Magnitude of bacteraemia is a predictor of mortality during 1 year of follow-up

Epidemiology and Infection

Volumn 137, Issue 1, 2009, Pages 94-101

  Gradel, K O ^a   Sogaard M ^a   Dethlefsen, C ^a   Nielsen, H ^a   Schonheyder H C ^a  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE; AGED; ARTICLE; BACTEREMIA; BLOOD CULTURE; COMORBIDITY; CONTROLLED STUDY; DEATH; FEMALE; FOLLOW UP; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE SEPSIS; GRAM POSITIVE BACTERIUM; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; PREDICTION; RESPIRATORY TRACT INFECTION; SURGICAL PATIENT; URINARY TRACT INFECTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTEREMIA; BLOOD; COLONY COUNT, MICROBIAL; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; PROGNOSIS; RISK FACTORS;

EID: 57649123248     PISSN: 09502688     EISSN: 14694409     Source Type: Journal    
DOI: 10.1017/S0950268808000575     Document Type: Article

References (35)

1. Young LS. Sepsis syndrome. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases, 5th edn. Philadelphia: Churchill Livingstone, 2000, pp. 806-819.
2. Weinstein MP, et al. The clinical significance of positive blood cultures: A comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. II. Clinical observations, with special reference to factors influencing prognosis. Reviews of Infectious Diseases 1983; 5: 54-70.
3. Tilghman RC, Finland M. Clinical significance of bacteria in pneumococcic pneumonia. Archives of Internal Medicine 1937; 59 602-619.
4. Landsman JB. Bacteriaemia and prognosis in lobar pneumonia: The results of quantitative blood culture in pneumococcus pneumonia. Glasgow Medical Journal 1952; 33: 33-45.
5. Hall WH, Gold D. Shock associated with bacteremia; review of thirty-five cases. Archives of Internal Medicine 1955; 96: 403-412.
6. Weil MH, Spink WW. The shock syndrolpe associated with bacteremia due to gram-negative bacilli. Archives of Internal Medicine 1958; 101: 184-193.
7. DuPont HL, Spink WW. Infections due to gram-negative organisms: An analysis of 860 patients with bacteremia at the University of Minnesota Medical Center, 1958-1966. Medicine (Baltimore) 1969; 48: 07-332.
8. Kluge RM, DuPont HL. Factors affecting mortality of patients with bacteremia. Surgery, Gynecology & Obstetrics 1973; 137: 267-269.
9. Kreger BE, et al. Gram-negative bacteremia. III. Reassessment of etiology, epidemiology and ecology in 612 patients. American Journal of Medicine 1980; 68: 332-343.
10. Whimbey E, et al. Clinical significance of colony counts in immunocompromised patients with Staphylococcus aureus bacteremia. Journal of Infectious Diseases 1987; 155: 1328-1330.
11. Schonheyder HC, et al. Mortality rate and magnitude of Staphylococcus aureus bacteremia as assessed by a semiquantitative blood culture system. Scandinavian Journal of Infectious Diseases 1995; 27: 19-21.
12. Danmarks Statistik. Population statistics, Denmark (http://www.statistikbanken.dk). Accessed 1 September 2007.
13. Pedersen CB, et al. The Danish Civil Registration System. A cohort of eight million persons. Danish Medical Bulletin 2006; 53: 441-449.
14. Schønheyder HC, Højbjerg T. The impact of the first notification of positive blood cultures on antibiotic therapy. A one-year survey. Acta Pathologica, Microbiologica et Immunologica Scandinavica 1995; 103: 37-44.
15. Weinstein MP, et al. The clinical significance of positive blood cultures: A comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. I. Laboratory and epidemiologic observations. Reviews of Infectious Diseases 1983; 5: 35-53.
16. Weinstein MP, et al. Controlled evaluation of BacT/Alert standard aerobic and FAN aerobic blood culture bottles for detection of bacteremia and fungemia. Journal of Clinical Microbiology 1995; 33: 978-981.
17. Søgaard M, Nørgaard M, Schønheyder HC. First notification of positive blood cultures: High accuracy of the Gram stain report. Journal of Clinical Microbiology 2007; 45: 1113-1117.
18. Garner JS, et al. CDC definitions for nosocomial infections, 1988. American Journal of Infection Control 1988; 16: 128-140.
19. Friedman ND, et al. Health care-associated bloodstream infections in adults: A reason to change the accepted definition of community-acquired infections. Annals of Internal Medicine 2002; 137: 791-797.
20. Pedersen G, Schønheyder HC. Patients with bacteremia dying before notification of positive blood cultures: A 3-year clinical study. Scandinavian Journal of Infectious Diseases 1997; 29: 169-173.
21. Andersen TF, et al. The Danish National Hospital Register. A valuable source of data for modern health sciences. Danish Medical Bulletin 1999; 46: 263-268.
22. Charlson ME, et al. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. Journal of Chronic Diseases 1987; 40: 373-383.
23. Washington JA, Ilstrup DM. Blood cultures: Issues and controversies. Reviews of Infectious Diseases 1986; 8: 792-802.
24. Yagupsky P, Nolte FS. Quantitative aspects of septicemia. Clinical Microbiology Reviews 1990; 3: 269-279.
25. Khatib R, et al. Time to positivity in Staphylococcus aureus bacteremia: Possible correlation with the source and outcome of infection. Clinical Infectious Diseases 2005; 41: 594-598.
26. Marra AR, et al. Time to blood culture positivity as a predictor of clinical outcome of Staphylococcus aureus bloodstream infection. Journal of Clinical Microbiology 2006; 44: 1342-1346.
27. Peralta G, et al. Time to positivity in blood cultures of adults with Streptococcus pneumoniae bacteremia. BMC Infectious Diseases 2006; 6: 79.
28. Martinez JA, et al. Relationship of phylogenetic background, biofilm production, and time to detection of growth in blood culture vials with clinical variables and prognosis associated with Escherichia coli bacteremia. Journal of Clinical Microbiology 2006; 44: 1468-1474.
29. Peralta G, et al. Time-to-positivity in patients with Escherichia coli bacteraemia. Clinical Microbiology and Infection 2007; 13: 1077-1082.
30. Leibovici L, et al. Excess mortality in women with hospital-acquired bloodstream infection. American Journal of Medicine 2001; 111: 120-125.
31. Leibovici L, et al. Long-term survival following bacteremia or fungemia. Journal of the American Medical Association 1995; 274: 807-812.
32. Rangel-Frausto MS, et al. The dynamics of disease progression in sepsis: Markov modeling describing the natural history and the likely impact of effective antisepsis agents. Clinical Infectious Diseases 1998; 27: 185-190.
33. Rothman KJ. Epidemiology: An Introduction. Oxford, UK: Oxford University Press, 2002.
34. Li J, Plorde JJ, Carlson LG. Effects of volume and periodicity on blood cultures. Journal of Clinical Microbiology 1994; 32: 2829-2831.
35. Arendrup M, Jensen IP, Justesen T. Diagnosing bacteremia at a Danish hospital using one early large blood volume for culture. Scandinavian Journal of Infectious Diseases 1996; 28: 609-614.