Comparison of extraction efficiencies and LC-MS-MS matrix effects using LLE and SPE methods for 19 antipsychotics in human blood

Analytical and Bioanalytical Chemistry

Volumn 393, Issue 2, 2009, Pages 727-734

  Saar, Eva ^a   Gerostamoulos, Dimitri ^a   Drummer, Olaf H ^a   Beyer, Jochen ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Antipsychotics; Blood; Extraction efficiency; LC MS MS; Matrix effects

Indexed keywords

BLOOD; SOLVENT EXTRACTION;

ANALYTES; ANTIPSYCHOTIC DRUGS; ANTIPSYCHOTICS; BLOOD SPECIMENS; BLOOD TYPES; EXTRACTION EFFICIENCY; HUMAN BLOODS; LC-MS-MS; LIQUID EXTRACTIONS; MATRIX EFFECTS; QUANTITATIVE METHODS; SOLID-PHASE EXTRACTIONS; SPE METHODS; SUDDEN DEATHS; VALIDATED METHODS;

EXTRACTION;

NEUROLEPTIC AGENT;

ARTICLE; BLOOD; COMPARATIVE STUDY; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METHODOLOGY; REFERENCE VALUE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

ANTIPSYCHOTIC AGENTS; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 57849115691     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-008-2498-6     Document Type: Article

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