Fitting models for the joint action of two drugs using SAS(R)

Pharmaceutical Statistics

Volumn 7, Issue 4, 2008, Pages 272-284

  Whitehead, Anne ^a,c   Whitehead, John ^a   Todd, Susan ^a   Zhou, Yinghui ^a   Smith, Michael K ^b  

^a UNIVERSITY OF READING   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

Antagonism; Bliss independence; Dose response surface; Drug combination; Loewe additivity; Synergy

Indexed keywords

DRUG;

ARTICLE; CLINICAL RESEARCH; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG COMBINATION; DRUG INTERACTION; DRUG POTENCY; DRUG RESEARCH; MATHEMATICAL ANALYSIS; STATISTICAL MODEL; STATISTICAL PARAMETERS; VARIANCE;

DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS;

EID: 57849124096     PISSN: 15391604     EISSN: 15391612     Source Type: Journal    
DOI: 10.1002/pst.312     Document Type: Article

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