Quantification of uncertainty of peptide retention time predictions from a sequence-based model in LC-MS/MS proteomics experiments

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn , Issue , 2007, Pages 1221-1224

  Yanofsky, Corey M ^a   Kearney, Robert E ^a   Lesimple, Souad ^a   Bergeron, John J M ^a   Boismenu, Daniel ^a   Carrillo, Brian ^a   Bell, Alexander W ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PARAMETER ESTIMATION; PROBLEM SOLVING; UNCERTAINTY ANALYSIS;

PROTEOMICS; QUANTIFICATION;

PEPTIDES;

PEPTIDE; PROTEOME;

ALGORITHM; AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; EVALUATION STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR GENETICS; PEPTIDE MAPPING; PROTEOMICS; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS;

ALGORITHMS; AMINO ACID SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PEPTIDES; PROTEOME; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, PROTEIN;

EID: 57649171444     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/IEMBS.2007.4352517     Document Type: Conference Paper

References (5)

1. D. F. Hochstrasser, J.-C. Sanchez, R. D. Appel, " Proteomics and its trends facing nature's complexity," Proteomics, vol. 2, iss. 7, pp. 807-812, 2002.
2. P. A. Hanes, Jr., J. R. Yates, III, ""Proteome profiling - pitfalls, and progress," Yeast Comput. Fund. Genet, vol. 17, iss. 2, pp. 81-87, 2000.
3. C. M. Yanofsky, A. W. Bell, S. Lesimple, D. Boismenu, B. Carrillo, J. J. M. Bergeron, R. E. Kearney, "A Statistical Model for Alignment of Peptide Retention Times from Liquid Chromatography-Mass Spectrometry Analyses," unpublished.
4. O. V. Krokhin, "Sequence-Specific Retention Calculator. Algorithm for Peptide Retention Prediction in Ion-Pair RP-HPLC: Application to 300- and 100-Å Pore Size C18 Sorbents," Anal. Chem., vol. 78, iss. 22, pp. 7785-7795, 2006.
5. J. S. D. Zimmer, M. E. Monroe, W.-J. Qian, R. D. Smith, "Advances in proteomics data analysis and display using an accurate mass and time tag approach," Mass Spec. Rev., vol. 25, pp. 450-482, 2006.