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Volumn 68, Issue 18, 2008, Pages 2557-2560

Therapeutic potential of vaccines in the management of hypertension

Author keywords

CYT 006 AngQb, therapeutic use; Hypertension, treatment; Research and development; Vaccines, therapeutic use

Indexed keywords

ALDOSTERONE; ANGIOTENSIN I; ANGIOTENSIN II; CYT006 ANGQB VACCINE; KEYHOLE LIMPET HEMOCYANIN; PMD 3117; RENIN; UNCLASSIFIED DRUG;

EID: 57749203373     PISSN: 00126667     EISSN: 00126667     Source Type: Journal    
DOI: 10.2165/0003495-200868180-00002     Document Type: Review
Times cited : (10)

References (14)
  • 1
    • 34548166766 scopus 로고    scopus 로고
    • Renin: Friend or foe?
    • Sep;
    • Brown MJ. Renin: friend or foe? Heart 2007 Sep; 93 (9): 1026-33
    • (2007) Heart , vol.93 , Issue.9 , pp. 1026-1033
    • Brown, M.J.1
  • 2
    • 0242654867 scopus 로고    scopus 로고
    • Effects of different blood-pressure-lowering regimens on major cardiovascular events: Results of prospectively-designed overviews of randomised trials
    • Nov 8;
    • Turnbull F. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet 2003 Nov 8; 362 (9395): 1527-35
    • (2003) Lancet , vol.362 , Issue.9395 , pp. 1527-1535
    • Turnbull, F.1
  • 3
    • 57749184826 scopus 로고    scopus 로고
    • online, Available from URL:, Accessed 2008 Oct 23
    • National Institute for Clinical Excellence. CG34 hypertension: NICE guideline (all the recommendations) [online]. Available from URL: http://www.nice.org.uk/guidance/CG34/niceguidance/pdf/English [Accessed 2008 Oct 23]
    • CG34 hypertension: NICE guideline (all the recommendations)
  • 4
    • 24644443331 scopus 로고    scopus 로고
    • Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOTBPLA): A multicentre randomised controlled trial
    • Sep 10-16;
    • Dahlof B, Sever PS, Poulter NR, et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOTBPLA): a multicentre randomised controlled trial. Lancet 2005 Sep 10-16; 366 (9489): 895-906
    • (2005) Lancet , vol.366 , Issue.9489 , pp. 895-906
    • Dahlof, B.1    Sever, P.S.2    Poulter, N.R.3
  • 5
    • 0036898286 scopus 로고    scopus 로고
    • Hyperaldosteronism among Black and White subjects with resistant hypertension
    • Dec 1;
    • Calhoun DA, Nishizaka MK, Zaman MA, et al. Hyperaldosteronism among Black and White subjects with resistant hypertension. Hypertension 2002 Dec 1; 40 (6): 892-6
    • (2002) Hypertension , vol.40 , Issue.6 , pp. 892-896
    • Calhoun, D.A.1    Nishizaka, M.K.2    Zaman, M.A.3
  • 6
    • 34547559617 scopus 로고    scopus 로고
    • Hood SJ, Taylor KP, Ashby MJ, et al. The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind cross-over trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. Circulation 2007 Jul 17; 116 (3): 268-75
    • Hood SJ, Taylor KP, Ashby MJ, et al. The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind cross-over trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. Circulation 2007 Jul 17; 116 (3): 268-75
  • 7
    • 0025688030 scopus 로고
    • Brief angiotensin converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long-treatments term
    • Dec;
    • Harrap SB, Van der Merwe WM, Griffin SA, et al. Brief angiotensin converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long-treatments term. Hypertension 1990 Dec; 16 (6): 603-14
    • (1990) Hypertension , vol.16 , Issue.6 , pp. 603-614
    • Harrap, S.B.1    Van der Merwe, W.M.2    Griffin, S.A.3
  • 8
    • 4043179763 scopus 로고    scopus 로고
    • Renin-angiotensin vaccine: Old story, new project 'efficacy versus safety'
    • Aug;
    • Michel J-B. Renin-angiotensin vaccine: old story, new project 'efficacy versus safety'. Clin Sci 2004 Aug; 107 (2): 145-7
    • (2004) Clin Sci , vol.107 , Issue.2 , pp. 145-147
    • Michel, J.-B.1
  • 9
    • 34447521458 scopus 로고    scopus 로고
    • Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: A randomised, double-blind trial
    • Jul 21;
    • Oparil S, Yarows SA, Patel S, et al. Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial. Lancet 2007 Jul 21; 370 (9583): 221-9
    • (2007) Lancet , vol.370 , Issue.9583 , pp. 221-229
    • Oparil, S.1    Yarows, S.A.2    Patel, S.3
  • 10
    • 4043116249 scopus 로고    scopus 로고
    • Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects
    • Aug;
    • Brown MJ, Coltart J, Gunewardena K, et al. Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects. Clin Sci (Lond) 2004 Aug; 107 (2): 167-73
    • (2004) Clin Sci (Lond) , vol.107 , Issue.2 , pp. 167-173
    • Brown, M.J.1    Coltart, J.2    Gunewardena, K.3
  • 11
    • 40049106627 scopus 로고    scopus 로고
    • Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: A double-blind, randomised, placebo-controlled phase IIa study
    • Mar 8;
    • Tissot AC, Maurer P, Nussberger J, et al. Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study. Lancet 2008 Mar 8; 371 (9615): 821-7
    • (2008) Lancet , vol.371 , Issue.9615 , pp. 821-827
    • Tissot, A.C.1    Maurer, P.2    Nussberger, J.3
  • 12
    • 50349094508 scopus 로고    scopus 로고
    • Aug 12;
    • Brown MJ. Aliskiren. Circulation 2008 Aug 12; 118 (7): 773-84
    • (2008) Circulation , vol.118 , Issue.7 , pp. 773-784
    • Aliskiren, B.M.J.1
  • 13
    • 33845362874 scopus 로고    scopus 로고
    • A vaccine for hypertension based on virus-like particles: Preclinical efficacy and phase I safety and immunogenicity
    • Jan;
    • Ambuhl PM, Tissot AC, Fulurija A, et al. A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity. J Hypertens 2007 Jan; 25 (1): 63-72
    • (2007) J Hypertens , vol.25 , Issue.1 , pp. 63-72
    • Ambuhl, P.M.1    Tissot, A.C.2    Fulurija, A.3
  • 14
    • 0034018039 scopus 로고    scopus 로고
    • Active immunization with angiotensin I peptide analogue vaccines selectively reduces the pressor effects of exogenous angiotensin I in conscious rats
    • Mar;
    • Gardiner SM, Auton TR, Downham MR, et al. Active immunization with angiotensin I peptide analogue vaccines selectively reduces the pressor effects of exogenous angiotensin I in conscious rats. Br J Pharmacol 2000 Mar; 129 (6): 1178-82
    • (2000) Br J Pharmacol , vol.129 , Issue.6 , pp. 1178-1182
    • Gardiner, S.M.1    Auton, T.R.2    Downham, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.