Human voltage-dependent anion selective channel 1 is a target antigen for antiglomerular endothelial cell antibody in mixed connective tissue disease

Modern Rheumatology

Volumn 18, Issue 6, 2008, Pages 570-577

  Kikuchi, Tamami ^a   Yoshida, Yutaka ^a   Morioka, Tetsuo ^a   Gejyo, Fumitake ^a   Oite, Takashi ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

Antiendothelial cell antibody; HGEC; MCTD; Proteomics; VDAC 1

Indexed keywords

CELL ANTIGEN; ENDOTHELIAL CELL ANTIBODY; ENDOTHELIAL CELL ANTIGEN; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 1;

ADULT; ANTIBODY SPECIFICITY; ANTIGEN DETECTION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GLOMERULUS; HUMAN; IMMUNOBLOTTING; ISOELECTRIC POINT; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEDICAL RESEARCH; MIXED CONNECTIVE TISSUE DISEASE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN TARGETING; PROTEOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

AUTOANTIBODIES; AUTOANTIGENS; CELLS, CULTURED; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOTHELIUM, VASCULAR; GLOMERULAR MESANGIUM; HUMANS; KIDNEY GLOMERULUS; MIXED CONNECTIVE TISSUE DISEASE; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; VOLTAGE-DEPENDENT ANION CHANNEL 1;

EID: 57649165410     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.1007/s10165-008-0094-4     Document Type: Article

References (22)

1. Sharp GC, Irvin WS, Tan EM, Gould RG, Holman HR. Mixed connective tissue disease, an apparent distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med. 1972;52:138-59.
2. Hosoda Y, Suzuki Y, Takano M, Tojo T, Homma M. Mixed connective tissue disease with pulmonary hypertension: A clinical and pathological study. J Rheumatol. 1987;14(4):826-30.
3. Filep JG, Bodolay E, Sipka S, Gyimesi E, Csipo I, Szegedi G. Plasma endothelin correlates with andiendothelial antibodies in patients with mixed connective tissue disease. Circulation. 1995;92:2968-74.
4. Bodolay E, Csipo I, Gal I, Sipka S, Gyimesi E, Szekanecz Z, et al. Anti-endothelial cell antibodies in mixed connective tissue disease: frequency and association with clinical symptoms. Clin Exp Rheumatol. 2004;22(4):409-15.
5. Kasukawa R, Tojo T, Miyawaki S, Yoshida H, Tanimoto K, Nobunaga M, et al. Preliminary diagnostic criteria for mixed connective tissue disease. In: Kasukawa R, Sharp GC, editors. Mixed connective tissue disease and antinuclear antibodies. Elsevier: Amsterdam; 1987. p. 41-7.
6. Kuroda T, Matsuyama K, Nakatsue T, Murakami S, Hasegawa H, Nakayama H, et al. A case of mixed connective tissue disease complicated with thrombotic thrombocytopenic purpura. Clin Rheumatol. 2007;26(1):101-4.
7. Harada T, Batsford S, Morioka T, Jian Y, Arakawa M, Gejyo F, et al. Establishment of immortalized human glomerular endothelial cell lines and their application. Exp Nephrol. 2005;99:e38-45.
8. Morita T, Oite T, Kihara I, Yamamoto T, Hara M, Naka A, et al. Culture of isolated glomeruli from normal and nephritic rabbits. I. Characterization of out growing cells. Acta Pathol Jpn. 1980;30:917-26.
9. Striker GE, Killen PD, Farin FM. Human glomerular cells in vitro isolation and characterization. Transplant Proc. 1980;12:88-99.
10. Saito K, Shimizu F, Sato T, Oite T. Modulation of human mesangial cell behaviour by extracellular matrix components-the possible role of interstitial type III collagen. Clin Exp Immunol. 1993;91:510-5.
11. Murakami S, Morioka T, Nakagawa Y, Suzuki Y, Arakawa M, Oite T. Expression of adhesion molecules by cultured human glomerular endothelial cells in response to cytokines: Comparison to human umbilical vein and dermal microvascular endothelial cells. Microvasc Res. 2001;62:383-91.
12. Praprotnik S, Blank M, Meroni PL, Rozman B, Eldor A, Shoenfeld Y. Classification of anti-endothelial cell antibodies into antibodies against microvascular and macrovascular endothelial cells. Arthritis Rheum. 2001;44(7):1484-94 (review).
13. Youinou P, Dantec CL, Bendaoud B, Renaudineau Y, Pers JO, Jamin C. Endothelium, a target for immune-mediated assault in connective tissue disease. Autoimmun Rev. 2006;5:222-8.
14. Heurkens AH, Hiemstra PS, Lafeber GJ, Daha MR, Breedveld FC. Anti-endothelial cell antibodies in patients with rheumatoid arthritis complicated by vasculitis. Clin Exp Immunol. 1989;78(1):7-12.
15. Burdt MA, Hoffman RW, Deutscher SL, Wang GS, Johnson JC, Sharp GC. Long-term outcome in mixed connective tissue disease. Longitudinal clinical and serologic findings. Arthritis Rheum. 1999;42(5):899-909.
16. Kasukawa R, Nishimaki T, Takagi T, Miyawaki S, Yokohari R, Tsunematsu T. Pulmonary hypertension in connective tissue disease. Clinical analysis of sixty patients in multi-institutional study. Clin Rheumatol. 1990;9(1):56-62.
17. de Holanda Mafaldo Diogenes A, Bonfa E, Fuller R, Correia Caleiro MT. Capillaroscopy is a dynamic process in mixed connective tissue disease. Lupus. 2007;16:254-8.
18. Watanabe H, Kaise S, Takeda I, Matsuzaki H, Kobayashi H, Nishimaki T. Anti-endothelial cell antibodies in the sera of patients with mixed connective tissue disease-the clinical significance. Fukushima J Med Sci. 1997;43(1):13-28.
19. Bodolay E, Bojan F, Szegedi G, Stenszky V, Farid NR. Cytotoxic endothelial cell antibodies in mixed connective tissue disease. Immuno Lett. 1989;20(2):163-7.
20. De Pinto V, Messina A, Accar di R, Aiello R, Guarino F, Tomasello MF, et al. New functions of an old protein: The eukaryotic porin or voltage dependent anion selective channel (VDAC). Ital J Biochem. 2003;52(1):17-24 (review).
21. Lawen A, Ly JD, Lane DJ, Zarschler K, Messina A, De Pinto V. Voltage-dependent anion-selective channel 1 (VDAC1)-a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane. Int J Biochem Cell Biol. 2005;37(2):277-82 (review).
22. Baker MA, Lane DJ, Ly JD, De Pinto V, Lawen A. VDAC1 is a transplasma membrane NADH-ferricyanide reductase. J Biol Chem. 2004;279(6):4811-9.