-
1
-
-
0030797902
-
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
-
Anzick SL, Kononen J, Walker RL, Azorsa DO, Tanner MM, Guan XY, Sauter G, Kallioniemi OP, Trent JM & Meltzer PS 1997 AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science 277 965-968.
-
(1997)
Science
, vol.277
, pp. 965-968
-
-
Anzick, S.L.1
Kononen, J.2
Walker, R.L.3
Azorsa, D.O.4
Tanner, M.M.5
Guan, X.Y.6
Sauter, G.7
Kallioniemi, O.P.8
Trent, J.M.9
Meltzer, P.S.10
-
3
-
-
0034667952
-
HER-2/neu and p53 expression versus tamoxifen resistance in estrogen receptor-positive, node-positive breast cancer
-
Berry DA, Muss HB, Thor AD, Dressler L, Liu ET, Broadwater G, Budman DR, Henderson IC, Barcos M, Hayes D et al. 2000 HER-2/neu and p53 expression versus tamoxifen resistance in estrogen receptor-positive, node-positive breast cancer. Journal of Clinical Oncology 18 3471-3479.
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 3471-3479
-
-
Berry, D.A.1
Muss, H.B.2
Thor, A.D.3
Dressler, L.4
Liu, E.T.5
Broadwater, G.6
Budman, D.R.7
Henderson, I.C.8
Barcos, M.9
Hayes, D.10
-
4
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 248-254.
-
(1976)
Analytical Biochemistry
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
5
-
-
0035971181
-
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
-
Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S & Nakshatri H 2001 Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. Journal of Biological Chemistry 276 9817-9824.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 9817-9824
-
-
Campbell, R.A.1
Bhat-Nakshatri, P.2
Patel, N.M.3
Constantinidou, D.4
Ali, S.5
Nakshatri, H.6
-
6
-
-
0026610881
-
Humanization of an anti-p185HER2 antibody for human cancer therapy
-
Carter P, Presta L, Gorman CM, Ridgway JB, Henner D, Wong WL, Rowland AM, Kotts C, Carver ME & Shepard HM 1992 Humanization of an anti-p185HER2 antibody for human cancer therapy. PNAS 89 4285-4289.
-
(1992)
PNAS
, vol.89
, pp. 4285-4289
-
-
Carter, P.1
Presta, L.2
Gorman, C.M.3
Ridgway, J.B.4
Henner, D.5
Wong, W.L.6
Rowland, A.M.7
Kotts, C.8
Carver, M.E.9
Shepard, H.M.10
-
7
-
-
18844365440
-
Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors
-
Chan CT, Metz MZ & Kane SE 2005 Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors. Breast Cancer Research and Treatment 91 187-201.
-
(2005)
Breast Cancer Research and Treatment
, vol.91
, pp. 187-201
-
-
Chan, C.T.1
Metz, M.Z.2
Kane, S.E.3
-
8
-
-
0036633164
-
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
-
Clark AS, West K, Streicher S & Dennis PA 2002 Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Molecular Cancer Therapeutics 1 707-717.
-
(2002)
Molecular Cancer Therapeutics
, vol.1
, pp. 707-717
-
-
Clark, A.S.1
West, K.2
Streicher, S.3
Dennis, P.A.4
-
9
-
-
0034754665
-
Interaction between Herceptin and taxanes
-
Dieras V, Beuzeboc P, Laurence V, Pierga JY & Pouillart P 2001 Interaction between Herceptin and taxanes. Oncology 61 (Suppl 2) 43-49.
-
(2001)
Oncology
, vol.61
, Issue.SUPPL. 2
, pp. 43-49
-
-
Dieras, V.1
Beuzeboc, P.2
Laurence, V.3
Pierga, J.Y.4
Pouillart, P.5
-
10
-
-
27644476924
-
Biological characteristics of the pure antiestrogen fulvestrant: Overcoming endocrine resistance
-
Dowsett M, Nicholson RI & Pietras RJ 2005 Biological characteristics of the pure antiestrogen fulvestrant: overcoming endocrine resistance. Breast Cancer Research and Treatment 93 (Suppl 1) S11-S18.
-
(2005)
Breast Cancer Research and Treatment
, vol.93
, Issue.SUPPL. 1
-
-
Dowsett, M.1
Nicholson, R.I.2
Pietras, R.J.3
-
11
-
-
35148859334
-
Trastuzumab-resistant HER2-driven breast cancer cells are sensitive to epigallocatechin-3 gallate
-
Eddy SF, Kane SE & Sonenshein GE 2007 Trastuzumab-resistant HER2-driven breast cancer cells are sensitive to epigallocatechin-3 gallate. Cancer Research 67 9018-9023.
-
(2007)
Cancer Research
, vol.67
, pp. 9018-9023
-
-
Eddy, S.F.1
Kane, S.E.2
Sonenshein, G.E.3
-
12
-
-
0028886694
-
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
-
Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, Sasaki H, Masushige S, Gotoh Y, Nishida E, Kawashima H et al. 1995 Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270 1491-1494.
-
(1995)
Science
, vol.270
, pp. 1491-1494
-
-
Kato, S.1
Endoh, H.2
Masuhiro, Y.3
Kitamoto, T.4
Uchiyama, S.5
Sasaki, H.6
Masushige, S.7
Gotoh, Y.8
Nishida, E.9
Kawashima, H.10
-
13
-
-
0034667395
-
Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells
-
Kurokawa H, Lenferink AE, Simpson JF, Pisacane PI, Sliwkowski MX, Forbes JT & Arteaga CL 2000 Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells. Cancer Research 60 5887-5894.
-
(2000)
Cancer Research
, vol.60
, pp. 5887-5894
-
-
Kurokawa, H.1
Lenferink, A.E.2
Simpson, J.F.3
Pisacane, P.I.4
Sliwkowski, M.X.5
Forbes, J.T.6
Arteaga, C.L.7
-
14
-
-
0034662968
-
Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu+MMTV/TGF-α bigenic mite
-
Lenferink AE, Simpson JF, Shawver LK, Coffey RJ, Forbes JT & Arteaga CL 2000 Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu+MMTV/TGF-α bigenic mite. PNAS 97 9609-9614.
-
(2000)
PNAS
, vol.97
, pp. 9609-9614
-
-
Lenferink, A.E.1
Simpson, J.F.2
Shawver, L.K.3
Coffey, R.J.4
Forbes, J.T.5
Arteaga, C.L.6
-
15
-
-
34250687888
-
Functional analysis on the 5′-flanking region of human FXR gene in HepG2 cells
-
Lou G, Li Y, Chen B, Chen M, Chen J, Liao R, Zhang Y, Wang Y & Zhou D 2007 Functional analysis on the 5′-flanking region of human FXR gene in HepG2 cells. Gene 396 358-368.
-
(2007)
Gene
, vol.396
, pp. 358-368
-
-
Lou, G.1
Li, Y.2
Chen, B.3
Chen, M.4
Chen, J.5
Liao, R.6
Zhang, Y.7
Wang, Y.8
Zhou, D.9
-
16
-
-
0035915421
-
Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
-
Lu Y, Zi X, Zhao Y, Mascarenhas D & Pollak M 2001 Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). Journal of the National Cancer Institute 93 1852-1857.
-
(2001)
Journal of the National Cancer Institute
, vol.93
, pp. 1852-1857
-
-
Lu, Y.1
Zi, X.2
Zhao, Y.3
Mascarenhas, D.4
Pollak, M.5
-
17
-
-
0035476803
-
The tyrosine kinase inhibitor ZD1839 ('Iressa') inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells
-
Moasser MM, Basso A, Averbuch SD & Rosen N 2001 The tyrosine kinase inhibitor ZD1839 ('Iressa') inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells. Cancer Research 61 7184-7188.
-
(2001)
Cancer Research
, vol.61
, pp. 7184-7188
-
-
Moasser, M.M.1
Basso, A.2
Averbuch, S.D.3
Rosen, N.4
-
18
-
-
33646712747
-
Mechanisms of disease: Understanding resistance to HER2-targeted therapy in human breast cancer
-
Nahta R, Yu D, Hung MC, Hortobagyi GN & Esteva FJ 2006 Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer. Nature Clinical Practice and Oncology 3 269-280.
-
(2006)
Nature Clinical Practice and Oncology
, vol.3
, pp. 269-280
-
-
Nahta, R.1
Yu, D.2
Hung, M.C.3
Hortobagyi, G.N.4
Esteva, F.J.5
-
19
-
-
0028997307
-
HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells
-
Pietras RJ, Arboleda J, Reese DM, Wongvipat N, Pegram MD, Ramos L, Gorman CM, Parker MG, Sliwkowski MX & Slamon DJ 1995 HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells. Oncogene 10 2435-2446.
-
(1995)
Oncogene
, vol.10
, pp. 2435-2446
-
-
Pietras, R.J.1
Arboleda, J.2
Reese, D.M.3
Wongvipat, N.4
Pegram, M.D.5
Ramos, L.6
Gorman, C.M.7
Parker, M.G.8
Sliwkowski, M.X.9
Slamon, D.J.10
-
20
-
-
0037142184
-
Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance
-
Price-Schiavi SA, Jepson S, Li P, Arango M, Rudland PS, Yee L & Carraway KL 2002 Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance. International Journal of Cancer 99 783-791.
-
(2002)
International Journal of Cancer
, vol.99
, pp. 783-791
-
-
Price-Schiavi, S.A.1
Jepson, S.2
Li, P.3
Arango, M.4
Rudland, P.S.5
Yee, L.6
Carraway, K.L.7
-
21
-
-
9144256614
-
Cross-talk between estrogen receptor and growth factor pathways as a molecular target for overcoming endocrine resistance
-
Schiff R, Massarweh SA, Shou J, Bharwani L, Mohsin SK & Osborne CK 2004 Cross-talk between estrogen receptor and growth factor pathways as a molecular target for overcoming endocrine resistance. Clinical Cancer Research 10 331S-336S.
-
(2004)
Clinical Cancer Research
, vol.10
-
-
Schiff, R.1
Massarweh, S.A.2
Shou, J.3
Bharwani, L.4
Mohsin, S.K.5
Osborne, C.K.6
-
22
-
-
2942652871
-
Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer
-
Shou J, Massarweh S, Osborne CK, Wakeling AE, Ali S, Weiss H & Schiff R 2004 Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer. Journal of the National Cancer Institute 96 926-935.
-
(2004)
Journal of the National Cancer Institute
, vol.96
, pp. 926-935
-
-
Shou, J.1
Massarweh, S.2
Osborne, C.K.3
Wakeling, A.E.4
Ali, S.5
Weiss, H.6
Schiff, R.7
-
23
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, Keith DE, Levin WJ, Stuart SG, Udove J, Ullrich A et al. 1989 Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244 707-712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
-
24
-
-
0030946198
-
Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen
-
Smith CL, Nawaz Z & O'Malley BW 1997 Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen. Molecular Endocrinology 11 657-666.
-
(1997)
Molecular Endocrinology
, vol.11
, pp. 657-666
-
-
Smith, C.L.1
Nawaz, Z.2
O'Malley, B.W.3
-
25
-
-
0036137605
-
Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation
-
Song RX, McPherson RA, Adam L, Bao Y, Shupnik M, Kumar R & Santen RJ 2002 Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation. Molecular Endocrinology 16 116-127.
-
(2002)
Molecular Endocrinology
, vol.16
, pp. 116-127
-
-
Song, R.X.1
McPherson, R.A.2
Adam, L.3
Bao, Y.4
Shupnik, M.5
Kumar, R.6
Santen, R.J.7
-
26
-
-
0035881568
-
Phosphatidylinositol-3-OH kinase (PI3K)/ AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERα) via interaction between ERα and PI3K
-
Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, Lu YY, Shelley SA, Nicosia SV & Cheng JQ 2001 Phosphatidylinositol-3-OH kinase (PI3K)/ AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERα) via interaction between ERα and PI3K. Cancer Research 61 5985-5991.
-
(2001)
Cancer Research
, vol.61
, pp. 5985-5991
-
-
Sun, M.1
Paciga, J.E.2
Feldman, R.I.3
Yuan, Z.4
Coppola, D.5
Lu, Y.Y.6
Shelley, S.A.7
Nicosia, S.V.8
Cheng, J.Q.9
-
27
-
-
0029666144
-
Involvement of heregulin-beta2 in the acquisition of the hormone-independent phenotype of breast cancer cells
-
Tang CK, Perez C, Grunt T, Waibel C, Cho C & Lupu R 1996 Involvement of heregulin-beta2 in the acquisition of the hormone-independent phenotype of breast cancer cells. Cancer Research 56 3350-3358.
-
(1996)
Cancer Research
, vol.56
, pp. 3350-3358
-
-
Tang, C.K.1
Perez, C.2
Grunt, T.3
Waibel, C.4
Cho, C.5
Lupu, R.6
-
28
-
-
33751168744
-
Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor
-
Tseng PH, Wang YC, Weng SC, Wang JR, Chen CS, Brueggemeier RW, Shapiro CL, Chen CY, Dunn SE, Pollak M et al. 2006 Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor. Molecular Pharmacology 70 1534-1541.
-
(2006)
Molecular Pharmacology
, vol.70
, pp. 1534-1541
-
-
Tseng, P.H.1
Wang, Y.C.2
Weng, S.C.3
Wang, J.R.4
Chen, C.S.5
Brueggemeier, R.W.6
Shapiro, C.L.7
Chen, C.Y.8
Dunn, S.E.9
Pollak, M.10
-
29
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel CL, Cobleigh MA, Tripathy D, Gutheil JC, Harris LN, Fehrenbacher L, Slamon DJ, Murphy M, Novotny WF, Burchmore M et al. 2002 Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. Journal of Clinical Oncology 20 719-726.
-
(2002)
Journal of Clinical Oncology
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
-
30
-
-
24644453938
-
In vitro and in vivo effects of combination of trastuzumab (Herceptin) and Tamoxifen in breast cancer
-
Wang CX, Koay DC, Edwards A, Lu Z, Mor G, Ocal IT & Digiovanna MP 2005 In vitro and in vivo effects of combination of trastuzumab (Herceptin) and Tamoxifen in breast cancer. Breast Cancer Research and Treatment 92 251-263.
-
(2005)
Breast Cancer Research and Treatment
, vol.92
, pp. 251-263
-
-
Wang, C.X.1
Koay, D.C.2
Edwards, A.3
Lu, Z.4
Mor, G.5
Ocal, I.T.6
Digiovanna, M.P.7
-
31
-
-
0037069418
-
Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade
-
Wong CW, McNally C, Nickbarg E, Komm BS & Cheskis BJ 2002 Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade. PNAS 99 14783-14788.
-
(2002)
PNAS
, vol.99
, pp. 14783-14788
-
-
Wong, C.W.1
McNally, C.2
Nickbarg, E.3
Komm, B.S.4
Cheskis, B.J.5
-
32
-
-
0037099532
-
Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action
-
Yakes FM, Chinratanalab W, Ritter CA, King W, Seelig S & Arteaga CL 2002 Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action. Cancer Research 62 4132-4141.
-
(2002)
Cancer Research
, vol.62
, pp. 4132-4141
-
-
Yakes, F.M.1
Chinratanalab, W.2
Ritter, C.A.3
King, W.4
Seelig, S.5
Arteaga, C.L.6
-
33
-
-
2542620761
-
Human epidermal growth factor receptor 2 status modulates subcellular localization of and interaction with estrogen receptor alpha in breast cancer cells
-
Yang Z, Barnes CJ & Kumar R 2004 Human epidermal growth factor receptor 2 status modulates subcellular localization of and interaction with estrogen receptor alpha in breast cancer cells. Clinical Cancer Research 10 3621-3628.
-
(2004)
Clinical Cancer Research
, vol.10
, pp. 3621-3628
-
-
Yang, Z.1
Barnes, C.J.2
Kumar, R.3
-
34
-
-
34247242607
-
Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
-
Zhou Y, Yau C, Gray JW, Chew K, Dairkee SH, Moore DH, Eppenberger U, Eppenberger-Castori S & Benz CC 2007 Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer. BMC Cancer 7 59.
-
(2007)
BMC Cancer
, vol.7
, pp. 59
-
-
Zhou, Y.1
Yau, C.2
Gray, J.W.3
Chew, K.4
Dairkee, S.H.5
Moore, D.H.6
Eppenberger, U.7
Eppenberger-Castori, S.8
Benz, C.C.9
|