The effects of the inhibitor of nuclear factor on lipopolysaccharide-induced cytokine expression in cultured human corneal fibroblasts

Chinese Journal of Ophthalmology

Volumn 44, Issue 1, 2008, Pages 61-66

  Chen, Guo Ling ^a   Wu, Xin Yi ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Corneal stroma; Cytokines; NF kappa B; Pyrrolidines; Thiocarbamates

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; THIOCARBAMIC ACID DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL CULTURE; CORNEA STROMA; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; SECRETION;

CELLS, CULTURED; CORNEAL STROMA; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; NF-KAPPA B; PYRROLIDINES; RNA, MESSENGER; THIOCARBAMATES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 57649121820     PISSN: 04124081     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Chen K, Long YM, Wang H, et al. Activation of nuclear factor-kappa B and effects of pyrrolidine dithiocarbamate on TNBS-induced rat colitis. World J Gastroenterol, 2005,14:1508-1514.
2. Kumagai N, Fukuda K, Fujitsu Y, et al. Role of structural cells of the cornea and conjunctiva in the pathogenesis of vernal keratoconjunctivitis. Prog Retin Eye Res, 2006,25:165-187.
3. Kumagai N, Fukuda K, Fujitsu Y, et al. Lipopolysaccharide-induced expression of intercellular adhesion molecule-1 and chemokines in cultured human corneal fibroblasts. Invest Ophthalmol Vis Sci, 2005,46:114-120.
4. Lu Y, Fukuda K, Nakamura Y, et al. Inhibitory effect of triptolide on chemokine expression induced by proinflammatory cytokines in human corneal fibroblasts. Invest Ophthalmol Vis Sci, 2005,46:2346-2352.
5. Chinese source.
6. Fukuda K, Kumagai N, Yamamoto K, et al. Potentiation of lipopolysaccharide- induced chemokine and adhesion molecule expression in corneal fibroblasts by soluble CD14 or LPS-binding protein. Invest Ophthalmol Vis Sci, 2005,46:3095-3101.
7. Linda Ch, Ming-Shium H, Hsin-Chiu H, et al. Stimulation of inducible nitric oxide synthase by monosodium urate crystals in macrophages and expression of iNOS in gouty arthritis. Nitric Oxide, 2004,11:228-236.
8. Chen K, Long YM, Wang H, et al. Activation of nuclear factor-kappa B and effects of pyrrolidine dithiocarbamate on TNBS-induced rat colitis. World J Gastroenterol, 2005,14:1508-1514.
9. Sun ZW, Andersson R. NF-κB activation and inhibition: a review. Shork, 2002,18:99-106.
10. Wilson SJ, Leone BA, Anderson D, et al. Immunohistochemical analysis of the activation of NF-kappaB and expression of associated cytokines and adhesion molecules in human models of allergic inflammation. J Pathol, 1999,189:265-272.
11. Matsumoto K, Ikema K, Tanihara H. Role of cytokines and chemokines in pseudomonal keratitis. Cornea,2005,24:S43-S49.
12. Hazlett LD, Rudner XL, McClellan SA, et al. Role of IL-12 and IFN-γ in Pseudomonas aeruginosa corneal infection. Invest Ophthalmol Vis Sci, 2002,43:419-424.
13. Kumagai N, Fukuda K, Fujitsu Y, et al. Lipopolysaccharide-induced expression of intercellular adhesion molecule-1 and chemokines in cultured human corneal fibroblasts. Invest Ophthalmol Vis Sci, 2005,46:114-120.
14. Maertzdorf J, Osterhaus AD, Veijans GM. IL-17 expression in human herpetic stromal keratitis: modulatory effects on chemokine production by corneal fibroblasts. J Immunol, 2002, 169: 5897-5903.
15. Zhang J, Wu XY, Yu FS. Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection. Curr Eye Res, 2005,30:527-534.
16. Fukuda K, Kumagai N, Yamamoto K, et al. Potentiation of lipopolysaccharide-induced chemokine and adhesion molecule expression in corneal fibroblasts by soluble CD14 or LPS-binding protein. Invest Ophthalmol Vis Sci, 2005,46:3095-3101.
17. Chinese source.
18. El Eter E, Hagar HH, Al-Tuwaijiri A, et al. Nuclear factor-kappaB inhibition by pyrrolidine dithiocarbamate attenuates gastric ischemia- reperfusion injury in rats. Can J Physiol Pharmacol, 2005,83:483-492.
19. Parodi FE, Mao D, Ennis TL. Suppression of experimental abdominal aortic aneurysms in mice by treatment with pyrrolidine dithiocarbamate, an antioxidant inhibitor of nuclear factor-kappaB. J Vasc Surg, 2005,41:479-489.