-
1
-
-
0035951825
-
The reactive oxygen species-and Michael acceptor-inducible human aldo-keto reductase AKR1C1 reduces the alpha,beta-unsaturated aldehyde 4-hydroxy-2-nonenal to 1,4-dihydroxy-2-nonene
-
Burczynski M.E., Sridhar G.R., Palackal N.T., and Penning T.M. The reactive oxygen species-and Michael acceptor-inducible human aldo-keto reductase AKR1C1 reduces the alpha,beta-unsaturated aldehyde 4-hydroxy-2-nonenal to 1,4-dihydroxy-2-nonene. J. Biol. Chem. 276 4 (2001) 2890-2897
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.4
, pp. 2890-2897
-
-
Burczynski, M.E.1
Sridhar, G.R.2
Palackal, N.T.3
Penning, T.M.4
-
2
-
-
0032902145
-
Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis
-
Kruman I.I., and Mattson M.P. Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis. J. Neurochem. 72 2 (1999) 529-540
-
(1999)
J. Neurochem.
, vol.72
, Issue.2
, pp. 529-540
-
-
Kruman, I.I.1
Mattson, M.P.2
-
3
-
-
11144353586
-
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease
-
Lustbader J.W., Cirilli M., Lin C., Xu H.W., Takuma K., Wang N., Caspersen C., Chen X., Pollak S., Chaney M., Trinchese F., Liu S., Gunn-Moore F., Lue L.F., Walker D.G., Kuppusamy P., Zewier Z.L., Arancio O., Stern D., Yan S.S., and Wu H. ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science 304 5669 (2004) 448-452
-
(2004)
Science
, vol.304
, Issue.5669
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
Trinchese, F.11
Liu, S.12
Gunn-Moore, F.13
Lue, L.F.14
Walker, D.G.15
Kuppusamy, P.16
Zewier, Z.L.17
Arancio, O.18
Stern, D.19
Yan, S.S.20
Wu, H.21
more..
-
4
-
-
33646152108
-
Mitochondria is a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression
-
Manczak M., Anekonda T.S., Henson E., Park B.S., Quinn J., and Reddy P.H. Mitochondria is a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. Hum. Mol. Genet. 15 9 (2006) 1437-1449
-
(2006)
Hum. Mol. Genet.
, vol.15
, Issue.9
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
Park, B.S.4
Quinn, J.5
Reddy, P.H.6
-
5
-
-
0031020993
-
Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation
-
Mark R.J., Pang Z., Geddes J.W., Uchida K., and Mattson M.P. Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. J. Neurosci. 17 3 (1997) 1046-1054
-
(1997)
J. Neurosci.
, vol.17
, Issue.3
, pp. 1046-1054
-
-
Mark, R.J.1
Pang, Z.2
Geddes, J.W.3
Uchida, K.4
Mattson, M.P.5
-
6
-
-
0033006380
-
The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin
-
Neely M.D., Sidell K.R., Graham D.G., and Montine T.J. The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin. J. Neurochem. 72 6 (1999) 2323-2333
-
(1999)
J. Neurochem.
, vol.72
, Issue.6
, pp. 2323-2333
-
-
Neely, M.D.1
Sidell, K.R.2
Graham, D.G.3
Montine, T.J.4
-
7
-
-
0037342862
-
Deficiency in a mitochondrial aldehyde dehydrogenase increases vulnerability to oxidative stress in PC12 cells
-
Ohsawa I., Nishimaki K., Yasuda C., Kamino K., and Ohta S. Deficiency in a mitochondrial aldehyde dehydrogenase increases vulnerability to oxidative stress in PC12 cells. J. Neurochem. 84 5 (2003) 1110-1117
-
(2003)
J. Neurochem.
, vol.84
, Issue.5
, pp. 1110-1117
-
-
Ohsawa, I.1
Nishimaki, K.2
Yasuda, C.3
Kamino, K.4
Ohta, S.5
-
8
-
-
0344393083
-
A multi-functional organelle mitochondrion is involved in cell death, proliferation and disease
-
Ohta S. A multi-functional organelle mitochondrion is involved in cell death, proliferation and disease. Curr. Med. Chem. 10 23 (2003) 2485-2494
-
(2003)
Curr. Med. Chem.
, vol.10
, Issue.23
, pp. 2485-2494
-
-
Ohta, S.1
-
9
-
-
0033004618
-
The lipid peroxidation product 4-hydroxynonenal impairs glutamate and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells
-
Pedersen W.A., Cashman N.R., and Mattson M.P. The lipid peroxidation product 4-hydroxynonenal impairs glutamate and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells. Exp. Neurol. 155 1 (1999) 1-10
-
(1999)
Exp. Neurol.
, vol.155
, Issue.1
, pp. 1-10
-
-
Pedersen, W.A.1
Cashman, N.R.2
Mattson, M.P.3
-
10
-
-
33746189654
-
Brain glucose sensing: a subtle mechanism
-
Penicaud L., Leloup C., Fioramonti X., Lorsignol A., and Benani A. Brain glucose sensing: a subtle mechanism. Curr. Opin. Clin. Nutr. Metab. Care 9 4 (2006) 458-462
-
(2006)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.9
, Issue.4
, pp. 458-462
-
-
Penicaud, L.1
Leloup, C.2
Fioramonti, X.3
Lorsignol, A.4
Benani, A.5
-
11
-
-
0030989545
-
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
-
Sayre L.M., Zelasko D.A., Harris P.L., Perry G., Salomon R.G., and Smith M.A. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J. Neurochem. 68 5 (1997) 2092-2097
-
(1997)
J. Neurochem.
, vol.68
, Issue.5
, pp. 2092-2097
-
-
Sayre, L.M.1
Zelasko, D.A.2
Harris, P.L.3
Perry, G.4
Salomon, R.G.5
Smith, M.A.6
-
12
-
-
0028123071
-
Alzheimer's disease: a central role for amyloid
-
Selkoe D.J. Alzheimer's disease: a central role for amyloid. J. Neuropathol. Exp. Neurol. 53 5 (1994) 438-447
-
(1994)
J. Neuropathol. Exp. Neurol.
, vol.53
, Issue.5
, pp. 438-447
-
-
Selkoe, D.J.1
-
13
-
-
0026085762
-
Beta oxidation of fatty acids
-
Schulz H. Beta oxidation of fatty acids. Biochim. Biophys. Acta 1081 2 (1991) 109-120
-
(1991)
Biochim. Biophys. Acta
, vol.1081
, Issue.2
, pp. 109-120
-
-
Schulz, H.1
-
14
-
-
0026713818
-
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation
-
Schulze-Osthoff K., Bakker A.C., Vanhaesebroeck B., Beyaert R., Jacob W.A., and Fiers W. Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation. J. Biol. Chem. 267 2 (1992) 5317-5323
-
(1992)
J. Biol. Chem.
, vol.267
, Issue.2
, pp. 5317-5323
-
-
Schulze-Osthoff, K.1
Bakker, A.C.2
Vanhaesebroeck, B.3
Beyaert, R.4
Jacob, W.A.5
Fiers, W.6
-
15
-
-
8644286341
-
Alcohol dehydrogenase two variant is associated with cerebral infarction and lacunae
-
Suzuki Y., Fujisawa M., Ando F., Niino N., Ohsawa I., Shimokata H., and Ohta S. Alcohol dehydrogenase two variant is associated with cerebral infarction and lacunae. Neurology 63 9 (2004) 1711-1713
-
(2004)
Neurology
, vol.63
, Issue.9
, pp. 1711-1713
-
-
Suzuki, Y.1
Fujisawa, M.2
Ando, F.3
Niino, N.4
Ohsawa, I.5
Shimokata, H.6
Ohta, S.7
-
16
-
-
19944433845
-
Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways
-
Tamagno E., Parola M., Bardini P., Piccini A., Borghi R., Guglielmotto M., Santoro G., Davit A., Danni O., Smith M.A., Perry G., and Tabaton M. Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways. J. Neurochem. 92 3 (2005) 628-636
-
(2005)
J. Neurochem.
, vol.92
, Issue.3
, pp. 628-636
-
-
Tamagno, E.1
Parola, M.2
Bardini, P.3
Piccini, A.4
Borghi, R.5
Guglielmotto, M.6
Santoro, G.7
Davit, A.8
Danni, O.9
Smith, M.A.10
Perry, G.11
Tabaton, M.12
-
17
-
-
0026606054
-
Modification of Histidine Residues in Proteins by Reaction with 4-Hydroxynonenal
-
Uchida K., and Stadtman E.R. Modification of Histidine Residues in Proteins by Reaction with 4-Hydroxynonenal. Proc. Nat. Acad. Sci. U.S.A. 89 10 (1992) 4544-4548
-
(1992)
Proc. Nat. Acad. Sci. U.S.A.
, vol.89
, Issue.10
, pp. 4544-4548
-
-
Uchida, K.1
Stadtman, E.R.2
-
18
-
-
33744935554
-
Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease
-
Williams T.I., Lynn B.C., Markesbery W.R., and Lovell M.A. Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease. Neurobiol. Aging 27 8 (2006) 1094-1099
-
(2006)
Neurobiol. Aging
, vol.27
, Issue.8
, pp. 1094-1099
-
-
Williams, T.I.1
Lynn, B.C.2
Markesbery, W.R.3
Lovell, M.A.4
-
19
-
-
0013079948
-
An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease
-
Yan S.D., Fu J., Soto C., Chen X., Zhu H., Al-Mohanna F., Collison K., Zhu A., Stern E., Saido T., Tohyama M., Ogawa S., Roher A., and Stern D. An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease. Nature 389 6652 (1997) 689-695
-
(1997)
Nature
, vol.389
, Issue.6652
, pp. 689-695
-
-
Yan, S.D.1
Fu, J.2
Soto, C.3
Chen, X.4
Zhu, H.5
Al-Mohanna, F.6
Collison, K.7
Zhu, A.8
Stern, E.9
Saido, T.10
Tohyama, M.11
Ogawa, S.12
Roher, A.13
Stern, D.14
-
20
-
-
16244392645
-
Multiple functions of type 10 17beta-hydroxysteroid dehydrogenase
-
Yang S.Y., He X.Y., and Schulz H. Multiple functions of type 10 17beta-hydroxysteroid dehydrogenase. Trends Endocrinol. Metab. 16 4 (2005) 167-175
-
(2005)
Trends Endocrinol. Metab.
, vol.16
, Issue.4
, pp. 167-175
-
-
Yang, S.Y.1
He, X.Y.2
Schulz, H.3
|