Packing density, permeability, and separation efficiency of packed microchips at different particle-aspect ratios

Journal of Chromatography A

Volumn 1216, Issue 2, 2009, Pages 264-273

  Jung, Stephanie ^a   Ehlert, Steffen ^a   Mora, Jose Angel ^b   Kraiczek, Karsten ^b   Dittmann, Monika ^b   Rozing, Gerard P ^b   Tallarek, Ulrich ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b AGILENT TECHNOLOGIES   (Germany)

Author keywords

Aspect ratio; Column performance; Hydraulic permeability; Microchip HPLC; Particle size distribution; Particle packed microchips; Porosity

Indexed keywords

ASPECT RATIO; CAPILLARITY; HYDRAULICS; LIQUIDS; MICROPROCESSOR CHIPS; PARTICLE SIZE; PARTICLE SIZE ANALYSIS; POROSITY; PRESSURE DROP; SEPARATION; SILICA; SIZE DISTRIBUTION; SOLIDS; STAINLESS STEEL;

COLUMN PERFORMANCE; HYDRAULIC PERMEABILITY; MICROCHIP-HPLC; PARTICLE SIZE DISTRIBUTION; PARTICLE-PACKED MICROCHIPS;

INTEGRATED CIRCUITS;

SILICON DIOXIDE; STAINLESS STEEL;

ARTICLE; DEVICE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDRAULIC PERMEABILITY; MICROCHIP; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; SEPARATION TECHNIQUE; ULTRAVIOLET RADIATION;

ALGORITHMS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IMIDES; LINEAR MODELS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; PERMEABILITY; PHYSICOCHEMICAL PHENOMENA; POROSITY; SILICON DIOXIDE;

EID: 57749100967     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.11.073     Document Type: Article

References (60)

1. Rozing G. LC-GC Eur. 16 (2003) 14
2. Hernández-Borges J., Aturki Z., Rocco A., and Fanali S. J. Sep. Sci. 30 (2007) 1589
3. Saz J.M., and Marina M.L. J. Sep. Sci. 31 (2008) 446
4. Smith R.D., Shen Y.F., and Tang K.Q. Acc. Chem. Res. 37 (2004) 269
5. Coster S., and Verpoorte E. Lab Chip 7 (2007) 1394
6. Reichmuth D.S., Shepodd T.J., and Kirby B.J. Anal. Chem. 77 (2005) 6947
7. Ro K.W., Liu J., and Knapp D.R. J. Chromatogr. A 1111 (2006) 40
8. Carlier J., Arscott S., Thomy V., Camart J.C., Cren-Olivé C., and Le Gac S. J. Chromatogr. A 1071 (2005) 213
9. Yang Y., Li C., Kameoka J., Lee K.H., and Craighead H.G. Lab Chip 5 (2005) 869
10. Mair D.A., Geiger E., Pisano A.P., Fréchet J.M.J., and Svec F. Lab Chip 6 (2006) 1346
11. Ishida A., Yoshikawa T., Natsume M., and Kamidate T. J. Chromatogr. A 1132 (2006) 90
12. Liu J., Ro K.W., Nayak R., and Knapp D.R. Int. J. Mass Spectrom. 259 (2007) 65
13. Levkin P.A., Eeltink S., Stratton T.R., Brennen R., Robotti K., Yin H., Killeen K., Svec F., and Fréchet J.M.J. J. Chromatogr. A 1200 (2008) 55
14. Xie J., Miao Y., Shih J., Tai Y.-C., and Lee T.D. Anal. Chem. 77 (2005) 6947
15. Yin H., Killeen K., Brennen R., Sobek D., Werlich M., and van de Goor T. Anal. Chem. 77 (2005) 527
16. Lazar I.M., Trisiripisal P., and Sarvaiya H.A. Anal. Chem. 78 (2006) 5513
17. Shih C.-Y., Chen Y., Xie J., He Q., and Tai Y.-C. J. Chromatogr. A 127 (2006) 272
18. Gaspar A., Piyasena M.E., and Gomez F.A. Anal. Chem. 79 (2007) 7906
19. Ehlert S., Kraiczek K., Mora J.-A., Dittmann M., Rozing G.P., and Tallarek U. Anal. Chem. 80 (2008) 5945
20. Neue U.D. HPLC Columns: Theory, Technology, and Practice (1997), Wiley-VCH, New York
21. Poppe H. J. Chromatogr. A 948 (2002) 3
22. Dutta D., Ramachandran A., and Leighton D.T. Microfluid. Nanofluid. 2 (2006) 275
23. Ajdari A., Bontoux N., and Stone H.A. Anal. Chem. 78 (2006) 387
24. Bontoux N., Pépin A., Chen Y., Ajdari A., and Stone H.A. Lab Chip 6 (2006) 930
25. Zholkovskij E.K., and Masliyah J.H. Chem. Eng. Sci. 61 (2006) 4155
26. Eghbali H., and Desmet G. J. Sep. Sci. 30 (2007) 1377
27. Bahrami M., Yovanovich M.M., and Culham J.R. Int. J. Heat Mass Transfer 50 (2007) 2492
28. Giddings J.C. Dynamics of Chromatography. Part 1. Principles and Theory (1965), Marcel Dekker, New York
29. Tallarek U., Bayer E., and Guiochon G. J. Am. Chem. Soc. 120 (1998) 1494
30. Kandhai D., Hlushkou D., Hoekstra A.G., Sloot P.M.A., Van As H., and Tallarek U. Phys. Rev. Lett. 88 (2002) 234501
31. de Klerk A. AIChE J. 49 (2003) 2022
32. Maier R.S., Kroll D.M., Bernard R.S., Howington S.E., Peters J.F., and Davis H.T. Phys. Fluids 15 (2003) 3795
33. Maier R.S., Kroll D.M., and Davis H.T. AIChE J. 53 (2007) 527
34. Rozing G., van de Goor T., Yin H., Killeen K., Glatz B., Kraiczek K., and Lauer H.H. J. Sep. Sci. 27 (2004) 1391
35. Khirevich S., Höltzel A., Hlushkou D., and Tallarek U. Anal. Chem. 79 (2007) 9340
36. Khirevich S., Höltzel A., Hlushkou D., Seidel-Morgenstern A., and Tallarek U. Lab Chip 8 (2008) 1801
37. Vissers J.P.C., Claessens H.A., Laven J., and Cramers C.A. Anal. Chem. 67 (1995) 2103
38. Halász I., and Martin K. Angew. Chem. Int. Ed. Engl. 17 (1978) 901
39. Yau W.W., Kirkland J.J., and Bly D.D. Modern Size-Exclusion Liquid Chromatography (1979), Wiley, New York
40. Guan H., and Guiochon G. J. Chromatogr. A 731 (1996) 27
41. Dullien F.A.L. Porous Media - Fluid Transport and Pore Structure (1991), Academic Press, San Diego, CA
42. Hlushkou D., and Tallarek U. J. Chromatogr. A 1126 (2006) 70
43. Carman P.C. Flow of Gases Through Porous Media (1956), Academic Press, New York
44. Ehlert S., Rösler T., and Tallarek U. J. Sep. Sci. 31 (2008) 1719
45. Melander W.R., and Horváth Cs. High Performance Liquid Chromatography-Advances and Perspectives (1980), Academic Press, New York
46. Li Y., and Park C.-W. Ind. Eng. Chem. Res. 37 (1998) 2005
47. Cabooter D., Billen J., Terryn H., Lynen F., Sandra P., and Desmet G. J. Chromatogr. A 1178 (2008) 108
48. Winterberg M., and Tsotsas E. AlChE J. 46 (2000) 1084
49. Eisfeld B., and Schnitzlein K. Chem. Eng. Sci. 56 (2001) 4321
50. Di Felice R., and Gibilaro L.G. Chem. Eng. Sci. 59 (2004) 3037
51. Giese M., Rottschäfer K., and Vortmeyer D. AIChE J. 44 (1998) 484
52. Li J., and Carr P.W. Anal. Chem. 69 (1997) 2530
53. loc. cit. [20], p. 83.
54. Cabooter D., Billen J., Terryn H., Lynen F., Sandra P., and Desmet G. J. Chromatogr. A 1204 (2008) 1
55. Billen J., Guillarme D., Rudaz S., Veuthey J.-L., Ritchie H., Grady B., and Desmet G. J. Chromatogr. A 1161 (2007) 224
56. Karlsson K.-E., and Novotny M. Anal. Chem. 60 (1988) 1662
57. Kennedy R.T., and Jorgenson J.W. Anal. Chem. 61 (1989) 1128
58. Li W., Pyo D., Wan Y., Ibaňez E., Malik A., and Lee M.L. J. Microcol. Sep. 8 (1996) 259
59. Hsieh S., and Jorgenson J.W. Anal. Chem. 68 (1996) 1212
60. Eeltink S., Rozing G.P., Schoenmakers P.J., and Kok W.Th. J. Chromatogr. A 1044 (2004) 311