recently preeclamptic women. Obstet Gynecol 105 (2005) 626-632
22. Davis R.R., Ponnampalam J., Hayman R., Baker P.N., Arulkumaran S., and Donnelly R. Microvascular vasodilator response to acetylcholine is increased in women with pre-eclampsia. BJOG 108 (2001) 610-614
23. Blaauw J., van Pampus M.G., Rakhorst G., and Aarnoudse J.G. Endothelium-dependent and -independent vasodilatation in preeclampsia and HELLP syndrome. Am J Obstet Gynecol (2006) Abstract 468
24. Kloosterman G.J. On intrauterine growth. The significance of prenatal care. Int J Gynaecol Obstet 8 (1970) 895-912
25. Snijders R.J.M., and Nicolaides K.H. Fetal biometry at 14-40 weeks' gestation. Ultrasound Obstet Gynecol 4 (1994) 34-48
26. Achaya G., Wilsgaard T., Berntsen G.K.R., Maltau J.M., and Kiserud T. Reference ranges for serial measurements of umbilical artery Doppler indices in the second half of pregnancy. Am J Obstet Gynecol 192 (2005) 937-944
27. Morris S.J., Shore A.C., and Tooke J.E. Responses of the skin microcirculation to acetylcholine and sodium nitroprusside in patients with NIDDM. Diabetologia 38 (1995) 1337-1344
28. Serne E.H., Stehouwer C.D., ter Maaten J.C., et al. Microvascular function relates to insulin sensitivity and blood pressure in normal subjects. Circulation 99 (1999) 896-902
29. de Jongh R.T., Serne E.H., IJzerman R.G., et al. Impaired microvascular function in obesity: implications for obesity-associated microangiopathy, hypertension, and insulin resistance. Circulation 109 (2004) 2529-2535
30. Kernick D.P., Tooke J.E., and Shore A.C. The biological zero signal in laser Doppler fluximetry: origins and practical implications. Pflugers Arch 437 (1999) 624-631
31. Nienhuis H.L., de Leeuw K., Smit A.J., et al. Enhanced endothelium-dependent microvascular responses in patients with Wegener's granulomatosis. J Rheumatol 34 (2007) 1875-1881
32. Johnson M.R., Anim-Nyame N., Johnson P., Sooranna S.R., and Steer P.J. Does endothelial cell activation occur with intrauterine growth restriction?. BJOG 109 (2002) 836-839
33. Ramsay J.E., Ferrell W.R., Crawford L., Wallace A.M., Greer I.A., and Sattar N. Divergent metabolic and vascular phenotypes in pre-eclampsia and intrauterine growth restriction: relevance of adiposity. J Hypertens 22 (2004) 2177-2183
34. Myers J., Mires G., Macleod M., and Baker P. In preeclampsia, the circulating factors capable of altering in vitro endothelial function precede clinical disease. Hypertension 45 (2005) 258-263
35. Agewall S., Henareh L., and Kublickiene K. Endothelial function in conduit and resistance artreries in men with coronary disease. Atherosclerosis 184 (2006) 130-136
36. Clapp B.R., Hirschfield G.M., and Storry C. Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability. Circulation 111 (2005) 1530-1536
37. Furchgott R.F., and Zawadzki J.V. The obligatory role of endothelial cell in the relaxation of arterial smooth muscle by acetylcholine. Nature 288 (1980) 373-376
38. Luksha L., Nisell H., and Kublickiene K. The mechanism of EDHF-mediated responses in subcutaneous small arteries from healthy pregnant women. Am J Physiol Reg Integr Comp Physiol 286 (2004) R1102-R1109
39. Gori T., Di Stolfo G., Sicuro S., et al. Correlation analysis between different parameters of conduit artery and microvascular vasodilation. Clin Hemorheol Microcirc 35 (2006) 509-515
40. Houben A.J., de Leeuw P.W., and Peeters L.L. Configuration of the microcirculation in pre-eclampsia: possible role of the venular system. J Hypertens 25 (2007) 1665-1670
41. Vollebregt K.C., Boer K., Mathura K.R., de Graaff J.C., Ubbink D.T., and Ince C. Impaired vascular function in women with pre-eclampsia observed with orthogonal polarisation spectral imaging. BJOG 108 (2001) 1148-1153
42. O'Brien T.E., Ray J.G., and Chan W.S. Maternal body mass index and the risk of preeclampsia: a systematic review. Epidemiology 14 (2003) 368-374