Successful treatment of ligneous gingivitis with warfarin

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology

Volumn 107, Issue 1, 2009, Pages 77-80

  Fine, Gregg ^a   Bauer, Kenneth ^b   Al Mohaya, Maha ^c   Woo, Sook Bin ^d  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b Division of Hematology and Oncology   (United States)

^c Prince Sultan Military Medical City   (Saudi Arabia)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; PLASMINOGEN; WARFARIN;

ARTICLE; BLOOD CLOTTING DISORDER; CASE REPORT; FEMALE; GINGIVITIS; HOMOZYGOTE; HUMAN; MIDDLE AGED; UTERINE CERVICITIS;

ANTICOAGULANTS; COAGULATION PROTEIN DISORDERS; FEMALE; GINGIVITIS; HOMOZYGOTE; HUMANS; MIDDLE AGED; PLASMINOGEN; UTERINE CERVICITIS; WARFARIN;

EID: 57649149260     PISSN: 10792104     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tripleo.2008.08.007     Document Type: Article

References (16)

1. Gokbuget A.Y., Mutulu S., Scully, Efeoglu A., Porter S.R., Speight P., et al. Amyloidaceous ulcerated gingival hyperplasia: a newly descreibed entity related to ligneous conjunctivitis. J Oral Pathol Med 26 (1997) 100-104
2. Gunhan O., Gunhan M., Berker E., Gurgan C.A., and Yildrum H. Destructive membranous periodontal disease (ligneous periodontitis). J Periodontol 70 (1999) 919-925
3. Schuster V., Zeitler P., Seregard S., Ozcelik U., Anadol D., Luchtman-Jones L., et al. Homozygous and compound-heterozygous type I plasminogen deficiency is a common cause of ligneous conjunctivitis. Thromb Haemost 85 (2001) 1004-1010
4. Teresa Sartori M., Saggiorato G., Pellati D., Casonato A., Spiezia L., Pontara E., et al. Contraceptive pills induce an improvement in congenital hypoplasminogenemia in two unrelated patients with ligneous conjunctivitis. Thromb Haemost 90 (2003) 86-91
5. Kurtulus I., Gokbuget A., Efeoglu A., Cintan S., Tefs K., Schuster V., et al. Hypoplasminogenemia with ligneous periodontitis: a failed local therapeutic approach. J Periodontol 78 (2007) 1164-1175
6. Pantanowitz L., Bauer K., Tefs K., Schuster V., Balogh K., Pilch B., et al. Ligneous (pseudomembranous) inflammation involving the female genital tract associated with type-1 plasminogen deficiency. Int J Gynecol Pathol 23 (2004) 292-295
7. Bouisson M. Opthalmie sur-aigue avec formation de pseudomembranes a la surface de la conjonctive. Ann Oculist 17 (1847) 100-104
8. Mingers A.M. Homozygous type I plasminogen deficiency. Semin Thromb Hemost 23 (1997) 259-263
9. Tefs K., Gueorguieva M., Klammt J., Allen C., Aktas D., Anlar F., et al. Molecular and clinical spectrum of type I plasminogen deficiency: a series of 50 patients. Blood 108 (2006) 3021-3026
10. Schuster V., Seidenspinner S., Zeitler P., Escher C., Pleyer U., Bernauer W., et al. Compound-heterozygous mutations in the plasminogen gene predispose to the development of ligneous conjunctivitis. Blood 93; (1999) 3457-3466
11. Schuster V., and Hugle B. and Tefs K. Plasminogen deficiency. J Thromb Haemost 5 (2007) 2315
12. Naudi K.B., Hunter K.D., MacDonald D.G., and Felix D.H. Ligneous alveolar gingivitis in the absence of plasminogen deficiency. J Oral Pathol Med 25 (2006) 636-638
13. Diamond J.P., Chandna A., Williams C., Easty D.L., Scully C., Eveson J., and Richards A. Tranexamic acid-associated ligneous conjunctivitis with gingival and peritoneal lesions. Br. J Ophthalmol 75 (1991) 753-754
14. Kluft C. The fibrinolytic system and thrombotic tendency. Pathophysiol Thromb Haemost 2003/ 33 (2004) 425-429
15. Schott D., Dempfle C.E., Beck P., Liermann A., Nohr-Pennert A., Goldner M., et al. Therapy with a purified plasminogen concentrate in an infant with ligneous conjunctivitis and homozygous plasminogen Deficiency. N Engl J Med 339 (1998) 1679-1686
16. Heidemann D., Williams G.A., Hartzer M., Ohanian A., and Citron M.E. Treatment of ligneous conjunctivitis with topical plasmin and topical plasminogen. Cornea 22 (2003) 760-762