Nadir CD4 T-cell counts continue to influence interferon-γ responses in HIV patients who began antiretroviral treatment with advanced immunodeficiency

Journal of Acquired Immune Deficiency Syndromes

Volumn 49, Issue 4, 2008, Pages 462-464

  Price, Patricia ^a,b   Fernandez, Sonia ^b   Tan, Dino B A ^b   James, Ian R ^c   Keane, Niamh M ^b,c   French, Martyn A ^a,b  

^a ROYAL PERTH HOSPITAL   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c MURDOCH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; CANDIDA; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CYTOMEGALOVIRUS; DISEASE SEVERITY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; LETTER; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; TREATMENT RESPONSE;

ADULT; ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; HIV INFECTIONS; HUMANS; INTERFERON-GAMMA;

EID: 57649138670     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e31817e637e     Document Type: Letter

References (8)

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3. + T cell nadir is an independent predictor of lower HIV-specific immune responses in chronically HIV-1-infected subjects receiving highly active antiretroviral therapy. J Infect Dis. 2006;194:661-665.
4. Burgess K, Price P, James IR, et al. Interferon-gamma responses to Candida recover slowly or remain low in immunodeficient HIV patients responding to ART. J Clin Immunol. 2006;26:160-169
5. + T-cell activation and senescence but not with lower effector memory T-cell function. Clin Immunol. 2006;120:163-170.
6. + T-cell responses in HIV patients responding to ART may be limited by low proportions of plasmacytoid dendritic cells rather than poor production of accessory cytokines. Clin Immunol. 2008; [Epub ahead of print].
7. Price P, Keane NM, Lee S, et al. A T2 cytokine environment may not limit T1 responses in human immunodeficiency virus patients with a favourable response to anti-retroviral therapy. Immunology. 2006;119:74-82.
8. Price P, Witt C, Santis DD, et al. Killer immunoglobulin-like receptor genotype may distinguish immunodeficient HIV-infected patients resistant to immune restoration diseases associated with herpes virus infections. J Acquir Immune Defic Syndr. 2007;45:359-361.