Multistability as intrinsic property of a single cardiac cell: A simulation study

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn , Issue , 2007, Pages 927-930

  Surovyatkina, Elena ^a   Egorchenkov, Roman ^a   Ivanov, Guennady ^b  

^a Russian Academy of Sciences   (Russian Federation)

^b I M SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLOGY; COMPUTATIONAL METHODS; ELECTROCARDIOGRAPHY; MATHEMATICAL MODELS;

COMPLEX ENTRAINMENT MODES; MULTISTABILITY ZONE; TRANSMEMBRANE POTENTIAL CURVE;

CELLS;

ACTION POTENTIAL; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOLOGICAL RHYTHM; COMPUTER SIMULATION; HEART MUSCLE CELL; HEART MUSCLE CONDUCTION SYSTEM; HUMAN; PHYSIOLOGY;

ACTION POTENTIALS; ANIMALS; BIOLOGICAL CLOCKS; COMPUTER SIMULATION; HEART CONDUCTION SYSTEM; HUMANS; MODELS, CARDIOVASCULAR; MYOCYTES, CARDIAC;

EID: 57649202939     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/IEMBS.2007.4352443     Document Type: Conference Paper

References (10)

1. M. R. Guevara, F. Alonso, D. Jeandupeux, and A.C.G. van Ginneken, "Alternans in periodically stimulated isolated ventricular myocytes: Experiment and model," in Cell to Cell Signalling: From Experiments to Theoretical Models, edited by A. Goldbeter (Harcourt Brace Jovanovich, London, 1989), pp. 551-563.
2. A. R. Yehia, D. Jeandupeux, F. Alonso, and M. R.Guevara, "Hysteresis and Bistability in the Direct Transition from 1:1 to 2:2 Rhythm in Periodically Driven Single Ventricular Cells", Chaos, vol. 9, no. 4, 1999, pp. 916-931.
3. M. R. Guevara, G.Ward, A. Shrier, and L. Glass, "Electrical alternans and period-doubling bifurcations," Computers in Cardiology (IEEE Comp. Soc. Press, Silver Spring, MD, 1984), pp. 167-170.
4. G.M.Hall, S. Bahar, and D.J.Gauthier, "Prevalence of ratedependent behaviors in cardiac muscle," Phys. Rev. Lett., vol 82, 1999, pp. 2995-2998.
5. G. J. Anderson, K. Greenspan, C. Fisch, "Electrophysiologic studies on Wenckebach structures below the atrioventricular junction", Am. J. Cardiol., vol. 30, 1972, pp. 232-236.
6. R. El-Sherif, R.R. Hope, B.J. Scherlag, R. Lazara, "Re-entrant ventricular arrhythmias in the late myocardial infarction period", Circulation, vol. 55, 1977, pp. 702-/718.
7. Ch. Zemlin, E. Storch, H. Herzel, "Alternans and 2:1 rhythms in an ionic model of heart cells", BioSystems, vol. 66, pp. 1-10, 2002.
8. CH. Luo, Y. Rudy, "A model of the ventricular cardiac action potential. Depolarization, repolarization and their interaction", Circulation, vol. 68, 1991, pp. 1501-1526.
9. Zh. Qu, "Dynamical effects of diffusive cell coupling on cardiac excitation and propagation: a simulatopn study", Am. J. Physiol. Heart Circ. Physiol. 287, 2004, H2803-H2812.
10. J. I. Goldhaber, L. H. Xie, T. Duong, C. Motter, K. Khuu, and J. N. Weiss, "Action potential duration restitution and alternans in rabbit ventricular myocytes: the key role of intracellular calcium cycling", Circ. Res., vol. 96, 2005, pp. 459-4-66.