A novel method for determining functional LDL receptor activity in familial hypercholesterolemia: Application of the CD3/CD28 assay in lymphocytes

Clinica Chimica Acta

Volumn 400, Issue 1-2, 2009, Pages 42-47

  Tada, Hayato ^a   Kawashiri, Masa aki ^a   Noguchi, Tohru ^b   Mori, Mika ^a   Tsuchida, Masayuki ^a   Takata, Mutsuko ^a   Nohara, Atsushi ^b   Inazu, Akihiro ^b   Kobayashi, Junji ^b   Yachie, Akihiro ^b   Mabuchi, Hiroshi ^b   Yamagishi, Masakazu ^a  

^a Graduate School of Natural Science and Technology   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Anti CD3 CD28 antibody; Familial hypercholesterolemia; Heparin; K790X; Low density lipoprotein receptor activity; P664L; T lymphocyte

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; HEPARIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN RECEPTOR;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CELL CULTURE; CELL FRACTIONATION; CELL ISOLATION; CONTROL GROUP; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ENZYME ACTIVITY; ENZYME ASSAY; FAMILIAL HYPERCHOLESTEROLEMIA; FEMALE; FLOW CYTOMETRY; GENE MUTATION; HUMAN; LIPID BLOOD LEVEL; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; STUDENT T TEST; T LYMPHOCYTE; UPREGULATION;

ALLELES; ANIMALS; ANTIBODIES; ANTIGENS, CD28; ANTIGENS, CD3; BLOOD CHEMICAL ANALYSIS; FEMALE; HEPARIN; HETEROZYGOTE; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; LIPOPROTEINS; LYMPHOCYTES; MALE; MIDDLE AGED; MUTATION; RECEPTORS, LDL; SENSITIVITY AND SPECIFICITY;

EID: 57949099467     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2008.10.010     Document Type: Article

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