Selection of yeast strains with enhanced expression of Plasmodium falciparum proteins

Molecular and Biochemical Parasitology

Volumn 163, Issue 2, 2009, Pages 119-122

  LaCount, Douglas J ^a,b   Schoenfeld, Lori W ^a   Fields, Stanley ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Plasmodium falciparum; Protein expression; Saccharomyces cerevisiae; Yeast

Indexed keywords

MESSENGER RNA; PROTEIN HRP1; PROTEIN KAP104; PROTEIN RNA15; PROTEIN URA3; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; GENE MUTATION; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE;

ANIMALS; GENETIC COMPLEMENTATION TEST; MUTATION; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE;

PLASMODIUM FALCIPARUM; SACCHAROMYCES CEREVISIAE;

EID: 57849084730     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2008.10.003     Document Type: Article

References (20)

1. Snow R.W., Guerra C.A., Noor A.M., Myint H.Y., and Hay S.I. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434 (2005) 214-217
2. Gardner M.J., Hall N., Fung E., et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419 (2002) 498-511
3. Baca A.M., and Hol W.G. Overcoming codon bias: a method for high-level overexpression of Plasmodium and other AT-rich parasite genes in Escherichia coli. Int J Parasitol 30 (2000) 113-118
4. Mehlin C., Boni E., Buckner F.S., et al. Heterologous expression of proteins from Plasmodium falciparum: results from 1000 genes. Mol Biochem Parasitol 148 (2006) 144-160
5. Vedadi M., Lew J., Artz J., et al. Genome-scale protein expression and structural biology of Plasmodium falciparum and related apicomplexan organisms. Mol Biochem Parasitol 151 (2007) 100-110
6. van Bemmelen M.X., Beghdadi-Rais C., Desponds C., et al. Expression and one-step purification of Plasmodium proteins in dictyostelium. Mol Biochem Parasitol 111 (2000) 377-390
7. Mudeppa D.G., Pang C.K., Tsuboi T., et al. Cell-free production of functional Plasmodium falciparum dihydrofolate reductase-thymidylate synthase. Mol Biochem Parasitol 151 (2007) 216-219
8. Sibley C.H., Brophy V.H., Cheesman S., et al. Yeast as a model system to study drugs effective against apicomplexan proteins. Methods 13 (1997) 190-207
9. van Hoof A., Frischmeyer P.A., Dietz H.C., and Parker R. Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295 (2002) 2262-2264
10. Anderson J.S., and Parker R.P. The 3′ to 5′ degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3′ to 5′ exonucleases of the exosome complex. EMBO J 17 (1998) 1497-1506
11. Brachmann C.B., Davies A., Cost G.J., et al. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14 (1998) 115-132
12. James P., Halladay J., and Craig E.A. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144 (1996) 1425-1436
13. Mumberg D., Muller R., and Funk M. Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene 156 (1995) 119-122
14. Shimogawa M.M., Graczyk B., Gardner M.K., et al. Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase. Curr Biol 16 (2006) 1489-1501
15. Henry M., Borland C.Z., Bossie M., and Silver P.A. Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3. Genetics 142 (1996) 103-115
16. Kessler M.M., Henry M.F., Shen E., et al. Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3′-end formation in yeast. Genes Dev 11 (1997) 2545-2556
17. Aitchison J.D., Blobel G., and Rout M.P. Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins. Science 274 (1996) 624-627
18. Hammell C.M., Gross S., Zenklusen D., et al. Coupling of termination, 3′ processing, and mRNA export. Mol Cell Biol 22 (2002) 6441-6457
19. Minvielle-Sebastia L., Preker P.J., and Keller W. RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3′-end processing factor. Science 266 (1994) 1702-1705
20. Alto N.M., Shao F., Lazar C.S., et al. Identification of a bacterial type III effector family with G protein mimicry functions. Cell 124 (2006) 133-145