Urinary Mutagenicity in Chemical Laboratory Workers Exposed to Solvents

Journal of Occupational Health

Volumn 50, Issue 5, 2008, Pages 415-422

  Varella, Soraya D ^a   Rampazo, Raquel A ^a   Varanda, Eliana A ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Genotoxic exposure; Reversion assay; Salmonella; Solvents; Urine mutagenicity

Indexed keywords

SALMONELLA; SALMONELLA TYPHIMURIUM;

EID: 57649137254     PISSN: 13419145     EISSN: 13489585     Source Type: Journal    
DOI: 10.1539/joh.L7151     Document Type: Article

References (43)

1. Phillips BJ and Jenkinson P: Is ethanol genotoxic? A review of the published data. Mutagenesis 16, 91-101 (2001).
2. Joo WA, Donggeun S, Lee DY, Lee E and Kim CW: Proteomic analysis of plasma proteins of workers exposed to benzene. Mutat Res 558, 35-44 (2004).
3. Snyder R, Lee EW, Kocsis JJ and Witmer CM: Bone marrow depressant and leukemogenic actions of benzene. Life Sci 21, 1709-1722 (1977).
4. Akson M: Benzene as leukemogenic and carcinogenic agent. Am J Ind Med 8, 9-20 (1985).
5. Andrews LS and Snyder R: Toxic effects of solvents and vapors. In: Amdur MO, Doull J, Klaassen CD, eds.Toxicology-The Basic Science of Poisons. New York: Pergamon Press, 1991: 681-722.
6. Fechner G, Ortmann A and Köhler H: Fatal intoxication due to excessive dichloromethane inhalation. Forensic Science International 22, 69-72 (2001).
7. Maninni P, Andreoli R and Niessen WMA: Liquid chromatography-mass spectrometry in occupational toxicology: a novel approach to the study of biotransformation of industrial chemicals. J Chromatography A 1058, 21-37 (2004).
8. Neubert D, Gericke C, Hanke B, Beckmann G, Baltes MM, Kuhl K-P, Bochert G, Hartmann J and Toluene Field Study Group: Multicenter field trial on possible health effects of toluene II. Cross sectional evaluation of acute low-level exposure. Toxicology 168, 159-183 (2001).
9. DeFlora S, Zanacchi P, Camoirano A, Bennocelli C and Badolati GS: Genotoxic activity of 135 compounds in the Ames revertion test and in bacterial DNA-repair test. Mutat Res 133, 161-198 (1984).
10. Andre V, Lebailly P, Deslands E, Henry-Amar M and Gauduchon P: Biomonitoring of urine mutagenicity with the Ames test: improvement of the extraction/concentration method. Mutat Res 520, 199-205 (2002).
11. DeMarine DM, Brooks LR, Bhatanagar VK, Hayes RB, Eischein BT, Shelton ML, Zenser TV, Talaska G, Kashyap R, Parikh DJ, Lakshmi V, Hsu F, Davis BB, Jarger M and Rothman N: Urinary mutagenicity as a biomarker in workers exposed to benzidine: correlation with urinary metabolites and urothelial DNA adducts. Carcinogenesis 18, 981-988 (1997).
12. Yamasaki E and Ames BN: Concentration of mutagens from urine by adsorption with the nonpolar resin XAD-2: cigarrete smokers have mutagenic urine. Proc Natl Acad Sci 74, 3555-3559 (1977).
13. Falck P, Gröhn M, Sorsa H, Vainio E, Heinonen K and Holsti LR: Mutagenicity in urine of nurses handling cytostatic drugs. Lancet 1, 1250-1251 (1979).
14. Doolittle DJ, Rahn CA, Burger JT, Lee CK, Reed B, Riccio E, Howard G, Passananti GT, Vesell ES and Hayes AW: Effect of cooking methods on the mutagenicity of food and on urinary mutagenicity of human consumers. Food Chem Toxicol 27, 657-666 (1989).
15. Falck K, Sorsa M, Vainio H and Kilpikari I: Mutagenicity in urine of workers in rubber industry. Mutat Res 79, 445-452 (1980).
16. Sinues B, Perez J, Bernal ML, Saenz MA, Lanuza J and Bartolome M: Urinary mutagenicity and N-acetylation phenotype in textile industry workers exposed to arylamines. Cancer Res 52, 4885-4889 (1992).
17. Dolara P, Mazzoli S, Rosi D, Buiatti E, Baccetti S, Turchi A and Vannucci V: Exposure to carcinogenic chemicals and smoking increases urinary excretion of mutagens in humans. Toxicol Environ Health 8, 95-103 (1981).
18. Maron DM and Ames BN: Revised methods for the Salmonella mutagenicity test. Mutat Res 113, 173-225 (1983).
19. Watanabe M, Ishidate MJ and Nohemi T: Sensitive method for detection of mutagenic nitroarenes and aromatic amines: new derivates of Salmonella typhimurium tester strains possessing elevated O-acetiltransferase levels. Mutat Res 234, 337-348 (1990).
20. Einistö P, Noehmi T and Ishidate M: Sentivivity of Salmonella typhimurium YG1024 urine mutagenicity caused by cigarrete smoking. Mutat Res 245, 87-92 (1990).
21. Varella SD, Pozetti GL, Vilegas W and Varanda EA: Mutagenic activity of sweepings and pigments of a household-wax factory assayed with Salmonella typhimurium. Food Chem Toxicol 42, 2029-2035 (2004).
22. Marques RCP, Medeiros SRB, Dias CS, Barbosa-Filho JM and Agnez-Lima LF: Evaluation of the mutagenic potential of yangambin and of the hydroalcoholic extract of Ocotea duckei by the Ames Test. Mutat Res 536, 117-120 (2003).
23. Cavalcanti AAM, Rubensam G, Picada JN, Silva EG, Moreira JCF and Henriques JAP: Mutagenicity, antioxidant potential, and antimutagenic activity against hydrogen peroxide of cashew (Anacardium occidentale) apple juice and cajuína. Environ and Mol Mutagen 41, 360-369 (2003).
24. Kutlu M, Aydogan G, Susuz F and Özata A: The Salmonella mutagenicity of water and sediments from the Porsuk River in Turkey. Environ Toxicol and Pharmacol 17, 111-116 (2004).
25. Hakura A, Shimada H, Nakajima M, Sui H, Kitamoto S, Suzuki S and Satoh T: Salmonella/human S9 mutagenicity test: a collaborative study with 58 compounds. Mutagenesis 20, 217-228 (2005).
26. Mortelmans K and Zeiger E: The Ames Salmonella/microsome mutagenicity assay. Mutat Res 455, 29-60 (2000).
27. Bernstein L, Kaldor J, McCann J and Pike MC: An empirical approach to the statistical analysis of mutagenesis dad from the Salmonella test. Mutat Res 97, 267-281 (1982).
28. Hansen AM, Wallin H, Binderuo ML, Dybdahl M, Autrup H, Loft S and Knudsen LE: Urinary 1-hydroxypyrene and mutagenicity in bus drivers and mail carriers exposed to urban air pollution in Denmark. Mutat Res 557, 7-17 (2004).
29. Simioli P, Lupi S, Gregório P, Siwinska E, Mielzynska D, Clonfero E and Pavanello S: Non-smoking coke oven workers show an occupational PAH exposure related increased in urinary mutagens. Mutat Res 562, 103-110 (2004).
30. Vermeulen R, Bos RP, Pertijs J and Kromhout H: Exposure related mutagens in urine of rubber workers associated with inhalable particulate and dermal exposure. Ocupp Environ Med 60, 97-103 (2003).
31. Hayes S: RK bacterial test for independently measuring chemical toxicity and mutagenicity: short-term forward selection assay. Mutat Res 130, 97-106 (1984).
32. Hellmer L and Bolcsfoldi G: An evaluation of the E. coli K-12 uvrB/recA DNA repair host mediated assay. Mutat Res 272, 145-160 (1992).
33. Zeiger E, Anderson B, Haworth S, Lawler T and Mortelmans K: Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals. Environ Mol Mutagen 19, 2-141 (1992).
34. Uuksulainen SO, Heikkilä PR, Olkinuora PS and Kiilunen M: Self-reported occupational health-hazards and measured exposures to airborne impurities and noise in shoe repair work. Int J Occup Environ Health 8, 320-327 (2002).
35. MacGregor D: The genetic toxicology of toluene. Mutat Res 317, 213-228 (1994).
36. Barry JP and Jenkinson P: Is ethanol genotoxic? A review of the published data. Mutagenesis 16, 91-101 (2001).
37. Cerná M, Pastorková A, Myers RS, Rössner P and Binková B: The use of a urine mutagenicity assay in the monitoring of environmental exposure togenotoxins. Mutat Res 391, 99-101 (1997).
38. Smith CJ, Bombick DW, Ryan BA, Morgan WT and Doolittle DJ: Urinary mutagenicity in nonsmokers follwing exposure to fresh diluted sidestream cigarette smoke. Mutat Res 470, 53-70 (2000).
39. Gabbani G, Pavanello S, Nardini B, Tognato O, Bordin A, Fornasa CV, Bezze G and Clonfero E: Influence of metabolic genotype GSTM1 on levels of urinary mutagens in patients treated topically with coal tar. Mutat Res 440, 27-33 (1999).
40. Heuser VD, Andrade VM, Silva J and Erdtman B: Comparison of genetic damage in brazilian footwear workers exposed to solvent-based or water-based adhesive. Mutat Res 583, 85-94 (2005).
41. Choi BCK, Connolly JG and Zhou RH: Application of urinary mutagen testing to detect workplace hazardous exposure and bladder cancer. Mutat Res 341, 207-216 (1995).
42. Bird MG, Greim H, Snyder R and Rice JM: International symposium: recent advances in benzene toxicity. Chem Biol Interact 153-154, 1-5 (2005).
43. Khan HA: Benzene's toxicity: a consolidated short review of human and animal studies. Hum Exp Toxicol 26, 677-685 (2007).