Association of serum lipocalin-type prostaglandin D synthase levels with subclinical atherosclerosis in untreated asymptomatic subjects

Hypertension Research

Volumn 31, Issue 10, 2008, Pages 1931-1939

  Miwa, Yoshikazu ^a   Oda, Hiroshi ^b   Shiina, Yasuhiko ^b   Shikata, Kentaro ^a   Tsushima, Motoo ^c   Nakano, Satomi ^c   Maruyama, Taro ^c   Kyotani, Shingo ^c   Eguchi, Naomi ^d   Urade, Yoshihiro ^d   Takahashi Yanaga, Fumi ^a   Morimoto, Sachio ^a   Sasaguri, Toshiyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b Maruha Nichiro Holdings Inc   (Japan)

^c KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d OSAKA BIOSCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOCALIN TYPE PROSTAGLANDIN D SYNTHASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROSTAGLANDIN D SYNTHASE; UNCLASSIFIED DRUG; ISOMERASE; LIPOCALIN; PROSTAGLANDIN R2 D ISOMERASE; PROSTAGLANDIN R2 D-ISOMERASE;

ADULT; AGE DISTRIBUTION; AGED; ANKLE BRACHIAL PULSE WAVE VELOCITY; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; BLOOD PRESSURE; BODY MASS; CARDIOVASCULAR RISK; CAROTID ARTERY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DISEASE COURSE; DYSLIPIDEMIA; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERTENSION; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; OBESITY; PATHOGENESIS; PULSE WAVE; SEX DIFFERENCE; SMOKING; ARTERY; BLOOD; BLOOD FLOW VELOCITY; CAROTID ARTERY DISEASE; ECHOGRAPHY; INTIMA; METABOLISM; MIDDLE AGED; PATHOLOGY; PULSATILE FLOW; REGRESSION ANALYSIS; RISK FACTOR; SEX RATIO; TUNICA MEDIA;

ARTERIES; BLOOD FLOW VELOCITY; CAROTID ARTERY DISEASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; HYPERTENSION; INTRAMOLECULAR OXIDOREDUCTASES; LIPOCALINS; MALE; MIDDLE AGED; PULSATILE FLOW; REGRESSION ANALYSIS; RISK FACTORS; SEX DISTRIBUTION; TUNICA INTIMA; TUNICA MEDIA;

EID: 57849116597     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.31.1931     Document Type: Article

References (23)

1. Eguchi Y, Eguchi N, Oda H, et al: Expression of lipocalin-type prostaglandin D synthase (beta-trace) in human heart and its accumulation in the coronary circulation of angina patients. Proc Natl Acad Sci U S A 1997; 94: 14689-14694.
2. Taba Y, Sasaguri T, Miyagi M, et al: Fluid shear stress induces lipocalin-type prostaglandin D2 synthase expression in vascular endothelial cells. Circ Res 2000; 86: 967-973.
3. Ragolia L, Palaia T, Koutrouby TB, Maesaka JK: Inhibition of cell cycle progression and migration of vascular smooth muscle cells by prostaglandin D2 synthase: Resistance in diabetic Goto-Kakizaki rats. Am J Physiol Cell Physiol 2004; 287: C1273-C1281.
4. Cipollone F, Fazia M, Iezzi A, et al: Balance between PGD synthase and PGE synthase is a major determinant of atherosclerotic plaque instability in humans. Arterioscler Thromb Vasc Biol 2004; 24 1259-1265.
5. Ragolia L, Palaia T, Hall CE, Maesaka JK, Eguchi N, Urade Y: Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice. J Biol Chem 2005; 280: 29946-29955.
6. Bushfield M, McNicol A, MacIntyre DE: Inhibition of platelet-activating-factor-induced human platelet activation by prostaglandin D2. Differential sensitivity of platelet transduction processes and functional responses to inhibition by cyclic AMP. Biochem J 1985; 232: 267-271.
7. Negishi M, Sugimoto Y, Ichikawa A: Prostanoid receptors and their biological actions. Prog Lipid Res 1993; 32: 417-434.
8. Nagoshi H, Uehara Y, Kanai F, et al: Prostaglandin D2 inhibits inducible nitric oxide synthase expression in rat vascular smooth muscle cells. Circ Res 1998; 82: 204-209.
9. Negoro H, Soo Shin W, Hakamada-Taguchi R, et al: Endogenous prostaglandin D2 synthesis reduces an increase in plasminogen activator inhibitor-1 following interleukin stimulation in bovine endothelial cells. J Hypertens 2002; 20: 1347-1354.
10. Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK: The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391: 79-82.
11. Jiang C, Ting AT, Seed B: PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391: 82-86.
12. Marx N, Sukhova G, Murphy C, Libby P, Plutzky J: Macrophages in human atheroma contain PPARγ: Differentiation-dependent peroxisomal proliferator-activated receptor γ (PPARγ) expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes in vitro. Am J Pathol 1998; 153: 17-23.
13. Sasaguri T, Masuda J, Shimokado K, et al: Prostaglandins A and J arrest the cell cycle of cultured vascular smooth muscle cells without suppression of c-myc expression. Exp Cell Res 1992; 200: 351-357.
14. 1 arrest and differentiation marker expression in vascular smooth muscle cells. Mol Pharmacol 2000; 58: 837-844.
15. 2-induced vascular smooth muscle cell differentiation. Biochem Biophys Res Commun 2004; 319: 163-168.
16. Hirawa N, Uehara Y, Yamakado M, et al: Lipocalin-type prostaglandin D synthase in essential hypertension. Hypertension 2002; 39: 449-454.
17. Inoue T, Takayanagi K, Morooka S, et al: Serum prostaglandin D synthase level after coronary angioplasty may predict occurrence of restenosis. Thromb Haemost 2001; 85: 165-170.
18. Oda H, Shiina Y, Seiki K, Sato N, Eguchi N, Urade Y: Development and evaluation of a practical ELISA for human urinary lipocalin-type prostaglandin D synthase. Clin Chem 2002; 48: 1445-1453.
19. Nakamura U, Iwase M, Nohara S, Kanai H, Ichikawa K, Iida M: Usefulness of brachial-ankle pulse wave velocity measurement: Correlation with abdominal aortic calcification. Hypertens Res 2003; 26: 163-167.
20. Hirawa N, Uehara Y, Ikeda T, et al: Urinary prostaglandin D synthase (beta-trace) excretion increases in the early stage of diabetes mellitus. Nephron 2001; 87: 321-327.
21. Hamano K, Totsuka Y, Ajima M, et al: Blood sugar control reverses the increase in urinary excretion of prostaglandin D synthase in diabetic patients. Nephron 2002; 92: 77-85.
22. 2 and laminar fluid shear stress stabilize c-IAP1 in vascular endothelial cells. Am J Physiol Heart Circ Physiol 2003; 285: H38-H46.
23. Miwa Y, Takiuchi S, Kamide K, et al: Identification of gene polymorphism in lipocalin-type prostaglandin D synthase and its association with carotid atherosclerosis in Japanese hypertensive patients. Biochem Biophys Res Commun 2004; 322: 428-433.