Small-cell lung cancer: Translational research enroute to therapeutic advances

ONCOLOGY

Volumn 22, Issue 13, 2008, Pages

  Dowell, Jonathan ^a   Minna, John D ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMRUBICIN; ANTINEOPLASTIC AGENT; BEVACIZUMAB; CISPLATIN; CYCLOPAMINE; ETOPOSIDE; GDC 0449; IRINOTECAN; PEMETREXED; PLATINUM COMPLEX; PROTEIN BCL 2; SONIC HEDGEHOG PROTEIN; STEM CELL FACTOR RECEPTOR; THALIDOMIDE; TOPOTECAN; UNCLASSIFIED DRUG; UROKINASE RECEPTOR;

ANTINEOPLASTIC ACTIVITY; BRAIN METASTASIS; CANCER INHIBITION; CANCER RADIOTHERAPY; CANCER RESISTANCE; CANCER STAGING; CANCER STEM CELL; CANCER SURVIVAL; CLINICAL TRIAL; HUMAN; LUNG SMALL CELL CANCER; NONHUMAN; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; SKULL IRRADIATION;

ANTINEOPLASTIC AGENTS; CARCINOMA, SMALL CELL; HUMANS; LUNG NEOPLASMS; NEOPLASM STAGING; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL;

EID: 58049083778     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (6)

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2. Watkins DN, Berman DM, Burkholder SG, et al: Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 422:313-317, 2003.
3. Watkins DN, Berman DM, Baylin SB: Hedgehog signaling: Progenitor phenotype in small-cell lung cancer. Cell Cycle 2:196-198, 2003.
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5. Peacock CD, Watkins DN: Cancer stem cells and the ontogeny of lung cancer. J Clin Oncol 26:2883-2889, 2008.
6. Ohm JE, McGarvey KM, Yu X, et al: A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 39:237-242, 2007.