Hypoglycemic and antihyperglycemic activity of aqueous extract of diospyros peregrina fruits in normal and alloxan-induced diabetic rabbits

Pharmacologyonline

Volumn 3, Issue , 2008, Pages 250-256

  Kumar, K Eswar ^a   Mastan, S K ^a,b   Sreekanth, N ^c   Chaitanya, G ^b   Sumalatha, G ^a   Krishna, P V ^d  

^a ANDHRA UNIVERSITY   (India)

^b ROLAND INSTITUTE OF PHARMACEUTICAL SCIENCES   (India)

^c Siddharth Institute of Pharmacy   (India)

^d SHRI VISHNU COLLEGE OF PHARMACY   (India)

Author keywords

Alloxan monohydrate; Antihyperglycemia; Diabetes; Diospyros peregrina; Hypoglycemia

Indexed keywords

ALLOXAN; DIOSPYROS PEREGRINA EXTRACT; GLIBENCLAMIDE; GLUCOSE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERGLYCEMIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIABETES CONTROL; DIABETES MELLITUS; DIOSPYROS PEREGRINA; DOSE RESPONSE; DRUG ACTIVITY; FEMALE; FRUIT; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIC ACTIVITY; MALE; NONHUMAN; PERSIMMON; RABBIT;

EID: 58049108370     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Li WL, Zheng HC, Bukuru J, Dekimbe N. Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. J Ethanopharmocol 2004; 92: 1-21.
2. King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025 prevalence, numerical estimates and projections. Diabet Care 1998; 21: 1414-1431.
3. Venkatesh S, Reddy GD, Reddy BM, Ramesh M, Apparao AVN. Antihyperglycemic activity of Carulluma asttenuate. Fieoterapia 2003; 74: 274-277.
4. Valiathan MS. Healing Plants. Curr Sci. 1998; 75:1112-1122.
5. Babu V, Gangadevi T, Subramaniam A. Antihyperglycemic activity of Cassia kleinii leaf extract in glucose fed normal rats and alloxan-induced diabetic rats. Ind J Pharmacol 2002; 34: 409-415.
6. Kirtikar KR, Basu BD. Indian Medicinal Plants. In: Singh B, Singh MP, eds. Reprint edition., Vol 2. Dehradun, 1975: 1502-1504.
7. Misra PS, Misra G, Nigam SK, Mitra CR. Constituents of Diospyros peregrina fruit and seed. Phytochemistry 1971; 10: 904-905.
8. Asolkar LV, Kakkar KK, Chakre OJ. Second supplement to Glossary of Indian Medicinal Plants with active principles. Part-1 (A-K) 1st ed., Part 1. New Delhi: CSIR (PID): 1992: 279.
9. Saikat D, Sekhar KB, Ranabir S, Subash CM. Antidiabetic effects of matured fruits of Diospyros peregrina in alloxan-induced diabetic rats. Inter J Green Pharmacy, 2008: 95-99.
10. Kokate CK. Practical Pharmacognosy. New Delhi, India: Vallabh Prakashan: 1994. p.107-110.
11. Trinder P. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann Clin Biochem 1969; 6: 24.
12. Baily CJ, Flatt R. Antidiabetic Drugs, New Developments. Ind Biotech 1996; 6: 139-142.
13. Viggneri R, Pezzino V, Wang KY. Comparison of the in-vitro effect of biguanides and sulfonylureas on the insulin binding of its receptors in target cells. J Clin Endocrinol Metab 1982; 54: 95-100.
14. Grodsky GM, Epstein GH, Fanska R, Karam JH. Pancreatic action of sulfonylureas. Fed Proc 1971; 36: 2719-2728.
15. Yallow RS, Black H, Villazan M, Berson SA. Comparison of plasma insulin levels following administration of tolbutamide and glucose. Diabetes 1960; 9: 356-362.
16. Miura T, Ichhiki G, Hashimoto I, Iwamoto N, Kato M, Kubo M. Antidiabetic activity of xanthose compound, Mangiferin, Phytomedicine 2001; 8: 85-87.