Characterization, selection, and development of an orally dosed drug polymorph from an enantiotropically related system

International Journal of Pharmaceutics

Volumn 366, Issue 1-2, 2009, Pages 1-13

  Katrincic, Lee M ^a   Sun, Yan T ^a   Carlton, Robert A ^a   Diederich, Ann M ^a   Mueller, Ronald L ^a   Vogt, Frederick G ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Enantiotropic phases; Physical characterization; Polymorphism; Solid state NMR; Solubility; X ray diffraction

Indexed keywords

[4 (4 CHLORO 3 FLUOROPHENYL) 2 [4 (METHYLOXY)PHENYL] 1,3 THIAZOL 5 YL]ACETIC ACID; ACETIC ACID DERIVATIVE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG SCREENING; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; ENANTIOMER; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SOLID STATE; THERMODYNAMICS;

ACETIC ACIDS; ADMINISTRATION, ORAL; CRYSTALLIZATION; DRUG STABILITY; MAGNETIC RESONANCE SPECTROSCOPY; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED; STEREOISOMERISM; TEMPERATURE; THERMODYNAMICS; THIAZOLES;

EID: 57849156179     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.08.044     Document Type: Article

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