Identification of small molecules that inhibit GSK-3β through virtual screening

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 2, 2009, Pages 533-537

  Kang, Nam Sook ^a   Lee, Gil Nam ^a   Kim, Chi Hyun ^a   Bae, Myung Ae ^a   Kim, Ikyon ^a   Cho, Young Sik ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Glycogen synthase kinase 3 ; Inhibitor; Thiadiazolidinones; Virtual screening

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; KRM 189; KRM 191; UNCLASSIFIED DRUG;

ARTICLE; DRUG EFFECT; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; IC 50; STRUCTURE ANALYSIS;

BINDING, COMPETITIVE; COMPUTER SIMULATION; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 57749094583     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.10.120     Document Type: Article

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