Human mutation in the anti-apoptotic heat shock protein 20 abrogates its cardioprotective effects

Journal of Biological Chemistry

Volumn 283, Issue 48, 2008, Pages 33465-33471

  Nicolaou, Persoulla ^a   Knöll, Ralph ^b   Haghighi, Kobra ^a   Fan, Guo Chang ^a   Dorn II, Gerald W ^a   Hasenfuß, Gerd ^b   Kranias, Evangelia G ^a,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c BIOMEDICAL RESEARCH FOUNDATION   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CARDIOLOGY; CELL DEATH; CHEMICAL REACTIONS; NUCLEIC ACIDS; ORGANIC ACIDS; PHOSPHORYLATION; PROGRAMMING THEORY; PROTEINS;

APOPTOSIS; BENEFICIAL EFFECTS; CARDIOMYOCYTES; CARDIOPROTECTION; CARDIOPROTECTIVE EFFECTS; CELLULAR STRESSES; CODING REGIONS; DILATED CARDIOMYOPATHIES; DNA FRAGMENTATIONS; GENETIC VARIANTS; GREEN FLUORESCENT PROTEINS; HEART DISEASES; HEAT SHOCK PROTEINS; HOECHST; IN VITRO; ISOPROTERENOL; PROLINE RESIDUES; PROTEIN KINASES; SIGNIFICANT ATTENUATIONS; SMALL HEAT SHOCK PROTEINS; STRUCTURAL ALTERATIONS;

ANIMAL CELL CULTURE;

CYCLIC AMP DEPENDENT PROTEIN KINASE; GREEN FLUORESCENT PROTEIN; HEAT SHOCK PROTEIN 20; ISOPRENALINE; LEUCINE; PROLINE; SERINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRESS; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DNA FRAGMENTATION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC VARIABILITY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HETEROZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; RAT; REPERFUSION INJURY; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; APOPTOSIS; CARDIOMYOPATHY, DILATED; CARDIOTONIC AGENTS; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA FRAGMENTATION; FEMALE; HSP20 HEAT-SHOCK PROTEINS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; ISOPROTERENOL; MALE; MUTATION, MISSENSE; MYOCYTES, CARDIAC; OPEN READING FRAMES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY;

ADENOVIRIDAE; RATTUS;

EID: 57749119543     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802307200     Document Type: Article

References (34)

1. Young, J. C., Agashe, V. R., Siegers, K., and Hartl, F. U. (2004) Nat. Rev. Mol. Cell Biol. 5, 781-791
2. Currie, R. W. (1987) J. Mol. Cell. Cardiol. 19, 795-808
3. Kato, K., Goto, S., Inaguma, Y., Hasegawa, K., Morishita, R., and Asano, T. (1994) J. Biol. Chem. 269, 15302-15309
4. Dillmann, W. H., Mehta, H. B., Barrieux, A., Guth, B. D., Neeley, W. E., and Ross, J., Jr. (1986) Circ. Res. 59, 110-114
5. Donnelly, T. J., Sievers, R. E., Vissern, F. L., Welch, W. J., and Wolfe, C. L. (1992) Circulation 85, 769-778
6. White, F. P., and White, S. R. (1986) Cardiovasc. Res. 20, 512-515
7. Fan, G. C., Chu, G., Mitton, B., Song, Q., Yuan, Q., and Kranias, E. G. (2004) Circ. Res. 94, 1474-1482
8. Kappé, G., Franck, E., Verschuure, P., Boelens, W. C., Leunissen, J. A., and de Jong, W. W. (2003) Cell Stress Chaperones 8, 53-61
9. Narberhaus, F. (2002) Microbiol. Mol. Biol. Rev. 66, 64-93
10. Chu, G., Egnaczyk, G. F., Zhao, W., Jo, S. H., Fan, G. C., Maggio, J. E., Xiao, R. P., and Kranias, E. G. (2004) Circ. Res. 94, 184-193
11. Boluyt, M. O., Brevick, J. L., Rogers, D. S., Randall, M. J., Scalia, A. F., and Li, Z. B. (2006) Proteomics 6, 3154-3169
12. Dohke, T., Wada, A., Isono, T., Fujii, M., Yamamoto, T., Tsutamoto, T., and Horie, M. (2006) J. Card. Fail. 12, 77-84
13. Islamovic, E., Duncan, A., Bers, D. M., Gerthoffer, W. T., and Mestril, R. (2007) J. Mol. Cell. Cardiol. 42, 862-869
14. Zhu, Y. H., Ma, T. M., and Wang, X. (2005) Acta Pharmacol. Toxicol. 26, 1193-1200
15. Zhu, Y. H., and Wang, X. (2005) Acta Pharm. Sin. 26, 1076-1080
16. Fan, G. C., Ren, X., Qian, J., Yuan, Q., Nicolaou, P., Wang, Y., Jones, W. K., Chu, G., and Kranias, E. G. (2005) Circulation 111, 1792-1799
17. Fan, G. C., Yuan, Q., Song, G., Wang, Y., Chen, G., Qian, J., Zhou, X., Lee, Y. J., Ashraf, M., and Kranias, E. G. (2006) Circ. Res. 99, 1233-1242
18. De Celle, T., Vanrobaeys, F., Lijnen, P., Blankesteijn, W. M., Heeneman, S., Van Beeumen, J., Devreese, B., Smits, J. F., and Janssen, B. J. (2005) Exp. Physiol. 90, 593-606
19. Unneberg, P., Merelo, J. J., Chacón, P., and Morán, F. (2001) Proteins 42, 460-470
20. Rodriguez, P., Mitton, B., Waggoner, J. R., and Kranias, E. G. (2006) J. Biol. Chem. 281, 38599-38608
21. Qin, Y., Vanden Hoek, T. L., Wojcik, K., Anderson, T., Li, C., Shao, Z., Becker, L. B., and Hamann, K. J. (2004) Am. J. Physiol. 286, H2280-H2286
22. van de Klundert, F. A., Smulders, R. H., Gijsen, M. L., Lindner, R. A., Jaenicke, R., Carver, J. A., and de Jong, W. W. (1998) Eur. J. Biochem. 258, 1014-1021
23. Merck, K. B., Groenen, P. J., Voorter, C. E., de Haard-Hoekman, W. A., Horwitz, J., Bloemendal, H., and de Jong, W. W. (1993) J. Biol. Chem. 268, 1046-1052
24. Kim, M. V., Seit-Nebi, A. S., Marston, S. B., and Gusev, N. B. (2004) Biochem. Biophys. Res. Commun. 315, 796-801
25. Kim, K. K., Kim, R., and Kim, S. H. (1998) Nature 394, 595-599
26. Garcia-Ranea, J. A., Mirey, G., Camonis, J., and Valencia, A. (2002) FEBS Lett. 529, 162-167
27. Pipkin, W., Johnson, J. A., Creazzo, T. L., Burch, J., Komalavilas, P., and Brophy, C. (2003) Circulation 107, 469-476
28. Fontaine, J. M., Sun, X., Benndorf, R., and Welsh, M. J. (2005) Biochem. Biophys. Res. Commun. 337, 1006-1011
29. Sharov, V. G., Sabbah, H. N., Shimoyama, H., Goussev, A. V., Lesch, M., and Goldstein, S. (1996) Am. J. Pathol. 148, 141-149
30. Teiger, E., Than, V. D., Richard, L., Wisnewsky, C., Tea, B. S., Gaboury, L., Tremblay, J., Schwartz, K., and Hamet, P. (1996) J. Clin. Investig. 97, 2891-2897
31. Li, Z., Bing, O. H., Long, X., Robinson, K. G., and Lakatta, E. G. (1997) Am. J. Physiol. 272, H2313-H2319
32. Olivetti, G., Abbi, R., Quaini, F., Kajstura, J., Cheng, W., Nitahara, J. A., Quaini, E., Di Loreto, C., Beltrami, C. A., Krajewski, S., Reed, J. C., and Anversa, P. (1997) N. Engl. J. Med. 336, 1131-1141
33. Guerra, S., Leri, A., Wang, X., Finato, N., Di Loreto, C., Beltrami, C. A., Kajstura, J., and Anversa, P. (1999) Circ. Res. 85, 856-866
34. Wencker, D., Chandra, M., Nguyen, K., Miao, W., Garantziotis, S., Factor, S. M., Shirani, J., Armstrong, R. C., and Kitsis, R. N. (2003) J. Clin. Investig. 111, 1497-1504