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Volumn 48, Issue 4, 2008, Pages 1181-1186
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Simultaneous determination of lansoprazole and its metabolites 5′-hydroxy lansoprazole and lansoprazole sulphone in human plasma by LC-MS/MS: Application to a pharmacokinetic study in healthy volunteers
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Author keywords
5 Hydroxy lansoprazole; Lansoprazole; Lansoprazole sulphone; LC MS MS; Pharmacokinetics
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Indexed keywords
5' HYDROXYLANSOPRAZOLE;
DRUG METABOLITE;
INDAPAMIDE;
LANSOPRAZOLE;
LANSOPRAZOLE SULFONE;
UNCLASSIFIED DRUG;
ACCURACY;
AREA UNDER THE CURVE;
ARTICLE;
BLOOD SAMPLING;
DISTRIBUTION VOLUME;
DRUG BLOOD LEVEL;
DRUG CLEARANCE;
DRUG DETERMINATION;
DRUG HALF LIFE;
ELECTROSPRAY MASS SPECTROMETRY;
HUMAN;
LIQUID CHROMATOGRAPHY;
NORMAL HUMAN;
PRECIPITATION;
PRIORITY JOURNAL;
SENSITIVITY AND SPECIFICITY;
SINGLE DRUG DOSE;
TANDEM MASS SPECTROMETRY;
VALIDATION PROCESS;
2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES;
ACETATES;
AREA UNDER CURVE;
CHROMATOGRAPHY, LIQUID;
DRUG STABILITY;
FREEZING;
GUIDELINES AS TOPIC;
HALF-LIFE;
HUMANS;
INDAPAMIDE;
METABOLIC CLEARANCE RATE;
METHANOL;
MOLECULAR STRUCTURE;
REFERENCE STANDARDS;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
TANDEM MASS SPECTROMETRY;
UNITED STATES;
UNITED STATES FOOD AND DRUG ADMINISTRATION;
WATER;
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EID: 57849148999
PISSN: 07317085
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jpba.2008.08.034 Document Type: Article |
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Times cited : (20)
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References (11)
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